Search results for "9(55)"
showing 10 items of 87 documents
Scientometrics analysis of research activity and collaboration patterns in Chagas cardiomyopathy.
2018
Background Chagas cardiomyopathy is a serious and common complication of Chagas disease. Methods Through bibliometric and Social Network Analysis, we examined patterns of research on Chagas cardiomyopathy, identifying the main countries, authors, research clusters, and topics addressed; and measuring the contribution of different countries. Results We found 1932 documents on Chagas cardiomyopathy in the MEDLINE database. The most common document type was ‘journal article’, accounting for 79.6% of the total (n = 1538), followed by ‘review’ (n = 217, 11.2%). The number of published records increased from 156 in 1980–1984 to 311 in 2010–2014. Only 2.5% were clinical trials. Brazil and the USA …
Chagas Disease Vector Control in a Hyperendemic Setting: The First 11 Years of Intervention in Cochabamba, Bolivia
2014
Background Chagas disease has historically been hyperendemic in the Bolivian Department of Cochabamba. In the early 2000s, an extensive vector control program was implemented; 1.34 million dwelling inspections were conducted to ascertain infestation (2000–2001/2003–2011), with blanket insecticide spraying in 2003–2005 and subsequent survey-spraying cycles targeting residual infestation foci. Here, we assess the effects of this program on dwelling infestation rates (DIRs). Methodology/Principal Findings Program records were used to calculate annual, municipality-level aggregate DIRs (39 municipalities); very high values in 2000–2001 (median: 0.77–0.69) dropped to ∼0.03 from 2004 on. A linear…
Comparison of two PCR methods for detection of Leptospira interrogans in formalin-fixed and paraffin-embedded tissues
2012
In this study we compared two polymerase chain reaction (PCR) methods using either 16S ribosomal RNA (rRNA) or 23S rRNA gene primers for the detection of different Leptospira interrogans serovars. The performance of these two methods was assessed using DNA extracted from bovine tissues previously inoculated with several bacterial suspensions. PCR was performed on the same tissues before and after the formalin-fixed, paraffin-embedding procedure (FFPE tissues). The 23S rDNA PCR detected all fresh and FFPE positive tissues while the 16S rDNA-based protocol detected primarily the positive fresh tissues. Both methods are specific for pathogenic L. interrogans. The 23S-based PCR method successfu…
Quelle politique pour la culture ? Florilège des débats 1955-2014
2014
International audience
Redes de colaboración y autorías científicas sobre la enfermedad de Chagas: análisis de las publicaciones indexadas en PubMed (1940-2009)
2012
Chagas disease is a chronic, tropical, parasitic disease, endemic throughout Latin America. The large-scale migration of populations has increased the geographic distribution of the disease and cases have been observed in many other countries around the world. To strengthen the critical mass of knowledge generated in different countries, it is essential to promote cooperative and translational research initiatives. We analyzed authorship of scientific documents on Chagas disease indexed in the Medline database from 1940 to 2009. Bibliometrics was used to analyze the evolution of collaboration patterns. A Social Network Analysis was carried out to identify the main research groups in the are…
La hospitalización domiciliaria: antecedentes, situación actual y perspectivas
2001
Objetivo. Determinar las distintas variantes que ha tenido el concepto de la hospitalización domiciliaria a lo largo del tiempo, para así contribuir al debate sobre las circunstancias que inciden en la gestión sanitaria frente a futuros retos. Métodos. Se revisa la literatura sobre la atención domiciliaria como modalidad asistencial de salud mediante una exploración de las publicaciones indizadas en MEDLINE, LILACS y el Índice Médico Español durante el período de 1995-2000. Resultados. La hospitalización domiciliaria ha tenido un desarrollo desigual a lo largo del tiempo en diferentes países y son varios los modelos de este tipo de atención, cada uno con sus respectivas ventajas y desventaj…
Vācu civilās pārvaldes ekonomiskā politika okupētajā Latvijā 1941.-1944.
2014
Promocijas darbā „Vācu civilās pārvaldes ekonomiskā politika okupētajā Latvijā 1941 – 1944” tiek pētīta vācu ekonomiskā politika Latvijas ģenerālapgabalā, vācu civilās okupācijas pārvaldes pastāvēšanas laikam nosakot pētījuma hronoloģisko ietvaru. Darba galvenā uzmanība tiek pievērsta okupācijas varas saimnieciskai koncepcijai un tās izpausmēm ekonomikā, tostarp lauksaimniecības politikā, ilgstošajā reprivatizācijas jautājumā, rūpniecībā. Skatīta tiek arī Latvijas Zemes pašpārvaldes loma ekonomiskajos procesos, Latvijas iedzīvotāju iesaistīšana sabiedriskajos darbos, gūstekņu nodarbināšana un to kopējā nozīme ekonomikā, kā arī Latvijas iedzīvotāju attieksme pret okupācijas varu saimniecisko…
On the Age of Leprosy
2014
Leprosy is a chronic infection of the skin and nerves caused by Mycobacterium leprae and the newly discovered Mycobacterium lepromatosis. Human leprosy has been documented for millennia in ancient cultures. Recent genomic studies of worldwide M. leprae strains have further traced it along global human dispersals during the past ∼ 100,000 years. Because leprosy bacilli are strictly intracellular, we wonder how long humans have been affected by this disease-causing parasite. Based on recently published data on M. leprae genomes, M. lepromatosis discovery, leprosy bacilli evolution, and human evolution, it is most likely that the leprosy bacilli started parasitic evolution in humans or early h…
Phylogeography and genetic variation of Triatoma dimidiata, the main Chagas disease vector in Central America, and its position within the genus Tria…
2008
Background Among Chagas disease triatomine vectors, the largest genus, Triatoma, includes species of high public health interest. Triatoma dimidiata, the main vector throughout Central America and up to Ecuador, presents extensive phenotypic, genotypic, and behavioral diversity in sylvatic, peridomestic and domestic habitats, and non-domiciliated populations acting as reinfestation sources. DNA sequence analyses, phylogenetic reconstruction methods, and genetic variation approaches are combined to investigate the haplotype profiling, genetic polymorphism, phylogeography, and evolutionary trends of T. dimidiata and its closest relatives within Triatoma. This is the largest interpopulational …
Efficacy of an insecticide paint against malaria vectors and nuisance in West Africa--part 2: field evaluation.
2010
Abstract Background Widespread resistance of the main malaria vector Anopheles gambiae to pyrethroids reported in many African countries and operational drawbacks to current IRS methods suggest the convenience of exploring new products and approaches for vector control. Insecticide paint Inesfly 5A IGR™, containing two organophosphates (OPs), chlorpyrifos and diazinon, and one insect growth regulator (IGR), pyriproxyfen, was tested in Benin, West Africa, for 12 months. Methods Field trials were conducted in six experimental huts that were randomly allocated to one or two layers of insecticide at 1 Kg/6 m2 or control. Evaluations included: (i) early mosquito collection, (ii) mosquito release…