Search results for "ADAM"
showing 10 items of 372 documents
Intercettazioni no limits: il captatore informatico “per istradamento”
2021
L’utilizzo del captatore informatico a mezzo della tecnica dell’istradamento si presta a distorsioni e abusi. Ci si trova di fronte a uno strumento itinerante del quale è impossibile prevedere gli spostamenti, sommato a una tecnica captativa elusiva dei confini giurisdizionali. Dopo una breve ricostruzione degli interventi giurisprudenziali e legislativi che hanno consentito di disciplinare processualmente l’utilizzo del “virus-spia”, vengono messe in evidenza le aporie attualmente esistenti e si individuano i pretesti usati dalla prassi per una sempre più ampia fruibilità dei risultati delle intercettazioni con captatore. Con particolare riguardo alle primissime applicazioni giurisprudenzi…
Velando armas
2002
La nuova Intesa con la Regione Ecclesiastica Sicilia sui beni culturali ecclesiastici alla luce del sistema concordatario italiano: l’atipicità diven…
2012
The main topic analysed in the essay is the outline of civil ecclesiastical law about the Agreement (Intesa), signed in 2010 by the Regione Siciliana and the Regione Ecclesiastica Sicilia, aimed at the protection, preservation and development of the ecclesiastical cultural heritage. By moving from the specialty of the Sicilian model in regulating and administrating such heritage, and by analyzing its effects on the specific system that regulates the same ecclesiastical component, the primary goal is to focus on the atypical elements carried onto the Agreement, which appear to be connected to the practice of such special prerogatives by the Regional Government; and paying particular attentio…
"Penso a Turandot non finita!". Riflessioni sul capolavoro incompiuto di Giacomo Puccini
2019
Il saggio ricostruisce gli ultimi mesi della vita di Giacomo Puccini, con particolare riferimento alla composizione del terzo atto di "Turandot", agli abbozzi lasciati dall'autore al momento della morte (Bruxelles 1924) e ai successivi interventi compositivi e di orchestrazione realizzati da Franco Alfano.
Gozos al apostol Santiago, Patron de España.
El full orlat Grav. xil. enmarcat del sant, flanquejat per gerros amb flors Text del goig a dues col. separades per banda
2018
Oncogenic human papillomaviruses (HPV) are small DNA viruses that infect keratinocytes. After HPV binding to cell surface receptors, a cascade of molecular interactions mediates the infectious cellular internalization of virus particles. Aside from the virus itself, important molecular players involved in virus entry include the tetraspanin CD151 and the epidermal growth factor receptor (EGFR). To date, it is unknown how these components are coordinated in space and time. Here, we studied plasma membrane dynamics of CD151 and EGFR and the HPV16 capsid during the early phase of infection. We find that the proteinase ADAM17 activates the extracellular signal-regulated kinases (ERK1/2) pathway…
Melittin Modulates Keratinocyte Function through P2 Receptor-dependent ADAM Activation
2012
Melittin, the major component of the bee venom, is an amphipathic, cationic peptide with a wide spectrum of biological properties that is being considered as an anti-inflammatory and anti-cancer agent. It modulates multiple cellular functions but the underlying mechanisms are not clearly understood. Here, we report that melittin activates disintegrin-like metalloproteases (ADAMs) and that downstream events likely contribute to the biological effects evoked by the peptide. Melittin stimulated the proteolysis of ADAM10 and ADAM17 substrates in human neutrophil granulocytes, endothelial cells and murine fibroblasts. In human HaCaT keratinocytes, melittin induced shedding of the adhesion molecu…
Unsaturated Fatty Acids Drive Disintegrin and Metalloproteinase (ADAM)-dependent Cell Adhesion, Proliferation, and Migration by Modulating Membrane F…
2011
The disintegrin-metalloproteinases ADAM10 and ADAM17 mediate the release of several cell signaling molecules and cell adhesion molecules such as vascular endothelial cadherin or L-selectin affecting endothelial permeability and leukocyte transmigration. Dysregulation of ADAM activity may contribute to the pathogenesis of vascular diseases, but the mechanisms underlying the control of ADAM functions are still incompletely understood. Atherosclerosis is characterized by lipid plaque formation and local accumulation of unsaturated free fatty acids (FFA). Here, we show that unsaturated FFA increase ADAM-mediated substrate cleavage. We demonstrate that these alterations are not due to genuine ch…
Adamantylcalixarenes with CMPO groups at the wide rim: synthesis and extraction of lanthanides and actinides
2007
Abstract Starting from p -adamantylcalix[4]- and [6]arenes functionalized with carboxylic acid or ester groups at the adamantane nuclei, carbamoylmethylphosphine oxide (CMPO)-containing ligands of a novel type were synthesized. They were studied as extractants for a series of f-block elements including radioactive 152 Eu(III), 241 Am(III), 233 U(VI), and 239 Pu(IV). Tetrameric ligand 4b in which CMPO residues are connected to adamantane nuclei through methylene groups gave the best extraction results for lanthanides and actinides. For all the ligands the extraction efficiency does not decrease at higher nitric acid concentration. Although the discrimination between trivalent actinides and l…
Latvijas Universitātes Teoloģijas fakultātes mācību spēku darbība Latvijas Evaņģēliski luteriskajā baznīcā no 1919. līdz 1940. gadam
2018
Maģistra darbs “Latvijas Universitātes Teoloģijas fakultātes darbība Latvijas Evaņģēliski luteriskajā baznīcā no 1919. līdz 1940. gadam” mērķis izpētīt Latvijas Universitātes Teoloģijas fakultātes mācību spēku darbību Latvijas Evaņģēliski Luterisko baznīcā, galvenokārt Teoloģijas fakultātes ietekmi uz Latvijas Evaņģēliski luteriskās baznīcas vadību. Darbā tiks apskatīta Latvijas valstu kristīgās konfesijas teoloģiskā izglītība iespējas un Latvijas valdības attieksmi pret teoloģisko izglītību. Sniegs vispārēju apskatu par Latvijas Evaņģēliski luteriskās baznīcas izveidi un struktūru, kā arī to viedokli par mācītāju izglītību. Tad detalizēti tiks apskatīta Latvijas Universitātes Teoloģijas fa…