Search results for "ADE"

showing 10 items of 15269 documents

Phylogeographical diversity of Anaplasma phagocytophilum in the Asian part of Russia based on multilocus sequence typing and analysis of the ankA gene

2019

Anaplasma phagocytophilum is a tick-transmitted bacterium that replicates in neutrophil granulocytes and elicits febrile disease in humans and animals; it is widely distributed in the Americas, Europe, Africa, and Asia. A. phagocytophilum is commonly regarded as a single species, but several genetic variants with distinct host distribution and geographical origin have been described. In a previous study, we used multilocus sequence typing (MLST) to characterize 25 A. phagocytophilum strains from Ixodes spp. ticks collected in the Asian part of Russia. The obtained concatenated sequences formed two separate clades reflecting their Asiatic origin and/or the vector species. As one of the clade…

0301 basic medicineMicrobiology (medical)030106 microbiologyBiologyIxodes persulcatusPolymerase Chain ReactionMicrobiologyRussia03 medical and health sciencesparasitic diseasesGeneticsAnimalsTypingGeography MedicalCladeMolecular BiologyAllelesPhylogenyEcology Evolution Behavior and SystematicsEhrlichiosisbacterial infections and mycosesbiology.organism_classificationAnaplasma phagocytophilumPhylogeography030104 developmental biologyInfectious DiseasesGenes BacterialEvolutionary biologyVector (epidemiology)Multilocus sequence typingVoleIxodesAnaplasma phagocytophilumMultilocus Sequence TypingInfection, Genetics and Evolution
researchProduct

Eighteen-Year Farming Management Moderately Shapes the Soil Microbial Community Structure but Promotes Habitat-Specific Taxa

2018

Soil microbes have critical influence on the productivity and sustainability of agricultural ecosystems, yet the magnitude and direction to which management practices affect the soil microbial community remain unclear. This work aimed to examine the impacts of three farming systems, conventional grain cropping (CON), organic grain cropping (ORG), and grain cropping-pasture rotation (ICL), on the soil microbial community structure and putative gene abundances of N transformations using high-throughput 16S rRNA gene and ITS sequencing approaches. Two additional systems, a forest plantation (PF) and an abandoned agricultural field subject to natural succession (SUC), were also included for bet…

0301 basic medicineMicrobiology (medical)Biodiversitylcsh:QR1-502PastureMicrobiologylcsh:MicrobiologyActinobacteria03 medical and health sciencesorganic farmingSoil pHGemmatimonadetesOriginal Researchgeographygeography.geographical_feature_categorybiologyEcologyPICRUStbiology.organism_classificationpasture030104 developmental biologyMicrobial population biologywoody plant systemOrganic farming16S rRNA geneITSAcidobacteriaFrontiers in Microbiology
researchProduct

GET_PHYLOMARKERS, a software package to select optimal orthologous clusters for phylogenomics and inferring pan-genome phylogenies, used for a critic…

2018

22 Pags.- 3 Tabls.- 7 Figs. Creative Commons License Attribution 4.0 International (CC BY 4.0).

0301 basic medicineMicrobiology (medical)Computer science030106 microbiologylcsh:QR1-502GenomicsLocus (genetics)Context (language use)Computational biologyMicrobiologyGenomelcsh:Microbiologylaw.invention03 medical and health scienceschemistry.chemical_compoundPhylogeneticslawPhylogenomicsRefSeqSpecies delimitationNucleotideCladeMexicoOriginal Researchchemistry.chemical_classificationPhylogenetic treespecies-treePan-genomeStenotrophomonas maltophilia complexgenome-phylogenyphylogenetics030104 developmental biologychemistryMolecular phylogeneticsRecombinant DNAmaximum-likelihoodDNA
researchProduct

A New Phylogenetic Framework for the Animal-adaptedMycobacterium tuberculosisComplex

2018

Tuberculosis (TB) affects humans and other animals and is caused by bacteria from the Mycobacterium tuberculosis complex (MTBC). Previous studies have shown that there are at least nine members of the MTBC infecting animals other than humans; these have also been referred to as ecotypes. However, the ecology and the evolution of these animal-adapted MTBC ecotypes are poorly understood. Here we screened 12,886 publicly available MTBC genomes and newly sequenced 17 animal-adapted MTBC strains, gathering a total of 529 genomes of animal-adapted MTBC strains. Phylogenomic and comparative analyses confirm that the animal-adapted MTBC members are paraphyletic with some members more closely relate…

0301 basic medicineMicrobiology (medical)Host–pathogen interactionsLineage (evolution)Populationlcsh:QR1-502specificityhost rangeHost tropismMicrobiologyGenetic diversitylcsh:Microbiology03 medical and health sciencesPhylogenomicseducationClade030304 developmental biologyWhole-genome sequencing0303 health scienceseducation.field_of_studybiologyPhylogenetic tree030306 microbiologygenetic diversitybiology.organism_classification3. Good health030104 developmental biologyhost–pathogen interactions; specificity; host range; genetic diversity; whole-genome sequencingMycobacterium tuberculosis complexwhole-genome sequencingEvolutionary biologyHost rangeSpecificityMycobacterium africanumhost–pathogen interactions
researchProduct

The clinical impact of PCR‐based point‐of‐care diagnostic in respiratory tract infections in children

2020

Abstract Background Children are commonly affected by respiratory tract infections. Based on clinical symptoms, laboratory evaluation, and imaging, the causative pathogen often cannot be delineated. Point‐of‐care‐testing systems that provide an opportunity for fast detection of common viruses and some bacteria can therefore influence treatment's options. We aimed to examine whether the Biofire® FilmArray® has an effect on antibiotic treatment, duration of antibiotic therapy, and length of hospital stay within a pediatric cohort. Methods We included children who were admitted to inpatient treatment with an acute respiratory tract infection from 02/2017 to 04/2018 using the FA respiratory pan…

0301 basic medicineMicrobiology (medical)Malemedicine.medical_specialtyPathogen detectionAdolescentmedicine.drug_classPoint-of-care testingPoint-of-Care SystemsAntibioticsClinical BiochemistryAdenovirus Infections Human03 medical and health sciences0302 clinical medicineInternal medicinepoint‐of‐care‐testingMedicineImmunology and AllergyHumansChildAcute respiratory tract infectionRespiratory Tract InfectionsResearch ArticlesPoint of careBiochemistry medicalPast medical historyRespiratory tract infectionsbusiness.industryBiofire® FilmArray®acute respiratory tract infectionsBiochemistry (medical)Public Health Environmental and Occupational HealthInfantHematologyLength of StayAnti-Bacterial AgentsMedical Laboratory Technology030104 developmental biology030220 oncology & carcinogenesisCase-Control StudiesChild PreschoolCohortantibiotic treatmentmultiplex RT‐PCRFemalebusinessMultiplex Polymerase Chain ReactionResearch ArticleJournal of Clinical Laboratory Analysis
researchProduct

Reconstruction of Diverse Verrucomicrobial Genomes from Metagenome Datasets of Freshwater Reservoirs

2017

The phylum Verrucomicrobia contains freshwater representatives which remain poorly studied at the genomic, taxonomic, and ecological levels. In this work we present eighteen new reconstructed verrucomicrobial genomes from two freshwater reservoirs located close to each other (Tous and Amadorio, Spain). These metagenomeassembled genomes (MAGs) display a remarkable taxonomic diversity inside the phylum and comprise wide ranges of estimated genome sizes (from 1.8 to 6 Mb). Among all Verrucomicrobia studied we found some of the smallest genomes of the Spartobacteria and Opitutae classes described so far. Some of the Opitutae family MAGs were small, cosmopolitan, with a general heterotrophic met…

0301 basic medicineMicrobiology (medical)Range (biology)030106 microbiologylcsh:QR1-502BiologyMicrobiologyGenomelcsh:Microbiology579 - Microbiología03 medical and health sciencesgenome streamliningCopiotrophfreshwater VerrucomicrobiaCladeGeneOriginal ResearchGeneticsmetagenomicsPhylumVerrucomicrobiabiology.organism_classification030104 developmental biologyrhodopsinMetagenomicsEvolutionary biologynitrogen fixationFrontiers in Microbiology
researchProduct

Using GFP-Tagged Escherichia coli to Investigate the Persistence of Fecal Bacteria in Vegetated Wetlands: An Experimental Approach

2020

The contamination of surface water by pathogenic bacteria of human origin is an important public health issue. Wetlands can be contaminated with fecal bacteria by water originating from different sources, such as wastewater treatment plants and agriculture. Escherichia coli is a commensal of the human gut flora and the major indication of fecal contamination in surface water. Little is known about the association between fecal bacteria and submerged macrophytes and how this may influence the water quality. We questioned whether macrophytes enhance or inhibit the bacterial growth in wetlands. For this purpose, we grew four different species of macrophytes (Mentha aquatica, Baldellia ranuncul…

0301 basic medicineMicrobiology (medical)antimicrobial compoundantimicrobial compounds[SDE.MCG]Environmental Sciences/Global ChangesElodea canadensisWetland010501 environmental sciencesmedicine.disease_causeGFP01 natural sciencesBiochemistryMicrobiologywetlands03 medical and health sciencesAquatic plantBotanymedicineEscherichia coliPharmacology (medical)General Pharmacology Toxicology and PharmaceuticsEscherichia coliComputingMilieux_MISCELLANEOUS0105 earth and related environmental sciences[SDV.EE]Life Sciences [q-bio]/Ecology environmentgeographymacrophytegeography.geographical_feature_categorybiology<i>Escherichia coli</i>lcsh:RM1-950food and beverages15. Life on landbiology.organism_classification6. Clean waterSparganium emersumwetlandMacrophytemacrophytesFecal coliform030104 developmental biologyInfectious Diseaseslcsh:Therapeutics. Pharmacology[SDV.MP]Life Sciences [q-bio]/Microbiology and Parasitologyfecal bacteriaWater quality
researchProduct

Endophytic Bacterial Community Structure and Function of Herbaceous Plants From Petroleum Hydrocarbon Contaminated and Non-contaminated Sites

2018

Bacterial endophytes (BEs) are non-pathogenic residents of healthy plant tissues that can confer benefits to plants. Many Bacterial endophytes have been shown to contribute to plant growth and health, alleviation of plant stress and to in-planta contaminant-degradation. This study examined the endophytic bacterial communities of plants growing abundantly in a heavily hydrocarbon contaminated site, and compared them to those found in the same species at a non-contaminated. We used culture- dependent and independent methods to characterize the community structure, hydrocarbon degrading capabilities, and plant growth promoting traits of cultivable endophytes isolated from Achillea millefolium,…

0301 basic medicineMicrobiology (medical)bacterial endophytesoil fieldlcsh:QR1-502Solidago canadensisMicrobiologyplant growth promoting bacterialcsh:Microbiology03 medical and health sciencesBotanyOriginal Research2. Zero hungerstem endosphereAchillea millefoliumbiologyPantoeafungiCommunity structurefood and beveragesContaminationHerbaceous plant16S ribosomal RNAbiology.organism_classificationplant microbiome030104 developmental biologyDaucus carotahydrocarbon degradationFrontiers in Microbiology
researchProduct

Psammomatoid Calcification-Rich Oncocytic Thyroid Adenoma With Clear-Cell Change

2018

Abundant calcifications and clear-cell change may occur in oncocytic thyroid adenoma (OTA). We aimed to report the features of a case of OTA peculiar by the presence of extensive calcifications and of a clear-cell component. The OTA was detected on a right thyroid lobectomy specimen. Clear-cell change was observed in 15%-20% of the cells. Numerous, focally confluent psammomatoid calcifications, resulting in macrocalcifications, were identified. The nodule cells, uni- or multinucleated oncocytes, including those with clear cytoplasm, expressed heterogeneously TTF1, S100 protein, Bcl2, CD10, as well as CD138 and CD56. Lipid-droplet markers adipophilin and TIP47 were also expressed. In conclus…

0301 basic medicineMicrobiology (medical)oncocytePathologymedicine.medical_specialtyHistologyAdenomanoduleOncocytePathology and Forensic Medicineclear cellcalcification03 medical and health sciences0302 clinical medicinehemic and lymphatic diseasesmedicinelcsh:PathologyThyroidbusiness.industryThyroid adenomaThyroidNodule (medicine)medicine.diseasepsammomatoid/psammoma-like/pseudo-psammomamitochondria030104 developmental biologymedicine.anatomical_structure030220 oncology & carcinogenesisimmunohistochemistryCommentaryImmunohistochemistryadenomamedicine.symptombusinessClear cellCalcificationlcsh:RB1-214Clinical Pathology
researchProduct

The malate sensing two-component system MaeKR is a non-canonical class of sensory complex for C4-dicarboxylates

2017

16 páginas, 7 figuras, 2 tablas

0301 basic medicineModels MolecularAdenosine Triphosphate / metabolismProtein ConformationScienceMalatesBacterial proteins/chemistry/metabolism/geneticsPlasma protein bindingBiologyModels BiologicalArticleConserved sequence03 medical and health sciencesAdenosine TriphosphateBacterial ProteinsAdenosine Triphosphate / chemistryDicarboxylic AcidsProtein Interaction Domains and MotifsAmino Acid SequenceKinase activityPhosphorylationLactobacilus cassei/classification/physiologyMalates/metabolismPromoter Regions GeneticConserved SequencePhylogenyMultidisciplinaryQAutophosphorylationfungiRTwo-component regulatory systemResponse regulatorLacticaseibacillus casei030104 developmental biologyBiochemistryMedicineModelsbiologica/moleculPhosphorylationCconserved secuenceProtein MultimerizationBinding domainProtein BindingScientific Reports
researchProduct