Search results for "ABO"

showing 10 items of 13628 documents

Endocrine and pro-inflammatory activity of visceral (VAT) and subcutaneous (SAT) adipose tissue in morbidly obese patients with and without metabolic…

2011

metabolic syndrome VAT SATSettore MED/13 - Endocrinologia
researchProduct

Relationships between metabolic syndrome and steady and pulsatile components of clinic and 24-h blood pressure

2006

metabolic syndrome blood pressure
researchProduct

Relationship between metabolic syndrome and left ventricular structure and function in subjects with isolated clinic hypertension

2007

metabolic syndrome left ventricular structure and function isolated clinic hypertension
researchProduct

Reduce cardiovascular risk through close follow up of the metabolic syndrome during menopause in women: a possible goal

2009

After a treatment period a significant reduction of BMI. HDL-cholesterol, tryglicerides, diastolic blood pressure and fasting blood glucose, in menopausal women with metabolic syndrome, were performed, as well as a significant reduction of score of relative cardiovascular risk

metabolic syndrome menopauseSettore MED/13 - Endocrinologia
researchProduct

Influence of metabolic syndrome on clinic and 24-h pulse pressure in essential hypertension.

2007

metabolic syndrome pulse pressure hypertension
researchProduct

Huippu-urheilun ja pitkäaikaisen liikuntaharrastuksen yhteys metabolisen syndrooman ja sen komponenttien hypertension ja dyslipidemian prevalenssiin

2010

metabolinen syndroomadyslipidemiahypertensioentinen huippu-urheilijametabolinen oireyhtymäfyysinen aktiivisuusurheilijat
researchProduct

Maksimaalisen aerobisen hapenottokykytestin metaboliset vasteet vesijuoksussa verrattuna juoksumatolla juoksuun

2017

Johdanto. Vesijuoksua voidaan pitää korvaavana sekä vammoja ennaltaehkäisevänä harjoitusmuotona. Vesijuoksuharjoittelu mahdollistaa aerobisen suorituskyvyn ylläpitämisen sekä kehittämisen ilman, että alaraajat kuormittuvat yhtä suuresti kuin maalla juoksussa. Harjoittelussa tulisi kuitenkin ottaa huomioon lajinomaisuuden säilyttäminen ja se vaatii veden vaikutuksen ymmärtämistä vesijuoksussa saavutettuihin metabolisiin vasteisiin. Tämän tutkimuksen tarkoituksen oli vertailla maksimaalisen aerobisen vesi- ja juoksumattotestin metabolisia vasteita toisiinsa ja selvittää aiheuttavatko testit saman suuruista alaraajojen väsymystä. Menetelmät. Tutkimukseen osallistui 21 (8 naista, 13 miestä), 20…

metaboliset vasteetkestävyysjuoksuvesijuoksuaerobinen suorituskyky
researchProduct

Translation of HTT mRNA with expanded CAG repeats is regulated by the MID1-PP2A protein complex.

2012

Expansion of CAG repeats is a common feature of various neurodegenerative disorders, including Huntington's disease. Here we show that expanded CAG repeats bind to a translation regulatory protein complex containing MID1, protein phosphatase 2A and 40S ribosomal S6 kinase. Binding of the MID1-protein phosphatase 2A protein complex increases with CAG repeat size and stimulates translation of the CAG repeat expansion containing messenger RNA in a MID1-, protein phosphatase 2A- and mammalian target of rapamycin-dependent manner. Our data indicate that pathological CAG repeat expansions upregulate protein translation leading to an overproduction of aberrant protein and suggest that the MID1-com…

metabolism [Microtubule Proteins]General Physics and AstronomyHTT protein humanRibosomal s6 kinaseMice0302 clinical medicinemetabolism [Transcription Factors]Protein Phosphatase 2Luciferasesgenetics [Nerve Tissue Proteins]genetics [Protein Biosynthesis]0303 health sciencesHuntingtin ProteinMultidisciplinarybiologyTOR Serine-Threonine KinasesNuclear ProteinsTranslation (biology)3. Good healthmetabolism [Luciferases]Microtubule Proteinsddc:500metabolism [Nuclear Proteins]genetics [Trinucleotide Repeat Expansion]Protein Bindingcongenital hereditary and neonatal diseases and abnormalitiesMTOR protein humanUbiquitin-Protein LigasesBlotting WesternNerve Tissue Proteinsmetabolism [TOR Serine-Threonine Kinases]metabolism [RNA Messenger]General Biochemistry Genetics and Molecular Biology03 medical and health sciencesgenetics [RNA Messenger]mental disordersHuntingtin ProteinAnimalsHumansEukaryotic Small Ribosomal SubunitRNA MessengerNucleotide Motifs030304 developmental biologyMessenger RNAmetabolism [Nerve Tissue Proteins]RNAmetabolism [Protein Phosphatase 2]General ChemistryProtein phosphatase 2Molecular biologynervous system diseasesProtein Biosynthesisbiology.proteinTrinucleotide repeat expansionTrinucleotide Repeat Expansion030217 neurology & neurosurgeryMid1 protein humanHeLa CellsTranscription FactorsNature communications
researchProduct

The E3 Ubiquitin Ligase MID1 Catalyzes Ubiquitination and Cleavage of Fu

2014

Sonic Hedgehog (SHH)-GLI signalling plays an important role during embryogenesis and in tumorigenesis. The survival and growth of several types of cancer depend on autonomously activated SHH-GLI signalling. A protein complex containing the ubiquitin-ligase MID1 and protein phosphatase 2A (PP2A) regulates the nuclear localization and transcriptional activity of GLI3, a transcriptional effector molecule of SHH, in cancer cell lines with autonomously activated SHH signalling. However, the exact molecular mechanisms that mediate the interaction between MID1 and GLI3 remained unknown. Here, we show that MID1 catalyses the ubiquitination and proteasomal cleavage of the GLI3-regulator Fu. Our data…

metabolism [Microtubule Proteins]Ubiquitin-conjugating enzymeBiochemistrymetabolism [Protein Serine-Threonine Kinases]Ubiquitinmetabolism [Transcription Factors]Nuclear proteinSonic hedgehogbiologymetabolism [Protein-Serine-Threonine Kinases]Nuclear Proteinsrespiratory systemProtein-Serine-Threonine KinasesUbiquitin ligaseGene Expression Regulation NeoplasticGLI3 protein humanBiochemistryddc:540embryonic structuresMicrotubule Proteinsmetabolism [Hedgehog Proteins]Function and Dysfunction of the Nervous Systemmetabolism [Nuclear Proteins]Signal Transductionmetabolism [Kruppel-Like Transcription Factors]Proteasome Endopeptidase Complexanimal structuresSTK36 protein humanUbiquitin-Protein LigasesKruppel-Like Transcription FactorsNerve Tissue ProteinsProtein Serine-Threonine Kinaseschemistry [Ubiquitin-Protein Ligases]CatalysisZinc Finger Protein Gli3Cell Line TumorGLI3HumansHedgehog Proteinsmetabolism [Proteasome Endopeptidase Complex]metabolism [Cell Nucleus]Molecular Biologychemistry [Lysine]DNA PrimersCell Nucleusmetabolism [Nerve Tissue Proteins]UbiquitinLysineUbiquitinationCell BiologyProtein phosphatase 2chemistry [Ubiquitin]Proteasomebiology.proteinSHH protein humanhuman activitiesMid1 protein humanHeLa CellsTranscription FactorsJournal of Biological Chemistry
researchProduct

Analytical model for the long- distance tracer-transport in plants

2011

International audience; Recent investigations of long-distance transport in plants using non-invasive tracer techniques such as C radiolabeling monitored by positron emission tomography (PET) combined with magnetic resonance imaging (MRI) revealed the need of dedicated methods to allow a quantitative data analysis and comparison of such experiments. A mechanistic compartmental tracer transport model is presented, defined by a linear system of partial differential equations (PDEs). This model simplifies the complexity of axial transport and lateral exchanges in the transport pathways of plants (e.g. the phloem) by simulating transport and reversible exchange within three compartments using j…

metabolism [Plant Structures]Transport pathwaysPlant RootsNuclear magnetic resonanceCarbon RadioisotopesPositron emissiontomography(PET)11CPartial differential equationFourier AnalysisApplied MathematicsLinear systemfood and beveragesGeneral MedicinePlantsphysiology [Biological Transport]Magnetic Resonance Imagingmetabolism [Plants]Jddc:580Modeling and SimulationPositron emission tomography (PET)Beta vulgarisGeneral Agricultural and Biological SciencesBiological systemmetabolism [Zea mays]AlgorithmsSimulationStatistics and ProbabilityMaterials scienceC-11metabolism [Phloem]Data analysisPhloemZea maysModels BiologicalGeneral Biochemistry Genetics and Molecular Biologymetabolism [Plant Roots]RaphanusXylemTRACERddc:570metabolism [Carbon Radioisotopes]Computer SimulationSensitivity (control systems)Radioactive TracersGeneral Immunology and Microbiologymetabolism [Xylem]Biological Transportmetabolism [Raphanus]metabolism [Beta vulgaris]Positron-Emission TomographyConstant (mathematics)Plant Structures
researchProduct