Search results for "7t"
showing 10 items of 95 documents
Huygens: lost – regained – revised. De literair-historische receptie van Constantijn Huygens in de eerste helft van de 19e eeuw
2018
Huygens: lost ‒ regained ‒ revised. De literair-historische receptievan Constantijn Huygens in de eerste helftvan de 19e eeuwFrom the beginning of professional Dutch Studies M. Siegenbeek’s inauguration as professor eloquentiae hollandicae extraordinarius, 1797 the 17th century Dutch writers P.C. Hooft and Joost van den Vondel are present in Dutch literary studies and literary historiography. The position of ConstantijnHuygens, whom the contemporary literary scholars also include in the Grote Vijf Great Five of the 17th-century Dutch literature besides Vondel, Hooft, Cats and Bredero, was gradually changing during the 19th century. This article postulates that the reception of Huygens in …
The face of conflict: Significant sharp force trauma to the mid-facial skeleton in an individual of probable 16th–17th century date excavated from By…
2016
A variety of injuries have always been associated with violence, consequences of which people had to deal with. In this paper we present a complex of craniofacial and dental injuries resulted from sharp force trauma. The basis of our study was historical skeletal material excavated from archeological site in Byczyna (11th–17th century), Poland. An individual whose skeleton was exhumed from the grave No. 610 exhibited healed, oblique trauma of the left maxilla, damage to the crowns of right central and lateral incisors and concomitant luxation of the right maxillary central incisor. We describe the mechanism of this trauma and complications that resulted from damage to the masticatory appara…
Parental effects on offspring longevity--evidence from 17th to 19th century reproductive histories.
2004
Family studies provide support for a modest genetic influence on offspring life span, although the magnitude of these correlations is small.The study aimed to clarify the relative contributions of parental age at birth and overall parental longevity on offspring lifespan, and to identify the biological and cultural mechanisms.Information was derived from two village genealogies (1650-1927) encompassing 9979 births (5315 males, 4664 females). Data selection was guided by the inclusion of information about parental age at birth and lifespan, offspring lifespan and cohort-specific life expectancy.Parental age at reproduction displayed a negative association with offspring survivability, which …
Yersinia pestis DNA from Skeletal Remains from the 6th Century AD Reveals Insights into Justinianic Plague
2013
Yersinia pestis, the etiologic agent of the disease plague, has been implicated in three historical pandemics. These include the third pandemic of the 19th and 20th centuries, during which plague was spread around the world, and the second pandemic of the 14th–17th centuries, which included the infamous epidemic known as the Black Death. Previous studies have confirmed that Y. pestis caused these two more recent pandemics. However, a highly spirited debate still continues as to whether Y. pestis caused the so-called Justinianic Plague of the 6th–8th centuries AD. By analyzing ancient DNA in two independent ancient DNA laboratories, we confirmed unambiguously the presence of Y. pestis DNA in…
A historical case of beaten-copper cranium
2007
The authors present the oldest historical case of a so-called beaten-copper cranium. The typical pattern was identified on a skull from a child, probably a boy, who died at approximately 6 years of age and was buried in a provisional cemetery used during the siege of Hanau, Germany, in 1635 and 1636. Morphological and radiological analyses of the severe digitate impressions ubiquitous on the child's endocranium support the diagnosis of chronically elevated intracranial pressure due to hydrocephalus.
Molecular evidence of HLA-B27 in a historical case of ankylosing spondylitis
2005
MTHFR C677T allelic variant is not associated to plasma and cerebrospinal fluid homocysteine in amyotrophic lateral sclerosis
2014
Amiotrophic lateral sclerosis (ALS) is a neurological disorder with a multifactorial etiopathogenesis including excitotoxicity, intracellular calcium increase and mitochondrial damage together with oxidative stress and apoptosis. Overall, the relationship between homocysteine (Hcy), motoneuron death and ALS appears to be complex and still under investigation. It has been already shown that Hcy is elevated in plasma and cerebrospinal fluid (CSF) of ALS patients, although mechanisms of hyperhomocysteinemia have not been elucidated yet. MTHFR C677T variant is the most common genetic determinant of increased homocysteinemia, but no studies regarding the effect of this polymorphism in ALS patien…
Investigation of mass graves in the Churchyard of St. Gertrude’s, Riga, Latvia
2011
The methylenetetrahydrofolate reductase C677T polymorphism and the risk of congenital heart diseases: a literature review
2014
Congenital Heart Diseases (CHDs) are the most commonand serious developmental anomaly and the leading non-infectious cause of mortality in the first year of life. Despite the advances in diagnosis and treatment, understanding of the developmental causes and aetiologies of CHDs has been limited. The hyperhomocysteinemia is one of the proved risk factors related to the occurrence of CHDs. The connection between cardiac defects, folate and hyperhomocysteinemia could be explained by a mutation in the methylenetetrahydrofolate reductase (MTHFR) gene. Indeed, the C677T MTHFR mutation produces a thermolabile variant of MTHFR with reduced enzymatic action resulting in higher plasma levels of homocy…
Plaques-boucles byzantines et apparentées de la période VIe-VIIe siècle trouvées en France
2014
The paper provides an inventory of buckle plates thought to be Byzantine found in France : the Sucidava type and its offshoots, those with an openwork cross or in the form of a cross, the family of buckle plates in the shapes of lyres or tongues, and a few individual pieces. Relatively numerous, these sartorial accessories enjoyed a popularity that has ensured their recognition locally even today.