Search results for "A2"
showing 10 items of 1101 documents
Collaborative Mobile Clouds: An Energy Efficient Paradigm for Content Sharing
2018
On the way toward enabling efficient content distribution, reducing energy consumption and prolonging battery life of mobile equipment, an emerging paradigm, i.e., mobile cloud, which is based on content distribution, was proposed. As a mobile platform that is oriented toward content distribution, mobile cloud is also foreseen as an energy-efficient solution for future wireless networks. The benefits of using CMC for content distribution or distributed computing from social networking perspectives have been studied earlier. In this article, we first present the concepts of CMC and then discuss the energy-efficiency benefits from the system-level point-of-view as well as open challenges in d…
L’ampliamento come occasione di recupero della memoria e dell’identità
2012
We present the enlargement plan of an isolated cemetery in a small town of the west Sicily as it exemplifies some way to carry out the design for an “addition”. The enlargement faces a still readable and characteristic nineteenth-century building. Even introducing unavoidable innovative characteristics, the architecture we designed tries to resolve the difficult relationship between the new portion and the old cemetery, bell shaped, in steep slope above the town. The recovery of this place for collective memory, once realized as a closed enclosure, is realized by the mediation of a space which seeks to maintain, recover and reinforce the identity of places altered in the last years by uncon…
Reconfigurable DNA Origami Nanocapsule for pH-Controlled Encapsulation and Display of Cargo
2019
DNA nanotechnology provides a toolbox for creating custom and precise nanostructures with nanometer-level accuracy. These nano-objects are often static by nature and serve as versatile templates for assembling various molecular components in a user-defined way. In addition to the static structures, the intrinsic programmability of DNA nanostructures allows the design of dynamic devices that can perform predefined tasks when triggered with external stimuli, such as drug delivery vehicles whose cargo display or release can be triggered with a specified physical or chemical cue in the biological environment. Here, we present a DNA origami nanocapsule that can be loaded with cargo and reversibl…
Substrate Selectivity of Coumarin Derivatives by Human CYP1 Enzymes: In Vitro Enzyme Kinetics and In Silico Modeling
2021
Of the three enzymes in the human cytochrome P450 family 1, CYP1A2 is an important enzyme mediating metabolism of xenobiotics including drugs in the liver, while CYP1A1 and CYP1B1 are expressed in extrahepatic tissues. Currently used CYP substrates, such as 7-ethoxycoumarin and 7-ethoxyresorufin, are oxidized by all individual CYP1 forms. The main aim of this study was to find profluorescent coumarin substrates that are more selective for the individual CYP1 forms. Eleven 3-phenylcoumarin derivatives were synthetized, their enzyme kinetic parameters were determined, and their interactions in the active sites of CYP1 enzymes were analyzed by docking and molecular dynamic simulations. All cou…
Microwave-Assisted Esterification of Tall Oil Fatty Acids with Methanol Using Lignin-Based Solid Catalyst
2016
During alkaline pulping significant amounts of lignin, carbohydrates (mostly hemicelluloses), and extractives (tall oil soap and turpentine) are removed from wood feedstock. In this study, the catalytic esterification of fatty acids in tall oil with methanol to produce fatty acid methyl esters under microwave irradiation was performed at 100 °C for 10–60 min. A novel heterogeneous acid catalyst tested for this purpose was synthesized from the hardwood alkali lignin that was precipitated by acidification from the black liquor from soda-AQ pulping. The comparative reaction data were obtained by using other solid catalysts, Amberlyst 15, and p-toluenesulfonic acid. The results showed the highe…
Oxidovanadium(v) complexes with l-proline-based amino acid phenolates
2019
Abstract l -proline was used to prepare chiral, tridentate amino acid phenol proligands H2L1–4. These proligands react with vanadium precursors VO(acac)2, VOSO4∙5H2O and VO(OPr)3 in methanol to form the corresponding oxidoalkoxidovanadium( v ) complexes 1–4. The complexes crystallize from methanol, and are octahedrally coordinated with a general formula [VO(L1–4)(OMe)(MeOH)]. In solution, however, they adopt several different conformations or isomeric structures depending on the solvent.
Integrin-mediated Cell Adhesion to Type I Collagen Fibrils
2004
In the integrin family, the collagen receptors form a structurally and functionally distinct subgroup. Two members of this subgroup, α1β1 and α2β1 integrins, are known to bind to monomeric form of type I collagen. However, in tissues type I collagen monomers are organized into large fibrils immediately after they are released from cells. Here, we studied collagen fibril recognition by integrins. By an immunoelectron microscopy method we showed that integrin α2I domain is able to bind to classical D-banded type I collagen fibrils. However, according to the solid phase binding assay, the collagen fibril formation appeared to reduce integrin α1I and α2I domain avidity to collagen and to lower …
Finite element approximation for a div-rot system with mixed boundary conditions in non-smooth plane domains
1984
The authors examine a finite element method for the numerical approximation of the solution to a div-rot system with mixed boundary conditions in bounded plane domains with piecewise smooth boundary. The solvability of the system both in an infinite and finite dimensional formulation is proved. Piecewise linear element fields with pointwise boundary conditions are used and their approximation properties are studied. Numerical examples indicating the accuracy of the method are given. peerReviewed
Fixed point results for α-implicit contractions with application to integral equations
2016
Recently, Aydi et al. [On fixed point results for α-implicit contractions in quasi-metric spaces and consequences, Nonlinear Anal. Model. Control, 21(1):40–56, 2016] proved some fixed point results involving α-implicit contractive conditions in quasi-b-metric spaces. In this paper we extend and improve these results and derive some new fixed point theorems for implicit contractions in ordered quasi-b-metric spaces. Moreover, some examples and an application to integral equations are given here to illustrate the usability of the obtained results.
Physical properties of aerosol particles measured from a bubbling fluidized bed boiler
2015
Abstract Increased use of biomass and waste fuels, and the consequent corrosion problem have led to an increased need to study and monitor the combustion processes. This study presents an extensive physical characterization of aerosol particles measured from a bubbling fluidized bed boiler with different fuel mixtures and optional ferric sulfate feeding. The fuel mixtures included bark, sludge, peat and solid recovered fuel. Previously, the characterization of the particles analyzed from a fluidized bed reactor has mainly focused on chemical off-line analysis of collected impactor samples, large coarse mode particles or laboratory-scale reactors. In this study, the focus is in the particle …