Search results for "A2"

Fruits and vegetables protect against the genotoxicity of heterocyclic aromatic amines activated by human xenobiotic-metabolizing enzymes expressed i…

2010

Heterocyclic aromatic amines (HAAs) can be formed during the cooking of meat and fish at elevated temperatures and are associated with an increased risk for cancer. On the other hand, epidemiological findings suggest that foods rich in fruits and vegetables can protect against cancer. In the present study three teas, two wines, and the juices of 15 fruits and 11 vegetables were investigated for their protective effect against the genotoxic effects of 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP). To closely mimic the enzymatic activation of these HAAs in humans, genetically engineered V79 Chinese hamster fibroblasts were employed tha…

Pellets based on polyuronates: Relationship between gelation and release properties

2017

International audience; Three polyuronates: amidated low methoxyl pectin (ALMP), low methoxyl pectin (LMP) and polygalacturonic acid (PGA) were used to encapsulate rutin in pellets, and they were characterized by different techniques (macroscopic properties, Calcium and rutin release). The ability of the three polyuronates to bind calcium ions and the viscoelastic properties of gels were performed to relate the properties of the pellets to the gel structures. The pellets size, the water content, the water uptake, the release of calcium and rutin varied depending on the polyuronate used. The pellets size of ALMP were smaller than LMP and PGA with a lower water content, but this matrix was mo…

Application of Potassium Ion Impregnated Titanium Dioxide as Nanocatalyst for Transesterification of Linseed Oil

2018

The current work comprises the investigation of biodiesel production from linseed oil using TiO2 and a potassium L-tartrate monobasic (C4H5KO6)-modified TiO2 nanocatalyst. Different amounts of C4H5KO6 were considered for TiO2 modification. The nanocatalyst TiO2–0.5C4H5KO6 (1:0.5 molar ratio) showed the best conversion rate for biodiesel production. The nanocatalyst was characterized by FTIR, XRD, TEM, BET, and XPS, and the Hammett indicator–benzenecarboxylic acid titration method was used for basicity measurement. The biodiesel was characterized by GC-MS and 1H and 13C NMR. Furthermore, the optimum reaction parameters for transesterification reaction were analyzed, and the yield was determi…

Fractional Maximal Functions in Metric Measure Spaces

2013

Abstract We study the mapping properties of fractional maximal operators in Sobolev and Campanato spaces in metric measure spaces. We show that, under certain restrictions on the underlying metric measure space, fractional maximal operators improve the Sobolev regularity of functions and map functions in Campanato spaces to Hölder continuous functions. We also give an example of a space where fractional maximal function of a Lipschitz function fails to be continuous.

Tailoring the excitation of fundamental flexural guide waves in coated bone by phase-delayed array: Two-dimensional simulations

2015

The fundamental flexural guided wave (FFGW) enables ultrasonic assessment of cortical bone thickness. In vivo, it is challenging to detect this mode, as its power ratio with respect to disturbing ultrasound is reduced by soft tissue covering the bone. A phase-delayed ultrasound source is proposed to tailor the FFGW excitation in order to improve its power ratio. This situation is analyzed by 2D finite-element simulations. The soft tissue coating (7-mm thick) was simulated as a fluid covering an elastic plate (bone, 2–6 mm thick). A six-element array of emitters on top of the coating was excited by 50-kHz tone bursts so that each emitter was appropriately delayed from the previous one. Respo…

Service Provisioning and User Association for Heterogeneous Wireless Railway Networks

2017

In addition to comforting passengers' journey, the modern railway system is responsible to support a variety of on-board Internet services to meet the passenger's demands on seamless service provisioning. In order to provide wireless access to the train, one idea attracting increasing attention is to deploy a series of track-side access points (TAPs) with high-speed data rates along the rail lines dedicated to the broadband mobile service provisioning on board. Due to the heavy data traffic flushing into the base stations (BSs) of the cellular networks, TAPs act as a complement to the BSs in data delivery. In this paper, we focus on the TAP association problem for service provisioning in a …

Service Provisioning with Multiple Service Providers in 5G Ultra-dense Small Cell Networks

2015

In this work, a game theoretical approach for addressing the virtual network service providers (NSPs), small cell provider (SCP) and user interaction in heterogenous small cell networks is presented. In particular, we consider the users can select the services of different NSPs based on their prices. The NSPs have no dedicated hardware and need to rent from the SCP in term of radio resources, e.g., small cell base stations (SBSs) in order to provide satisfied services to the users. Due to the fact that the selfish parties involved aim at maximizing their own profits, a hierarchical dynamic game framework is presented to address interactive decision problem. In the lower-level, a Stackelberg…

Review Article: Recommended reading list of early publications on atomic layer deposition - Outcome of the "virtual Project on the History of ALD"

2017

A novel splice acceptor site mutation in the ATP2A2 gene in a family with Darier disease

2016

This study identifies a novel spice site mutation in the ATP2A gene in a family with the Darier disease

The closure of Pak1-dependent macropinosomes requires the phosphorylation of CtBP1/BARS

2007

Membrane fission is an essential process in membrane trafficking and other cellular functions. While many fissioning and trafficking steps are mediated by the large GTPase dynamin, some fission events are dynamin independent and involve C-terminal-binding protein-1/brefeldinA-ADP ribosylated substrate (CtBP1/BARS). To gain an insight into the molecular mechanisms of CtBP1/BARS in fission, we have studied the role of this protein in macropinocytosis, a dynamin-independent endocytic pathway that can be synchronously activated by growth factors. Here, we show that upon activation of the epidermal growth factor receptor, CtBP1/BARS is (a) translocated to the macropinocytic cup and its surroundi…