Search results for "74"
showing 10 items of 820 documents
rara & rarissima
2018
Down-regulation of the MHC class I antigen-processing machinery after oncogenic transformation of murine fibroblasts
1998
Malignant transformation is often associated with genetic alterations providing tumor cells with mechanisms for escape from immune surveillance. Human and murine tumors of various origin as well as in vitro models of viral and oncogenic transformation express reduced levels of major histocompatibility complex (MHC) class I antigens resulting in decreased sensitivity to MHC class I-restricted cytotoxic T lymphocyte (CTL)-mediated lysis. We here investigate whether the suppressed MHC class I surface expression of ras-transformed fibroblasts is due to dysregulation of the genes of the antigen-processing machinery, the peptide transporters TAP-1 and TAP-2 and the proteasome subunits LMP-2 and L…
Major Histocompatibility Complex Modulation and Loss
2002
L’allattamento tra cura e cultura: dall’Africa all’ipertrofia tecnologica
2017
L’allattamento è una pratica finora poco studiata dall’antropologia culturale e medica, atto che si colloca tra la natura e la cultura, tra la sfera privata e quella sociale della donna e che, come la nascita e la gravidanza. Esso esprime in dinamiche biopolitiche che denotano l’organizzazione della società stessa, le gerarchie nei ruoli e i rapporti di genere. In quanto pratica culturale, l’allattamento si differenzia in base all’appartenenza sociale ed etnica della madre e del neonato, portando con sé delle differenze rituali come nella legge della “parentela di latte” nelle società musulmane o nei tabu apotropaici dell’Africa subsahariana. Il saggio propone alcune riflessioni su quanto t…
La tecnología Blockchain en la construcción de espacios económicos de impacto social positivo
2021
espanolEste trabajo realiza un estudio del universo de la tecnologia blockchain y su aplicacion en el mundo del siglo XXI a traves del analisis de diferentes espacios virtuales construidos con ella. El objetivo ultimo de este analisis es valorar y comprender las posibilidades que esta tecnologia aporta en la construccion de procesos con un alto impacto social y/o ambiental. A tal efecto, se lleva a cabo una investigacion exploratoria a traves del estudio de casos significativos o pioneros desde una perspectiva socio-tecnologica. Los resultados concluyen que, si bien en sus origenes la tecnologia blockchain se estructuro con una marcada perspectiva financiera, el transcurso del tiempo ha dem…
Multi-Destination Trips and Tourism Statistics: Empirical Evidences in Sicily
2012
Abstract The knowledge of the actual magnitude and main features of tourism flows in a given destination is an essential prerequisite for the evaluation of tourism impacts and externalities. Indeed, many pleasure trips are often characterized by the visit to more than a single destination. Although the topic is well-documented in literature, the empirical results are limited to a few pioneering studies. The lack may be attributable to the failure of tourism organizations to collect data on multi-destination trip behaviour. This can be seen, for example, in the system of European statistics on tourism (according to the Council Directive 95/57 EC), where information on the average number of v…
The effects of fiscal policies on the economic growth in Romania
2017
This paper intends to examine the results of fiscal policy implementation in Romania, their impact on economic growth and how fiscal policies have influenced the growth of budgetary deficits. Our objective is to highlight and explore efficient fiscal consolidation strategies that can ensure a stable economic growth through sustainable public finances. The methodology consists in analysing the information provided by national and international financial institutions, comparing it to past, proposed and assumed values, and examining the efforts and results. The conclusion we reached was that, in order to restore the sustainability of public finances, the need arises for considerable fiscal con…
La eclosión de la prensa satírica en España (1868-1874)
2018
espanolEl nacimiento y consolidacion de la prensa satirica en el periodo revolucionario de 1868-1874, constituye el tema central de este trabajo. Convertidos en instrumento de propaganda por los liberales desde 1808, los periodicos satiricos pronto demostraron su capacidad de influencia sobre un pueblo que, si no podia leer, al menos podia escuchar recitados sus textos o ver sus dibujos comicos. A traves de estos periodicos se desarrollo una intensa y eficaz via de politizacion que culmina en la situacion revolucionaria de 1868-1874 con la proliferacion de cabeceras y la emergencia de sendas culturas politicas: una revolucionaria democratica, otra contrarrevolucionaria carlista. EnglishThe …
La distribución de cerámica y materiales de construcción en España
2007
La caracterización de las empresas de un sector es esencial para com- prender la situación de la distribución comercial y analizar su evolución. En el presente trabajo abordamos el estudio de los distribuidores de material cerámico y de construcción en España a partir de fuentes de información primaria y secundaria. La lectura conjunta de los resultados obtenidos a par- tir de ambas fuentes de datos permite realizar una primera aproximación a la situación de un sector que ha experimentado un extraordinario crecimiento en los últimos años. Characterization of firms in a sector is essential to understand the situation of commercial distribution and monitor developments. In this paper we study…
Money for the Issuer: Liability or Equity?
2021
Abstract This study analyzes the nature of money through the lens of the international principles of accounting and lays the foundations of what it calls the accounting view of money (AVM). Using international accounting principles, the AVM argues that the fiat monies issued by the state (typically, cash, banknotes, and central bank money) are not debt and that in fractional reserve regimes, only a share of commercial bank money can be regarded as debt. The AVM argues, instead, that state monies and the nondebt share of commercial bank money are net wealth of their holders and net worth (equity) of their issuers and determines how the seigniorage associated with money issuance should be acc…