Search results for "ADOLESCENCE"

showing 10 items of 376 documents

Adolescent Exposure to the Synthetic Cannabinoid WIN 55212-2 Modifies Cocaine Withdrawal Symptoms in Adult Mice

2017

Chronic cannabinoid consumption is an increasingly common behavior among teenagers and has been shown to cause long-lasting neurobehavioral alterations. Besides, it has been demonstrated that cocaine addiction in adulthood is highly correlated with cannabis abuse during adolescence. Cocaine consumption and subsequent abstinence from it can cause psychiatric symptoms, such as psychosis, cognitive impairment, anxiety, and depression. The aim of the present research was to study the consequences of adolescent exposure to cannabis on the psychiatric-like effects promoted by cocaine withdrawal in adult mice. We pre-treated juvenile mice with the cannabinoid CB1 receptor agonist WIN 55212-2 (WIN)…

MalecannabisCannabinoid receptormedicine.medical_treatment0302 clinical medicineCocaineDopamine Uptake InhibitorsReceptor Cannabinoid CB1Spectroscopymedia_commoncocaine withdrawalBehavior Animalbiologyadolescence; cannabis; WIN 55212-2; cocaine withdrawal; miceGeneral MedicineSubstance Withdrawal SyndromeComputer Science ApplicationsHindlimb SuspensionElevated plus mazePsychosismedicine.medical_specialtymiceMorpholinesmedia_common.quotation_subjectNaphthalenesArticleCatalysisInorganic ChemistryCocaine-Related Disorders03 medical and health sciencesMemoryInternal medicinemedicineAnimalsWIN 55212-2Physical and Theoretical ChemistryPsychiatryMolecular BiologyCannabinoid Receptor Agonistsbusiness.industryAddictionOrganic ChemistryAbstinencemedicine.diseasebiology.organism_classificationBenzoxazines030227 psychiatryEndocrinologyAnxiogenicExploratory BehavioradolescenceCannabisCannabinoidbusiness030217 neurology & neurosurgeryInternational Journal of Molecular Sciences
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Influence of beliefs about romantic love on the justification of abusive behaviors among early adolescents

2021

Introduction Romantic experiences during adolescence have an important influence on functioning later in life. Romantic love has been associated with the acceptance of abusive behaviors. This study examined the relationship between myths of romantic love and the perceived severity of different types of abusive behaviors, as well as the influence of gender. Methods The sample comprised 448 Spanish adolescents (M = 12.92 years old; SD = 0.85), of which 50.3% were male and 49.7% were female. Participants were evaluated in the school setting. The Perception of Abuse Scale and the Myths, Fallacies, and Misconceptions about Romantic Love Scale were administered. Results Statistically significant …

Maleearly adolescenceAdolescentSocial Psychologymedia_common.quotation_subjectJealousyIntimate Partner Violencedating violenceromantic loveabusive behaviorsDevelopmental psychologyJealousyIntervention (counseling)PerceptionDevelopmental and Educational PsychologyHumansInterpersonal RelationsChildmedia_commonPerspective (graphical)CognitionMythologyPossession (law)perceived severityLoveRomancehumanitiesAggressionPsychiatry and Mental healthgender differencesPediatrics Perinatology and Child HealthFemalePsychology
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Sport disciplines, types of sports, and waist circumference in young adulthood – a population-based twin study

2017

Purpose: The benefits of physical activity (PA) in preventing abdominal obesity are well recognized, but the role of different sport disciplines remains open. We aimed, therefore, to investigate how participation in different sport disciplines, and the number and types of sports engaged in are associated with waist circumference (WC) in young adulthood. Methods: This population-based cohort study comprised 4027 Finnish twin individuals (1874 men), with a mean age of 34 y (32-37), who answered a survey, including self-measured WC. We extracted the number and identified the types (aerobic, power, and mixed) of the different sport disciplines respondents reported participating in. Results: The…

MaleliikuntaCohort Studies0302 clinical medicineOrthopedics and Sports Medicine030212 general & internal medicinetwin study315 Sport and fitness sciencesYoung adultta315Abdominal obesityRISKeducation.field_of_studyta3141General Medicinewaist circumference3142 Public health care science environmental and occupational healthsport disciplinesWEIGHT-GAINVISCERAL FATADOLESCENCEFemaleHEALTHmedicine.symptomfyysinen aktiivisuusSportsCohort studyAdultCOUNTRIESmedicine.medical_specialtyWaistDizygotic twinPopulationEXERCISE030209 endocrinology & metabolismPhysical Therapy Sports Therapy and Rehabilitationabdominal obesityTIME PHYSICAL-ACTIVITY03 medical and health sciencesmedicineHumanseducationkaksostutkimusPhysical activitybusiness.industryTwin studyBODY-MASS INDEXPhysical therapybusinesshuman activitiesBody mass indexDemographyEuropean Journal of Sport Science
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In utero Δ9-tetrahydrocannabinol exposure confers vulnerability towards cognitive impairments and alcohol drinking in the adolescent offspring: Is th…

2020

Background:Cannabinoid consumption during pregnancy has been increasing on the wave of the broad-based legalisation of cannabis in Western countries, raising concern about the putative detrimental outcomes on foetal neurodevelopment. Indeed, since the endocannabinoid system regulates synaptic plasticity, emotional and cognitive processes from early stages of life interfering with it and other excitability endogenous modulators, such as neuropeptide Y (NPY), might contribute to the occurrence of a vulnerable phenotype later in life.Aims:This research investigated whether in utero exposure to Δ9-tetrahydrocannabinol (THC) may induce deficits in emotional/cognitive processes and alcohol vulner…

Malelimbic memoryAlcohol Drinkingmedicine.medical_treatmentVulnerabilityPhysiologyAlcoholMotor ActivityConflict Psychological03 medical and health scienceschemistry.chemical_compound0302 clinical medicineMemoryPregnancymental disordersMedicineAnimalsPharmacology (medical)Cognitive DysfunctionNeuropeptide YPrenatal THCDronabinolRats Wistarinstrumental learningPharmacologyPregnancybiologyBehavior Animalbusiness.industryBrainCognitionalcohol vulnerabilitybiology.organism_classificationmedicine.diseaseNeuropeptide Y receptor030227 psychiatryRatsPsychiatry and Mental healthchemistryIn uteroPrenatal Exposure Delayed EffectsSettore BIO/14 - FarmacologiaadolescenceFemaleCannabisCannabinoidbusiness030217 neurology & neurosurgeryJournal of psychopharmacology (Oxford, England)
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Development of Children’s Actual and Perceived Motor Competence, Cardiorespiratory Fitness, Physical Activity, and BMI

2021

Purpose To examine synergistic associations between developmental trajectories of motor competence, perceived motor competence, cardiorespiratory fitness, moderate-to-vigorous physical activity (MVPA), and body mass index (BMI) from late childhood to adolescence. Methods In this 3-yr follow-up study, motor competence, perceived motor competence, cardiorespiratory fitness, MVPA, and BMI were assessed in 1167 Finnish school-age children (girls = 583, boys = 565; Mage = 11.27 ± 0.33). Moderate-to-vigorous physical activity was measured using hip-mounted accelerometers. Developmental trajectories were analyzed using latent growth curve modeling. Results The development of motor competence, card…

MalelongitudinalPhysical activitylapset (ikäryhmät)Physical Therapy Sports Therapy and RehabilitationBody Mass IndexDevelopmental psychologyCompetence (law)Child Developmentlatent growth modelingmotorinen kehitysHumansOrthopedics and Sports MedicinepainoindeksiChildmotoriset taidotExerciseLatent growth modelingperson-oriented approachCardiorespiratory fitnessLate childhoodSelf Conceptfyysinen kuntoCardiorespiratory FitnessMotor SkillsPhysical activity decreasedFemaleadolescenceseurantatutkimusPsychologyBody mass indexfyysinen aktiivisuusFollow-Up StudiesMedicine & Science in Sports & Exercise
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Suicidal ideation in a community-derived sample of Spanish adolescents

2017

Introduction: Suicide is a current public health problem and among the main causes of mortality in adolescents and young adults. The main goal of this study was to analyse suicidal ideation in a representative sample of Spanish adolescents. Specifically, the prevalence rates of suicide ideation, the psychometric properties of the Paykel Suicide Scale (PSS) scores, and the socio-emotional adjustment of adolescents at risk for suicide were analysed. Material and methods: The sample consisted of 1,664 participants (M = 16.12 years, SD = 1.36, range 14-19 years), selected by stratified sampling by clusters. The instruments used were the PSS, the Strengths and Difficulties Questionnaire, the Per…

Malemedicine.medical_specialtyAdolescentPsychometricsPopulationPsychology AdolescentSuicide AttemptedEmotional AdjustmentSuicidal Ideation03 medical and health sciences0302 clinical medicineSuicidal ideationValidationmedicinePrevalenceHumansMeasurement invariance030212 general & internal medicineeducationSuicidal ideationPsychiatric Status Rating Scaleseducation.field_of_studyPublic healthLife satisfactionGeneral MedicineStrengths and Difficulties QuestionnaireMental health030227 psychiatryStratified samplingAdolescenceSuicideCross-Sectional StudiesSpainFemalemedicine.symptomPsychologySocial AdjustmentClinical psychology
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Intimate Partner Violence and Mental Health Among Italian Adolescents: Gender Similarities and Differences

2013

Only a few studies have analyzed the health impact of intimate partner violence (IPV) on male and female adolescents, taking into account other kinds of violence that can affect their health. In this study, 43.7% of female adolescents and 34.8% of males reported IPV; females reported more psychological and sexual IPV, with no differences for physical IPV. Controlling for family and sexual violence and other confounding factors, female adolescents exposed to IPV had significantly higher adjusted odds ratios (AORs) for depression, panic attacks, eating problems, and suicidal ideation. For male adolescents, only the OR of eating problems almost reached statistical significance.

Malemedicine.medical_specialtyAdolescentSociology and Political ScienceeducationPoison controlpartner violence; adolescence; sexual violence; depression; eating disorderssexual violenceeating disordersViolencebehavioral disciplines and activitiesSuicide preventionSuicidal IdeationFeeding and Eating DisordersGender StudiesSex Factorsmental disordersInjury preventionOdds RatiomedicineHumansInterpersonal RelationsPsychiatrySuicidal ideationCrime VictimsDepressive DisorderSexual violenceMental Disorderssocial sciencesmedicine.diseaseMental healthEating disordersMental HealthSexual PartnersItalyRapedepressionPanic Disorderpopulation characteristicsDomestic violenceFemaleadolescencemedicine.symptomPsychologyLawClinical psychologypartner violence
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Low back and neck and shoulder pain in members and non-members of adolescents' sports clubs : the Finnish Health Promoting Sports Club (FHPSC) study

2016

Background The objective of this study was to investigate the prevalence of self-reported low back pain (LBP) and neck and shoulder pain (NSP), and the related factors in members and non-members of adolescents’ sports clubs. Methods This cross-sectional study was based on surveys of 14–16-year-olds as a part of the Finnish Health Promoting Sports Club (FHPSC) Study. The surveys on self-reported health behaviours, injuries, and musculoskeletal health were conducted among sports club members (n = 962) and non-members (n = 675). Binary logistic regression analysis was applied to study the associations between dependent variables of LBP and NSP, and the independent factors. Results The prevalen…

Malemedicine.medical_specialtyAdolescentSports medicineCross-sectional studyshoulder painHealth Behaviorneck painprevalence03 medical and health sciencesScreen time0302 clinical medicineRheumatologyRisk FactorsShoulder PainEpidemiologyPrevalencemedicinesports club participationHumansLow back painOrthopedics and Sports Medicine030212 general & internal medicineFinlandlow back painSports club participationNeck painNeck Painbusiness.industryYouth Sports030229 sport sciencesOdds ratioLow back painNeck and shoulder painAdolescenceCross-Sectional StudiesAdolescent BehaviorPhysical therapypopulation characteristicsFemaleadolescenceClubmedicine.symptombusinesshuman activitiesResearch Article
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Adolescent binge‐ethanol accelerates cognitive impairment and β‐amyloid production and dysregulates endocannabinoid signaling in the hippocampus of A…

2019

Previous research in rodents suggests that the long‐term neurobehavioral disturbances induced by chronic ethanol (EtOH) exposure could be due to endocannabinoid system (ECS) alterations. Moreover, ECS failure has been proposed to mediate the cognitive impairment and β‐amyloid production in Alzheimer disease (AD). Thus, in the present study, we evaluated the effects of adolescent EtOH binge drinking on the cognitive disturbances, hippocampal β‐amyloid levels, and in the ECS expression on a transgenic mouse model (APP/PSEN, AZ) of AD. We exposed AZ and wild‐type mice to a binge‐drinking treatment during adolescence. At 6 and 12 months of age, we evaluated hippocampal‐dependent learning and me…

Malemedicine.medical_specialtyDiacylglycerol lipasehippocampusmedicine.medical_treatmentMedicine (miscellaneous)HippocampusMice TransgenicHippocampusBinge DrinkingMice03 medical and health sciences0302 clinical medicineAlzheimer DiseaseInternal medicinemental disordersGene expressionmedicineAnimalsCognitive DysfunctionPharmacologyAmyloid beta-PeptidesEthanolbiologyWild typeendocannabinoidmedicine.diseaseEndocannabinoid systembinge drinkingMonoacylglycerol Lipases030227 psychiatryMonoacylglycerol lipaseDisease Models AnimalPsychiatry and Mental healthEndocrinologybiology.proteinβ‐amyloidadolescenceFemaleCannabinoidAlzheimer diseaseAlzheimer's disease030217 neurology & neurosurgeryEndocannabinoidsSignal TransductionAddiction Biology
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Changes in histone acetylation in the prefrontal cortex of ethanol-exposed adolescent rats are associated with ethanol-induced place conditioning

2012

Alcohol drinking during adolescence can induce long-lasting effects on the motivation to consume alcohol. Abnormal plasticity in reward-related processes might contribute to the vulnerability of adolescents to drug addiction. We have shown that binge-like ethanol treatment in adolescent rats induces alterations in the dopaminergic system and causes histone modifications in brain reward regions. Considering that histone acetylation regulates transcriptional activity and contributes to drug-induced alterations in gene expression and behavior, we addressed the hypothesis that ethanol is capable of inducing transcriptional changes by histone modifications in specific gene promoters in adolescen…

Malemedicine.medical_specialtyPrefrontal CortexHDAC inhibitionChromatin remodelingHistonesCellular and Molecular Neurosciencechemistry.chemical_compoundInternal medicineConditioning PsychologicalmedicineAnimalsEpigeneticsRats WistarConditioned place aversionPharmacologyEthanolbiologyHistone modificationsAge FactorsAcetylationSodium butyrateRatsAdolescenceHistone Deacetylase InhibitorsHistoneEndocrinologychemistryBiochemistryAcetylationbiology.proteinBrain stimulation rewardBinge-like ethanol treatmentHistone deacetylaseFOSBNeuropharmacology
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