Search results for "ABO"

Theoretical basis for the use of non-invasive thermal measurements to assess the brain injury in newborns undergoing therapeutic hypothermia.

2020

AbstractThe aim of this paper is to propose a new non-invasive methodology to estimate thermogenesis in newborns with perinatal asphyxia (PA) undergoing therapeutic hypothermia (TH). Metabolic heat production (with respect to either a neonate’s body mass or its body surface) is calculated from the newborn’s heat balance, estimating all remaining terms of this heat balance utilising results of only non-invasive thermal measurements. The measurement devices work with standard equipment used for therapeutic hypothermia and are equipped with the Global System for Mobile Communications (GSM), which allows one to record and monitor the course of the therapy remotely (using an internet browser) wi…

The metabolic syndrome in hypertension: European society of hypertension position statement.

2008

The metabolic syndrome considerably increases the risk of cardiovascular and renal events in hypertension. It has been associated with a wide range of classical and new cardiovascular risk factors as well as with early signs of subclinical cardiovascular and renal damage. Obesity and insulin resistance, beside a constellation of independent factors, which include molecules of hepatic, vascular, and immunologic origin with proinflammatory properties, have been implicated in the pathogenesis. The close relationships among the different components of the syndrome and their associated disturbances make it difficult to understand what the underlying causes and consequences are. At each of these …

Role of adipokines in obesity-associated hypertension

2010

It has been well documented that obesity is a major risk factor for the development of the hypertensive state. The correlation between body mass index and blood pressure level is well established. Nevertheless, the exact mechanisms which contribute to obesity-related hypertension remain poorly understood. In the last years, we have realized that the white adipose tissue is not just an inert organ for nutrient storage and isolation but rather depending on the body mass index the biggest endocrinological organ. Thus, the possible contribution of adipokines to the blood pressure elevation becomes an attractive hypothesis to explain the hypertensive state that often occurs in obesity. In this r…

P330Modifications of short-term heart rate varibility and intrinsic pacemaker variability in an experimental model of metabolic syndrome

2018

P674Metabolic deregulation in myocardial infarction is mediated by PGC-1 alpha pathway

2014

Purpose: In the context of myocardial infarction (MI) the availability of metabolites is clearly restricted, therefore a fuel metabolic shifts takes place. Previous studies have indicated that peroxisome proliferator activated receptor co-activator alpha (PGC-1α) pathway is a crucial regulator of cardiac metabolism in response to cardiac stress. Here we address the role of PGC-1α in regulating metabolic changes of MI. Methods: We studied a group of 12 common swine in which anterior MI was induced by means of angioplasty balloon inflation. A series of 6 swine were sacrificed at 48h post-infarction (acute infarction group) and another series of 6 swine were sacrificed at 3 weeks (chronic infa…

Concurrent strength and sprint training increases resting metabolic rate in masters road cyclists

2020

High-intensity concurrent sprint and strength training has been shown to provide a strong physiological training stimulus in young adult endurance athletes. However, the effect in veteran endurance athletes remains unknown. This study examined if replacing a portion of endurance training with concurrent sprint and strength training influenced resting metabolic rate (RMR) and lean mass (LM) in veteran endurance cyclists. Eighteen well-trained male veteran road cyclists (55.2 ± 8.4 years; 7.9 ± 1.1 training hrs/wk; 323 ± 53 Wpeak) were allocated to a concurrent strength and sprint training group (CT, n = 9) or control group (CON, n = 9). The CT group completed a 12-weeks of sprint and strengt…

A systematic review of physical fitness, physiological demands and biomechanical performance in equestrian athletes

2012

This article presents a systematic review of the literature investigating physical fitness, physiological demands and biomechanical performance in equestrian athletes. Three databases (SportsDiscus, CAB abstracts and PubMed) were searched to identify the literature. The main search term of ‘horse-riding’ was combined with eleven specific keywords (‘fitness’, ‘physiology’, ‘biomechanics’, ‘equestrian’, ‘athlete’, ‘co-ordination’, ‘heart rate’, ‘oxygen consumption’ ‘kinematic’ ‘EMG’ and ‘skill’). Exclusion criteria were: conference proceedings, abstracts, theses, and non-peer reviewed articles. Subsequently, 15 peer-reviewed papers were identified and included within this review. The main re…

Self-reported reasons for on-duty sleepiness among commercial airline pilots

2021

Experimental and epidemiological research has shown that human sleepiness is determined especially by the circadian and homeostatic processes. The present field study examined which work-related factors airline pilots perceive as causing on-duty sleepiness during short-haul and long-haul flights. In addition, the association between the perceived reasons for sleepiness and actual sleepiness levels was examined, as well as the association between reporting inadequate sleep causing sleepiness and actual sleep-wake history. The study sample consisted of 29 long-haul (LH) pilots, 28 short-haul (SH) pilots, and 29 mixed fleet pilots (flying both SH and LH flights), each of whom participated in a…

Early, but not late onset estrogen replacement therapy prevents oxidative stress and metabolic alterations caused by ovariectomy.

2014

Aims: The usefulness of estrogen replacement therapy (ERT) in preventing oxidative stress associated with menopause is controversial. We aimed to study if there is a critical time window for effective treatment of the effects of ovariectomy with estrogens at the molecular, metabolic, and cellular level. Results: Our main finding is that early, but not late onset of ERT prevents an ovariectomy-associated increase in mitochondrial hydrogen peroxide levels, oxidative damage to lipids and proteins, and a decrease in glutathione peroxidase and catalase activity in rats. This may be due to a change in the estrogen receptor (ER) expression profile: ovariectomy increases the ER α/β ratio and immedi…

Muscle Free Fatty-Acid Uptake Associates to Mechanical Efficiency During Exercise in Humans

2018

Intrinsic factors related to muscle metabolism may explain the differences in mechanical efficiency (ME) during exercise. Therefore, this study aimed to investigate the relationship between muscle metabolism and ME. Totally 17 healthy recreationally active male participants were recruited and divided into efficient (EF; n = 8) and inefficient (IE; n = 9) groups, which were matched for age (mean ± SD 24 ± 2 vs. 23 ± 2 years), BMI (23 ± 1 vs. 23 ± 2 kg m−2), physical activity levels (3.4 ± 1.0 vs. 4.1 ± 1.0 sessions/week), and V˙O2peak (53 ± 3 vs. 52 ± 3 mL kg−1 min−1), respectively, but differed for ME at 45% of V˙O2peak intensity during submaximal bicycle ergometer test (EF 20.5 ± 3.5 vs. I…