Search results for "ADAM"
showing 10 items of 372 documents
P3‐335: Upstream of N‐ras (UNR) is involved in translational control of ADAM10 protein expression
2008
Background: The amyloid beta peptide (A ) is derived by proteolytic processing of the amyloid precursor protein (APP) by the beta-secretase BACE1 and gamma-secretase. In contrast to this amyloidogenic processing, APP is predominantly cleaved by the alpha-secretase within the A domain and this precludes the formation of A . We and other research groups could show that BACE1 protein expression is regulated by the 5’untranslated region (UTR) of the BACE1 mRNA, however little is known about the regulation of alpha-secretase. Similar to the 5’UTR of BACE1, the 5’UTR of ADAM10 consists of 444 nucleotides with a GC-content of 70% and two upstream open reading frames. We hypothesize that ADAM10, th…
Beiträge zur Geschichte des Musikunterrichts an den Gelehrtenschulen der östlichen Ostseeregion im 16. und 17. Jahrhundert
2005
De la cratopolítica a la cinicocracia
2004
Real-time hermeneutics : meaning-making in ludonarrative digital games
2015
Experiencia y verdad en la hermenéutica de Gadamer. Algunos problemas
2006
Gadamer vincula su concepción de la experiencia hermenéutica a una interpretación especulativa de la verdad que no se justifica simplemente por la exigencia de superar el enfoque metódico. Este ensayo responde al propósito de indagar hasta qué punto esta interpretación sólo supera la escisión fenomenológica entre conciencia y objeto en tanto que remite a un fundamento ontológico de su unidad, que pasa a ocupar la posición de sujeto. Nuestra hipótesis es que el concepto gadameriano de la verdad como una «infinitud de sentido» genera tensiones con su concepción de la experiencia hermenéutica, que permanecen irresueltas. También intentaremos mostrar que una de las consecuencias que se siguen d…
L’appropriation gadamérienne de l’esthétique ingardienne des œuvres d’art architecturales
2014
International audience
Le prolongement gadamérien de l’esthétique kantienne
2014
International audience
L'anonymat du donneur de gamètes face au droit d'accès aux archives
2016
International audience; En l’espèce, le Conseil d’État apprécie si le refus de communiquer des informations et documents concernant un donneur de gamètes porte atteinte au droit d’accès aux archives invoqué par la personne conçue grâce à ce don. Le juge considère que le refus, fondé sur le respect du principe d’anonymat, ne fait pas obstacle à son droit d’accès dans la mesure où le délai de communicabilité n’a pas expiré.
La reconduction de la parole à la praxis chez Gadamer et Wittgenstein
2011
The humour in science fiction litterature : identification ans specification of its contours, its attributes, its techniques and its variations
2014
This thesis is divided in two parts. The first part suggests a theory of humour, it starts studying that concept by explaining its enunciative, logical or syntactical structures in order to draw a clear vision of it, before offering a first attempt to define it. Then it establishes necessary distinctions between the various categories of the risible to refine the delineation of the contours of humour. Once the concept is marked out, the theory of humour suggests an original typology of humourous themes and a study of the three main variations of humour, before focusing on its purpose. The second part discusses, in the light of certain concepts developed in the first part, the question of hu…