Search results for "ADE"

showing 10 items of 15269 documents

111-Indium-DTPA-Octreotid-Szintigraphie bei kolorektalen Lebermetastasen

1997

The somatostatin analogue octreotide is effective in the treatment of neuroendocrine and other tumours. 111-In-labelled DTPA-octreotide scintigraphy is successful in localizing primary neuroendocrine tumours and metastases and other tumours containing somatostatin receptors. An antiproliferative effect of octreotide was also demonstrated for colorectal carcinoma. Since only about 40% of colorectal carcinomas express somatostatin receptors, we tried to establish whether 111-In-labelled DTPA-octreotide scintigraphy is able to reveal the receptor status of liver metastases in patients with colorectal liver metastases. This would be useful in selecting patients for adjuvant therapy studies with…

medicine.medical_specialtymedicine.diagnostic_testSomatostatin receptorbusiness.industryOctreotidemedicine.diseaseScintigraphyGastroenterologySomatostatinInternal medicineCarcinomamedicineAdjuvant therapyAdenocarcinomaSurgerybusinessmedicine.drugSomatostatin Receptor PositiveLangenbeck's Archives of Surgery
researchProduct

Complete biochemical control and pituitary adenoma disappearance in a child with gigantism: Efficacy of octreotide therapy

2011

medicine.medical_specialtymedicine.diagnostic_testbusiness.industryEndocrinology Diabetes and MetabolismTreatment outcomeOctreotideMagnetic resonance imagingmedicine.diseaseGastroenterologyGigantismSettore MED/13 - EndocrinologiaRemission inductionEndocrinologyEndocrinologygigantism octreotidePituitary adenomaInternal medicineMedicinebusinessmedicine.drug
researchProduct

The "neurologic hypothesis": A new concept in the pathogenesis of the endometriosis?

2005

To cartograph the retroperitoneal infiltration of deep-infiltrating endometriosis of the rectovaginal space, we report on 467 patients who underwent laparoscopic/vaginal surgery for deep-infiltrating adenomyosis of the rectovaginal space. Exact localisation of the locoregional extension and of secondary infiltrating localisation where noted. The cervix and the rectovaginal ligament were mostly involved, while isolated lesions of the rectovaginal space were very rare. Comparisons of the most involved sites show an absolute correlation with the anatomical repartition of the pelvic sympathetic nervous system. We postulate a new "neurologic theory" which could be one more explanation for the de…

medicine.medical_specialtymedicine.diagnostic_testbusiness.industryEndometriosisEndometriosisLaparoscopic-vaginal surgeryObstetrics and GynecologyInterventional radiologymedicine.diseaseEndometriosis; Laparoscopic-vaginal surgery; Sympathetic nerve systemSurgerySympathetic nerve systemmedicine.anatomical_structurePeritoneumObstetrics and gynaecologySurgical oncologyLigamentMedicineSurgeryAdenomyosisRadiologyEndometriosibusinessCervix
researchProduct

Sa1459 FICE Endoscopy Diagnostic Accuracy by Applying OLGA and OLGIM Systems

2015

medicine.medical_specialtymedicine.diagnostic_testbusiness.industryGastroenterologyDiagnostic accuracyImage enhancementmedicine.diseaseEndoscopyMetaplasiaBiopsymedicineAdenocarcinomaRadiology Nuclear Medicine and imagingRadiologymedicine.symptombusinessGastrointestinal Endoscopy
researchProduct

Spiral-Computertomographie der Mamma

1994

Aim To evaluate the use of spiral CT in the diagnosis of breast lesions. Material and methods 93 female patients with suspicious or uncertain mammographic findings were examined by CT before and after contrast enhancement according to the following practical method: table movement, 6 mm/s, slice thickness 6 mm, increment 4 mm, contrast 200 ml, injection rate 3 ml/s, scan start 50 s after the beginning of the injection. Histological confirmation was present in 85 patients. Results All 44 invasive carcinomas were recognised. They were characterised by intensive focal contrast uptake. Only 2 out of 7 intraductal carcinomas were not shown by CT. 36 out of 38 benign lesions were correctly diagno…

medicine.medical_specialtymedicine.diagnostic_testbusiness.industryMammary glandmedicine.diseaseFibroadenomamedicine.anatomical_structuremedicineCarcinomaAdenocarcinomaMammographyRadiology Nuclear Medicine and imagingTomographyRadiologySpiral ctbusinessSpiralRöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren
researchProduct

Chylous ascites after lymphadenectomy for gynecological malignancies

2016

Background and Objectives Chylous ascites, an accumulation of milky-white lymph fluid in the peritoneal cavity, is a rare complication following retroperitoneal lymphadenectomy. This study evaluated the appearance and management of chylous ascites following lymphadenectomy for gynecological malignancies. Methods A total of 931 patients who underwent lymphadenectomy for gynecological malignancies at Erlangen University Hospital between 2002 and 2013 were reviewed retrospectively. Results Chylous ascites occurred postoperatively in 28 of the 931 patients (3.0%). All patients with chylous ascites had undergone combined systematic para-aortic and pelvic lymphadenectomy (SAPL). Patients with chy…

medicine.medical_specialtymedicine.diagnostic_testbusiness.industrymedicine.medical_treatmentRetrospective cohort studyGeneral Medicinemedicine.diseaseSurgery03 medical and health sciencesPeritoneal cavity0302 clinical medicinemedicine.anatomical_structureOncology030220 oncology & carcinogenesisChylous ascitesCarcinomamedicine030211 gastroenterology & hepatologySurgeryLymphadenectomyLymphComplicationbusinessLaparoscopyJournal of Surgical Oncology
researchProduct

Role of urokinase-type plasminogen activator (uPA) and plasminogen activator inhibitor type 1 (PAI-1) for prognosis in endometrial cancer

2007

Abstract Background. Urokinase-type plasminogen activator (uPA) and plasminogen activator inhibitor type 1 (PAI-1) contribute to the invasiveness of many carcinomas. Here, we studied a possible association between cytosolic uPA and PA-1 concentrations in tumor tissue with prognosis in patients with endometrial cancer. Methods. Cytosolic concentrations of uPA and PAI-1 were determined in 69 primary endothelial adenocarcinomas using an enzyme-linked immunoassay (ELISA). A possible influence of uPA and PAI-1 was studied by multivariate Cox regression adjusting for the established clinical prognostic factors FIGO-stage, grading, depth of invasion, diabetes mellitus and age. Results. Both uPA ( …

medicine.medical_specialtymedicine.drug_classAdenocarcinomaDisease-Free SurvivalMetastasisPredictive Value of TestsGermanyInternal medicineDiabetes mellitusPlasminogen Activator Inhibitor 1Progesterone receptorBiomarkers TumormedicineHumansNeoplasm StagingUrokinasebusiness.industryProportional hazards modelEndometrial cancerObstetrics and GynecologyMiddle AgedPrognosismedicine.diseaseSurvival AnalysisUrokinase-Type Plasminogen ActivatorEndometrial NeoplasmsEndocrinologyOncologyEstrogenFemalebusinessPlasminogen activatormedicine.drugGynecologic Oncology
researchProduct

A conservative treatment for chronic obstructive sialoadenitis by intraductal instillation of mucolytic, steroids and antibiotic solution

2021

Abstract Purposes Reporting our experience in treating chronic obstructive sialadenitis with a protocol consisting of sialoendoscopy and intraductal instillation of antibiotics, steroids and n-acetyl-cysteine (NAC) solution. Methods Prospective study of patients with chronic obstructive sialadenitis with no apparent lithiasic obstructions, with recurrent non-lithiasic sialoadenitis and patients with lithiasic sialoadenitis not solved with sialoendoscopy. In all cases, a sialoendoscopy was performed. All the patients affected by lithiasic sialoadenitis where the chronic inflammation was resolved with sialoendoscopy were excluded from the study. The mid-term follow-up was performed at 12 mont…

medicine.medical_specialtymedicine.drug_classAntibioticsConservative TreatmentIntraductal instillationSialadenitisChronic obstructive sialadenitismedicineHumansProspective StudiesSialoendoscopyProspective cohort studyExpectorantsbusiness.industryEndoscopyGeneral Medicinemedicine.diseaseSialadenitisSurgeryMiscellaneousAnti-Bacterial AgentsConservative treatmentOtorhinolaryngologyOtorhinolaryngologySialoendoscopyBetamethasoneSteroidsNeurosurgerybusinessmedicine.drug
researchProduct

Anti-inflammatory effects of zinc in PMA-treated human gingival fibroblast cells

2015

Objectives: Abnormal cellular immune response has been considered to be responsible for oral lesions in recurrent aphthous stomatitis. Zinc has been known to be an essential nutrient metal that is necessary for a broad range of biological activities including antioxidant, immune mediator, and anti-inflammatory drugs in oral mucosal disease. The objective of this study was to investigate the effects of zinc in a phorbol-12-myristate-13-acetate (PMA)-treated inflammatory model on human gingival fibroblast cells (hGFs). Study Design: Cells were pre-treated with zinc chloride, followed by PMA in hGFs. The effects were assessed on cell viability, cyclooxygenease-1,2(COX-1/2) protein expression, …

medicine.medical_specialtymedicine.drug_classmedicine.medical_treatmentGingivachemistry.chemical_elementOdontologíaInflammationZincPharmacologyRecurrent aphthous stomatitisAnti-inflammatoryImmune systemInternal medicinemedicineHumansViability assayGeneral DentistryCells CulturedInflammationOral Medicine and PathologyChemistryResearchFibroblasts:CIENCIAS MÉDICAS [UNESCO]Ciencias de la saludZincCytokineEndocrinologyOtorhinolaryngologyTetradecanoylphorbol AcetateUNESCO::CIENCIAS MÉDICASCytokinesTetradecanoylphorbol AcetateSurgerymedicine.symptomMedicina Oral, Patología Oral y Cirugía Bucal
researchProduct

Mirizzi syndrome in a patient with partial gastrectomy with Billroth II anastomosis: A case report

2020

Highlights • Obstructive jaundice may be a challenge for differential diagnosis. • Mirizzi Syndrome may simulate clinical and radiological presentation of common bile duct stones. • ERCP hardly achieves cannulation of biliary duct in altered anatomy, so gastroscope may be a correct choice in these cases. • Surgical treatment is essential in Mirizzi Syndrome.

medicine.medical_specialtymedicine.medical_treatment03 medical and health sciencesERCP0302 clinical medicineCholangiographyGastrectomyCase reportmedicineBillroth IBillroth IIEndoscopic retrograde cholangiopancreatographymedicine.diagnostic_testCommon bile ductbusiness.industryGallbladderMirizzi syndromemedicine.anatomical_structure030220 oncology & carcinogenesisCystic duct030211 gastroenterology & hepatologySurgeryGastrectomyLaparoscopyRadiologybusinessBillrothCholangiographyInternational Journal of Surgery Case Reports
researchProduct