Search results for "ADC"

P-selectin glycoprotein ligand-1 as a potential target for humoral immunotherapy of multiple myeloma.

2008

Monoclonal antibodies (mAbs), successfully adopted in the treatment of several haematological malignancies, have proved almost ineffective in multiple myeloma (MM), because of the lack of an appropriate antigen for targeting and killing MM cells. Here, we demonstrate that PSGL1, the major ligand of P-Selectin, a marker of plasmacytic differentiation expressed at high levels on normal and neoplastic plasma cells, may represent a novel target for mAb-mediated MM immunotherapy. The primary effectors of mAb-induced cell-death, complement-mediated lysis (CDC) and antibody-dependent cell-mediated cytotoxicity (ADCC), were investigated using U266B1 and LP1 cell-lines as models. Along with immunolo…

ADM : A Density And Priority Levels Aware Protocol For Broadcasting In Vehicular Ad-Hoc Networks

2014

The broadcasting communication mode is widely used in Vehicular Ad~hoc Networks (VANETs). It is used for sending emergency messages, road-traffic information or to help routing protocols to determine routes. This communication mode is known to be hard to achieve efficiently since it depends on the network density. Indeed, broadcasting methods may cause network congestion if they are not well designed. This paper introduces a novel Autonomic Dissemination Method (ADM) which delivers messages in accordance with given message classes and network density levels. The proposed approach is based on two steps: an offline optimization process and an online adaptation to the network characteristics. …

Audiovisual constructs of Paralympic Games : scalarity and camera angle

2014

This research will analyze the variables differentiating between the audiovisual television of the XIII edition of the Paralympic Games and the Games of the XXIX Olympiad, held in Beijing from the 7th of September to the 17th, 2008. This study will serve as a methodological basis for similar future research. By means of a qualitative and quantitative methodology, this study also focuses on determining if TV representations of Paralympic sportspersons favour their social integration or if, on the contrary, lead to higher stigmatization.

Ensemble Planning for Digital Audio Broadcasting

2003

Minimum node weight spanning trees searching algorithm for broadcast transmission in sensor networks

2017

A minimum node weight spanning tree in a weighted, directed graph is a tree whose node with maximum out-weight is minimal among all spanning trees. This type of trees are important because they appear in the solutions of the maximum lifetime broadcasting problem in wireless sensor networks. In a complete graph build of N nodes there are NN-2 spanning trees and to find such trees it is necessary to perform more than O(NN-2) operations. In this paper we propose an algorithm for searching the minimum node weight spanning trees in the graph. In the proposed algorithm, instead of calculating the symbolic determinant of the generalized Laplacian matrix, numerical operations on its exponents are p…

Design And Characterization Of Automated Color Sensor System

2017

Abstract The paper presents a color sensor system that can process light reflected from a surface and produce a digital output representing the color of the surface. The end-user interface circuit requires only a 3-bit pseudo flash analog-to-digital converter (ADC) in place of the conventional/typical design comprising ADC, digital signal processor and memory. For scalability and compactness, the ADC was designed such that only two comparators were required regardless of the number of color/wavelength to be identified. The complete system design has been implemented in hardware (bread board) and fully characterized. The ADC achieved less than 0.1 LSB for both INL and DNL. The experimental r…

Atomic resolution imaging of beryl: an investigation of the nano-channel occupation

2016

(C) 2016 The Authors. Journal of Microscopy published by JohnWiley & Sons, Ltd on behalf of the Royal Microscopical Society. This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

Media for the minorities: Russian language media in Estonia 1990–2012

2013

This article aims to explore the ways in which Estonian public broadcasting tackles one specific media service sphere; how television programmes for language minorities are created in a small country, how economics and European Union media policy have influenced this processes. The article highlights major tensions, namely between Estonian and Russian media outlets, Estonian and Russian speakers within Estonia and the EU and Estonia concerning the role of public service broadcasting (PSB). For research McQuail’s (2010) theoretical framework of media institutions’ influencers – politics, technology and economics – is used. For analyses media regulatory acts and audience surveys are accomplis…

SmartARP: merging IP and MAC addressing for low-cost gigabit Ethernet networks

1999

Abstract Address Resolution Protocol (ARP) is one of the key TCP/IP stack protocols, used on LANs to map 32 bit IP addresses into 48 bit hardware addresses. Regular ARP uses MAC layer broadcasts to perform the mapping. In this paper a new server-based ARP extension (smartARP) is proposed, which allows the extension of ARP functionality beyond a single MAC layer broadcast domain. Compared to regular IP router, smartARP together with simple broadcast-filtering switches presents a low-cost alternative for forwarding packets between MAC layer broadcast domains. SmartARP is transparent to existing IP hosts, operates independent of LAN speed, and scales for big networks.

Demokracja i wartości w wychowaniu. O epistemologicznym statusie doświadczenia w pragmatyzmie

2019

Znaczenie doświadczenia w wychowaniu w postulatach pedagogiki pragmatyzmu jest powszechnie znane. Wiele miejsca tej problematyce poświęcił John Dewey. Celem artykułu jest odpowiedź na pytanie o ograniczenia w wykorzystywaniu doświadczenia w procesie wychowania. Odpowiedź na to pytanie jest wpisana w epistemologiczne zagadnienie relacji między doświadczeniem a teorią. W pierwszym punkcie są przywołane najważniejsze kwestie dotyczące pojęć doświadczenia, demokracji i wartości w wychowaniu. W drugim punkcie opisana jest rola doświadczenia w pragmatyzmie w kontekście behawioryzmu, zwłaszcza behawioryzmu społecznego. W trzecim punkcie przedstawione są w skrócie epistemologiczne dyskusje nad stat…