Search results for "81"
showing 10 items of 2468 documents
Hierarchical imaging and computational analysis of three-dimensional vascular network architecture in the entire postnatal and adult mouse brain
2021
The formation of new blood vessels and the establishment of vascular networks are crucial during brain development, in the adult healthy brain, as well as in various diseases of the central nervous system. Here, we describe a step-by-step protocol for our recently developed method that enables hierarchical imaging and computational analysis of vascular networks in postnatal and adult mouse brains. The different stages of the procedure include resin-based vascular corrosion casting, scanning electron microscopy, synchrotron radiation and desktop microcomputed tomography imaging, and computational network analysis. Combining these methods enables detailed visualization and quantification of t…
Paenibacillus larvae Chitin-Degrading Protein PlCBP49 Is a Key Virulence Factor in American Foulbrood of Honey Bees
2014
Paenibacillus larvae, the etiological agent of the globally occurring epizootic American Foulbrood (AFB) of honey bees, causes intestinal infections in honey bee larvae which develop into systemic infections inevitably leading to larval death. Massive brood mortality might eventually lead to collapse of the entire colony. Molecular mechanisms of host-microbe interactions in this system and of differences in virulence between P. larvae genotypes are poorly understood. Recently, it was demonstrated that the degradation of the peritrophic matrix lining the midgut epithelium is a key step in pathogenesis of P. larvae infections. Here, we present the isolation and identification of PlCBP49, a mo…
Cinquanta anys de Cuadernos de Geografía
2014
Gozos de S. Vicente de Paul para las Hijas de la Caridad
Il·lustració del sant situada entre el goig Text del goig a tres col. separades per dobles filets i, també, a línia tirada
Zvaigžņotā Debess: 2014/15, Ziema (226)
2014
Contents: “ZVAIGŽŅOTĀ DEBESS” FORTY YEARS AGO: J.Stradiņš. Vestige of Otto Schmidt in Latvia (abridged) ; Leonora Roze. All-Union Conference in Latvian State University (abridged) ; DEVELOPMENTS in SCIENCE: K.Schwartz. Gravitational Waves and Cosmic Inflation ; DISCOVERIES: A.Alksnis. Light Echoes from Supernova 2014J in Galaxy M82 ; A.Alksnis. Discovery of the Benešov Meteorites 20 Years after the Bolide Event ; I.Pundure. Giant Filament on the Sun Watched by NASA's SDO ; I.Pundure. MAVEN’s Mars Exploration Mission Started ; SPACE RESEARCH and EXPLORATION: R.Misa. Plasma Engines and Ad Astra Rocket Company ; LATVIAN SCIENTISTS: J.Freimanis. Reviewing My 60 Years of Life (concluded) ; KĀRLI…
The results of the vine varieties reconversion measures in the North-Eastern Romania / Résultats de la mesure de reconversion des cépages dans le Nor…
2016
The vine varieties reconversion measure is one of the many benefits that the Romania's integration to the European Union brings to the wine sector. This study aims to analyze the results of this measure during 2007–2015 in the Romania's North-East Region. From the Vineyard Plantation Register, the plots noble vine parcels of each department were divided into two groups: those who existed in the field in before and those converted during the period. The surface of each group was classified first, based on the color of the grapes and secondarily, based on the pair international varieties – non international varieties. The conversion affected 3 of 6 departments. In Iasi, where the proportion o…
Las imágenes de los perpetradores, los artefactos de los perpetradores: el archivo nómade de Tuol Sleng (S-21)
2016
Este ensayo analiza la producción y circulación de las fotografías de las fichas de dete-nidos tomadas por la maquinaria del Jemer Rojo en el centro de tortura S-21 (Phnom Penh). Al momento de tomar las fotografías, estas jugaron un rol esencial en el proceso de identificación, represión y asesinato de quienes eran considerados enemigos del régimen de la Kampuchea Democrática (1975-1979). No obstante, tras la caída de los Jemeres Rojos, estas fotografías fueron utilizadas para denunciar a quienes las habían tomado, como si las imágenes no conservaran rastros de su función original y fueran reversibles. Por esto las trasladaron desde los museos y galerías de arte a los escena-rios, de los li…
PML nuclear body-residing proteins sequentially associate with HPV genome after infectious nuclear delivery.
2019
Subnuclear promyelocytic leukemia (PML) nuclear bodies (NBs) are targeted by many DNA viruses after nuclear delivery. PML protein is essential for formation of PML NBs. Sp100 and Small Ubiquitin-Like Modifier (SUMO) are also permanently residing within PML NBs. Often, large DNA viruses disassemble and reorganize PML NBs to counteract their intrinsic antiviral activity and support establishment of infection. However, human papillomavirus (HPV) requires PML protein to retain incoming viral DNA in the nucleus for subsequent efficient transcription. In contrast, Sp100 was identified as a restriction factor for HPV. These findings suggested that PML NBs are important regulators of early stages o…
Disertacion en defensa del episodio de Virgilio sobre los amores de Eneas y de Dido / dicha en Italiano por el abate don Juan Andres ... ; y traducid…
1788
Sig.: A14, []1 Vinyeta a port. Notes a peu de p. - Reclams
Disertacion en defensa del episodio de Virgilio sobre los amores de Eneas y de Dido
Sig.: A14, []1 Vinyeta a port Notes a peu de p. - Reclams