Search results for "ABC"
showing 10 items of 170 documents
Antithrombotic therapy in acute coronary syndromes
2000
Current therapy of acute coronary syndromes (i.e., unstable angina and non-Q-wave myocardial infarction, Q-wave myocardial infarction) consists of thrombolytic, anti-platelet, and anti-coagulant therapy. In most cases of acute coronary syndromes, the pathogenesis is a mural thrombus formation on a ruptured or eroded atherosclerotic plaque. Both platelets and thrombin play an essential role in the pathophysiology of acute coronary syndromes. Aspirin and heparin are essential treatments for patients with acute coronary syndromes. Novel thrombin and platelet inhibitors have been developed and demonstrated useful effects for improving both acute and long-term clinical outcomes in acute coronary…
Adherence to the mediterranean diet modulates the association between the abca1 gene, plasma lipids and diabetes in a high-risk population
2014
Neonatal Respiratory Insufficiency Caused by an (Homozygous) ABCA3-Stop Mutation: a Systematic Evaluation of Therapeutic Options
2014
Background Autosomal recessive ABCA3 (ATP-binding cassette protein A3) gene mutations have been associated with neonatal respiratory distress and pediatric interstitial lung disease. The clinical course of the disease depends on the underlying mutations. Therefore, knowledge of course, symptoms and treatment of the disease is important. Patient and methods A term newborn suffered from progressive respiratory insufficiency, which led to death at the age of 4.8 months. The girl developed interstitial lung disease. Infections as well as structural and functional disorders of the lung were systematically excluded. A homozygous c.4681C > T (Arg 1561 Stop) mutation of the ABCA3 gene was identifie…
Alakouluikäisten lasten yksilöllisten taustatekijöiden yhteydet motorisiin perustaitoihin
2016
Tutkimuksen tarkoituksena oli tutkia, miten alakouluikäiset selviytyivät motorisia perustaitoja mittaavista testeistä. Lisäksi tarkasteltiin yksilön rakenteellis-ten taustatekijöiden (pituus, paino, painoindeksi, sukupuoli) yhteyksiä motorisiin perustaitoihin sekä sitä, millaisia eroja on motorisesti kömpelöiden (kehityksellisen koordinaatiohäiriön riskiryhmään kuuluvien) ja taitavien välillä. Aineistonkeräys suoritettiin Keski-Suomen ja Pirkanmaan alueilla sijaitsevissa kuudessa koulussa vuoden 2013 keväällä. Oppilaiden motorisia perus-taitoja mitattiin M-ABC-2 testipatteristolla. Oppilaat jaettiin iän mukaan kahteen ryhmään, 7—10 sekä 11—13 vuotiaisiin. Muuttujia analysoitiin riippumattom…
Comptabilité à base d'activités (ABC) et activités informatiques : une contribution à l'amélioration des processus informatiques d'une banque
2010
The aim of the paper is to describe the Activity-based Costing and Management methods applied in France. For that purpose, we use a literature review and a case study. In a first time, we analyse the origins of the methods and their diffusion. Then we present the French situation. Finally, we propose a case study that takes place in a French bank. Our paper shows that the ABC and ABM methods are as developed in France as in the Anglo-Saxon countries and that the methods are strategically oriented.
IMPACT OF NON-ALCOHOLIC FATTY LIVER DISEASE ON CARDIOVASCULAR RISK IN A GENERAL POPULATION
2019
Background: Background:Nonalcoholic fatty liver (NAFL) is a major cause of liver disease worldwide leading also to a higher risk of cardiovascular events. We aimed to evaluate the impact of fatty liver and fibrosis on cardiovascular risk factors in a general population. Methods: 604 subjects included in the community-based ABCD (Alimentazione, Benessere Cardiovascolare e Diabete) study were recruited. Steatosis (CAP >288 dB/m) and fibrosis (> 8.7 KPa by M and > 7.2 KPa by XL probe) were assessed with FibroScan Cardiovascular risk was evaluated by the Atherosclerotic Cardiovascular Disease (ASCVD) risk estimator and de ned low if <5%, borderline if 5%-7 4%, intermediate if 7-9% a…
Induction of neuronal plasticity during adulthood. Role of cortical interneurons and plasticity-related molecules.
2019
La complejidad del sistema nervioso de los vertebrados representa un reto a la hora de conocer su funcionamiento. Hace ya más de cien años que se postuló la neurona como unidad básica de procesamiento, generación y transmisión de la información a través de este sistema, y, con el paso de los años, ha evolucionado el conocimiento sobre esta unidad funcional. La idea clásica del sistema nervioso central (SNC) adulto es la de un tejido asombrosamente interconectado y complejo, pero prácticamente inmutable y muy poco adaptable a los cambios. No obstante, esta visión se ha ido desplazando, formándose una nueva idea del SNC adulto que, aunque de manera más limitada que durante el desarrollo, tamb…
Designing P-Chirogenic 1,2-Diphosphinobenzenes at Both P-Centers Using P(III)-Phosphinites
2016
International audience; A new enantiodivergent synthesis of P-chirogenic 1,2-diphosphinobenzenes (DP*B) bearing the chirality on one or both phosphorus centers is reported using aryne chemistry. The principle is based on successive reactions of 1,2-dibromobenzene with sec-phosphide boranes, then DABCO to remove the borane, and finally with chlorophosphines or P(III)-chirogenic phosphinites. The efficiency of this synthesis was demonstrated by the stereoselective preparation of (S,S)-1,2-bis(o-anisylphenylphosphino)benzene. A comparison of DIPAMP and homochiral DP*B ligands in asymmetric Rh- or Pd-catalyzed reactions was reported.
Studying the Cognitive Map of the US States: Ideology and Prosperity Stereotypes Predict Interstate Prejudice
2018
What are the spontaneous stereotypes that U.S. citizens hold about the U.S. states? We complemented insights from theory-driven approaches to this question with insights from a novel data-driven approach. Based on pile sorting and spatial arrangement similarity ratings for the states, we computed two cognitive maps of the states. Based on ratings for the states on ∼20 candidate dimensions, we interpreted the dimensions that spanned the two maps (Studies 1 and 2). Consistent with the agency/socioeconomic success, conservative-progressive beliefs, and communion (ABC) model of spontaneous stereotypes, these dimensions that participants spontaneously used to rate the states’ similarity included…
ABC saimes gēnu ekspresija un vēža cilmes šūnu fenotipiskās izpausmes pret doksorubicīnu rezistentā MDA-MB-231 apakšpopulācijā
2018
Rezistence pret citotoksiskiem ķīmijterapijas savienojumiem ir nozīmīga problēma vēža ārstēšanā, kam raksturīga audzēja atjaunošanās un slimības progresēšana. Rezistenci pret ķīmijterapijas savienojumiem var veidot dažādi šūnu mehānismi, no kuriem visplašāk aprakstīta ATF saistošās kasetes (ABC) transportproteīnu pārekspresija. Rezistenci visbiežāk veicina pret ķīmijterapijas savienojumiem rezistentu apakšpopulāciju selekcija. Vēža cilmes šūnām (VCŠ) piemīt spēja izvairīties no ķīmijterapijas ietekmes un atjaunot audzēja šūnu populāciju. Darba mērķis bija noteikt ABC saimes gēnu ekspresiju un raksturot VCŠ raksturīgās pazīmes pret doksorubicīnu rezistentā trīskārši negatīva krūts vēža šūnu …