Search results for "ADR"

showing 10 items of 6304 documents

Pharmacological activation of CB2 receptors counteracts the deleterious effect of ethanol on cell proliferation in the main neurogenic zones of the a…

2015

Chronic alcohol exposure reduces endocannabinoid activity and disrupts adult neurogenesis in rodents, which results in structural and functional alterations. Cannabinoid receptor agonists promote adult neural progenitor cell (NPC) proliferation. We evaluated the protective effects of the selective CB1 receptor agonist ACEA, the selective CB2 receptor agonist JWH133 and the fatty-acid amide-hydrolase (FAAH) inhibitor URB597, which enhances endocannabinoid receptor activity, on NPC proliferation in rats with forced consumption of ethanol (10%) or sucrose liquid diets for 2 weeks. We performed immunohistochemical and stereological analyses of cells expressing the mitotic phosphorylation of his…

:Phenomena and Processes::Physiological Phenomena::Physiological Processes::Growth and Development::Morphogenesis::Embryonic and Fetal Development::Organogenesis::Neurogenesis [Medical Subject Headings]CB1 receptorTubulina (proteína)Cannabinoid receptorCarbamatosEtanol:Chemicals and Drugs::Amino Acids Peptides and Proteins::Proteins::Nuclear Proteins::Histones [Medical Subject Headings]Ventrículos lateralesSacarosaNeuronasSubgranular zone0302 clinical medicine:Chemicals and Drugs::Amino Acids Peptides and Proteins::Proteins::Membrane Proteins::Receptors Cell Surface::Receptors G-Protein-Coupled::Receptors Cannabinoid::Receptor Cannabinoid CB1 [Medical Subject Headings]Histonas:Chemicals and Drugs::Organic Chemicals::Carboxylic Acids::Acids Acyclic::Carbamates [Medical Subject Headings]Receptor cannabinoide CB1Cannabinoid receptor type 2:Organisms::Eukaryota::Animals [Medical Subject Headings]:Phenomena and Processes::Metabolic Phenomena::Metabolism::Phosphorylation [Medical Subject Headings]:Anatomy::Cells::Stem Cells::Neural Stem Cells [Medical Subject Headings]:Anatomy::Nervous System::Neurons [Medical Subject Headings]health care economics and organizations:Anatomy::Nervous System::Central Nervous System::Brain::Cerebral Ventricles::Lateral Ventricles [Medical Subject Headings]Original Research:Chemicals and Drugs::Nucleic Acids Nucleotides and Nucleosides::Nucleosides::Deoxyribonucleosides::Deoxyuridine::Bromodeoxyuridine [Medical Subject Headings]0303 health sciencesAlcoholismoalcoholConsumo de alcoholNeurogenesis:Phenomena and Processes::Genetic Phenomena::Phenotype::Genetic Markers [Medical Subject Headings]:Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Molecular Mechanisms of Pharmacological Action::Neurotransmitter Agents::Cannabinoid Receptor Modulators::Cannabinoid Receptor Agonists [Medical Subject Headings]Benzamidas:Chemicals and Drugs::Amino Acids Peptides and Proteins::Proteins::Membrane Proteins::Receptors Cell Surface::Receptors G-Protein-Coupled::Receptors Cannabinoid::Receptor Cannabinoid CB2 [Medical Subject Headings]Endocannabinoid system3. Good healthbromodesoxiuridinaneurogenesisEndocannabinoidesmedicine.anatomical_structure:Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Hydrolases [Medical Subject Headings]ACEADietaAlcoholFosforilaciónAgonistmedicine.medical_specialtyHidrolasasmedicine.drug_classNeurogenesiseducation:Psychiatry and Psychology::Mental Disorders::Substance-Related Disorders::Alcohol-Related Disorders::Alcoholism [Medical Subject Headings]Subventricular zoneBiology:Phenomena and Processes::Physiological Phenomena::Nutritional Physiological Phenomena::Diet [Medical Subject Headings]:Anatomy::Nervous System::Central Nervous System::Brain::Prosencephalon::Telencephalon::Cerebrum::Cerebral Cortex::Hippocampus::Dentate Gyrus [Medical Subject Headings]lcsh:RC321-57103 medical and health sciencesCellular and Molecular NeuroscienceRatasInternal medicine:Chemicals and Drugs::Amino Acids Peptides and Proteins::Proteins::Nerve Tissue Proteins::Tubulin [Medical Subject Headings]JWH133medicineGiro dentadolcsh:Neurosciences. Biological psychiatry. Neuropsychiatry030304 developmental biologyCélulas madre nerviosas:Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Molecular Mechanisms of Pharmacological Action::Neurotransmitter Agents::Endocannabinoids [Medical Subject Headings]Dentate gyrusmarcadores genéticosCB2 receptor:Chemicals and Drugs::Carbohydrates::Polysaccharides::Oligosaccharides::Disaccharides::Sucrose [Medical Subject Headings]:Anatomy::Nervous System::Central Nervous System::Brain::Prosencephalon::Diencephalon::Hypothalamus [Medical Subject Headings]:Chemicals and Drugs::Organic Chemicals::Alcohols::Ethanol [Medical Subject Headings]Endocrinology:Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Rats [Medical Subject Headings]nervous system:Psychiatry and Psychology::Behavior and Behavior Mechanisms::Behavior::Drinking Behavior::Alcohol Drinking [Medical Subject Headings]:Chemicals and Drugs::Organic Chemicals::Amides::Benzamides [Medical Subject Headings]030217 neurology & neurosurgeryHipotálamoNeuroscience
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Introduzione ai modelli di ADR, profili storico-comparatistici

2011

brevi cenni sul movimento ADR negli Stati uniti d'America dagli anni 50 ad oggi

ADR Stati Uniti diritto processoSettore IUS/02 - Diritto Privato Comparato
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INTERMEDIAZIONE DIGITALE E COMPOSIZIONE DELLE CONTROVERSIE: DALL’ALTERNATIVE DISPUTE RESOLUTION ALL’ALIEN DISPUTE RESOLUTION

2017

ADR, intermediazione digitale, accesso alla giustizia, e-commerce

ADR intermediazione digitale accesso alla giustizia e-commerce
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IL DIALOGO NELLA MEDIAZIONE E RISOLUZIONE DI CONFLITTI. APPROFONDIMENTI LINGUISTICI

2016

I paesi europei conoscono da tempo varie forme di mediazione e conciliazione. Pur nella diversità di metodologie e regole della mediazione presenti nei paesi membri, sono riscontrabili tratti comuni che tuttavia necessiterebbero di una regolamentazione univoca per tutto il territorio europeo. Il ruolo assunto dall’esperienza comunitaria in materia di conciliazione è assai rilevante, in quanto lo strumento della mediazione ha ricevuto un importante sviluppo grazie alle direttive europee aventi lo scopo di adeguare le legislazioni degli Stati membri in materia di Alternatitve Dispute Resolution (ADR), dapprima in materia societaria e commerciale, successivamente in materia di consumo e nei ra…

ADR mediazione approccio narrativo analisi linguistico-terminologica strategie comunicativeSettore L-LIN/12 - Lingua E Traduzione - Lingua Inglese
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The BRICS Centres of Dispute Resolution: causes, state of the art, and prospects

2023

The idea of an enhanced cooperation and exchange of knowledge and best practices among its member states in the fields of trade, commerce, and investments -among others- is at the heart of BRICS. In fact, intra-BRICS trade has nearly tripled over the last decade, supported by an increase in intra-regional trade for all member countries. Thanks to their influential and remarkable progress in promoting local currency (for de-dollarisation purposes), regional FDI, and regional trade, the BRICS economies have emerged and have taken a new space in the twenty-first century. This reinforced one of the core objectives pursued by BRICS which is that of enhancing the five developing economies’ role i…

ADRArbitrationBRICSDispute ResolutionSettore IUS/13 - Diritto Internazionale
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Acceso a la Justicia de los Consumidores a través del ADR y del ODR

2018

El avance de las tecnologías de información y la comunicación nos ha llevado a cambiar nuestra forma de relacionarnos tanto entre nosotros, como con las administraciones. Además, la adquisición de bienes de consumo a través del medio online es cada día más importante para en la economía global y doméstica. Todo ello, llevó a la Unión Europea a la creación del llamado Mercado Único Digital, donde se estableció como uno de los objetivos prioritarios mejorar la tutela efectiva de los ciudadanos comunitarios que realizan compras a través de internet. El presente trabajo tiene por objeto realizar un análisis sobre las facilidades y dificultades que encuentran los consumidores a la hora de accede…

ADRlegitimación colectiva consumidoresconciliaciónarbitraje de consumoACCESO A LA JUSTICIAresolución alternativa de conflictosconsumer alternative dispute resolutionlegitimación consumoderecho procesalsistema arbitral de consumoderecho de consumoconsumidoresODRonline dispute resolutionmediaciónresolución de conflictos onlineresolución de conflictos en línea
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La prevención, gestión y solución extrajudicial de conflictos en la empresa familiar

2020

La tesis doctoral aborda el ámbito conflictual de la empresa familiar y la posible implantación de los cauces alternativos extrajudiciales de resolución de conflictos. Partiendo de que los conflictos originados en la empresa familiar, por su especial idiosincrasia, no encuentran en la vía judicial el método idóneo para su gestión y solución, se estudian las distintas aplicaciones del arbitraje y la mediación en la empresa familiar, abordando su implementación, tanto en el ámbito preventivo, como de gestión y resolución de sus conflictos. Todo ello lleva en una última fase de la tesis doctoral a reflexionar acerca de la idoneidad de la mediación en la empresa familiar, como herramienta clave…

ADRmediaciónarbitrajeempresa familiar:CIENCIAS JURÍDICAS Y DERECHO [UNESCO]UNESCO::CIENCIAS JURÍDICAS Y DERECHOconflictos familiares
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Measurement of the branching ratio and an upper limit on

1995

Abstract Using 1.45 million hadronic Z decays collected by the ALEPH experiment at LEP, the b → τ − ν - τ X branching ratio is measured to be 2.75 ± 0.30 ± 0.37%. In addition an upper limit of 1.8 × 10 −3 at 90% confidence level is placed upon the exclusive branching ratio of B − → τ − ν - τ . These measurements are consistent with SM expectations, and put the constraint tan β M h ± GeV −1 at 90% confidence level on all Type II two Higgs doublet models (such as the MSSM).

ALEPH ExperimentNuclear physicsPhysicsNuclear and High Energy PhysicsBranching fractionElectron–positron annihilationHadronHiggs bosonLimit (mathematics)SupersymmetryALEPH experimentPhysics Letters B
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Heavy flavour decay muon production at forward rapidity in proton--proton collisions at sqrt(s) = 7 TeV

2012

The production of muons from heavy flavour decays is measured at forward rapidity in proton-proton collisions at $\sqrt{s} = 7$ TeV collected with the ALICE experiment at the LHC. The analysis is carried out on a data sample corresponding to an integrated luminosity $L_{\rm int} = 16.5$ nb$^{-1}$. The transverse momentum and rapidity differential production cross sections of muons from heavy flavour decays are measured in the rapidity range 2.5 < y < 4, over the transverse momentum range 2 < $p_{\rm T}$ < 12 GeV/$c$. The results are compared to predictions based on perturbative QCD calculations.

ALICE experiment; P-P collisions; Heavy flavour muon decayProtonAlicePhysics::Instrumentation and DetectorsHeavy flavour muon decayheavy flavour01 natural sciencesPp CollisionsSingle MuonsHigh Energy Physics - ExperimentHigh Energy Physics - Experiment (hep-ex)ALICEHeavy Flavour Production[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]Nuclear ExperimentAlice ExperimentALICE experiment; Heavy flavour production; LHC; Pp collisions; Single muons; Nuclear and High Energy PhysicsP-P collisionsQuantum chromodynamicsPhysicsLarge Hadron ColliderLuminosity (scattering theory)PhysicsProduction Cross-SectionPerturbative QCDP-P collisionP(P)Over-Bar CollisionsLHC ALICE experiment pp collisions Single muons Heavy flavour productionLHCLhcpp collisionsParticle Physics - ExperimentHeavy flavour productionParticle physicsNuclear and High Energy PhysicsLHC; ALICE; heavy flavourFOS: Physical sciencesalice experiment; pp collisions; heavy flavour production; single muons; lhcNuclear physicsmuon0103 physical sciencesALICE; heavy flavour; muonRapidity010306 general physicsHadron-CollisionsMuonta114Bottom-Quark Production010308 nuclear & particles physicsHigh Energy Physics::PhenomenologyALICE; LHC; CERN; strange particle; pp; 7 TeV; Heavy flavour production; Single muonsALICE experimentSingle muonsJ/Psi ProductionHigh Energy Physics::ExperimentLepton
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Metabolic signatures across the full spectrum of non-alcoholic fatty liver disease.

2022

Funder: European Commission

ALTtype 2 diabetes mellitusROC receiving operator characteristicaspartate aminotransferaseHSDLDL low-density lipoproteinUHPLC ultrahigh-performance liquid chromatographyROCHCCNon-alcoholic steatohepatitisGCPCANASHGastroenterology2-HB 2-hydroxybutanoic acid; 3-HB 3-hydroxybutanoic acid; ALT alanine aminotransferase; AST aspartate aminotransferase; CE cholesterol ester; Cer ceramide; FFA free fatty acid; FLIP Fatty Liver Inhibition of Progression; Fibrosis; GC gas chromatography; HCC hepatocellular carcinoma; HSD honest significant difference; LC lipid cluster; LDL low-density lipoprotein; LM lipid and metabolite; LMC lipid metabolite and clinical variable; LPC lysophosphatidylcholine; Lipidomics; Mass spectrometry; Metabolomics; NAFL non-alcoholic fatty liver; NAFLD non-alcoholic fatty liver disease; NAS NASH activity score; NASH non-alcoholic steatohepatitis; NIDDK NASH-CRN National Institute of Digestive Diseases and Kidney NASH Clinical Research Network; NRR non-rejection rate; Non-alcoholic steatohepatitis; PC(O) ether PC; PC phosphatidylcholine; PCA principal component analysis; PE phosphatidylethanolamine; QTOFMS quadrupole-time-of-flight mass spectrometry; ROC receiving operator characteristic; SAF steatosis activity and fibrosis; SM sphingomyelin; T2DM type 2 diabetes mellitus; TG triacylglycerol; UHPLC ultrahigh-performance liquid chromatographySAFSAF steatosis activity and fibrosisLM lipid and metabolitehonest significant differenceHSD honest significant differenceTG triacylglycerolnon-rejection ratecholesterol esterPCPEGC gas chromatographyfree fatty acidFLIPNASH non-alcoholic steatohepatitisNIDDK NASH-CRN National Institute of Digestive Diseases and Kidney NASH Clinical Research NetworkBIOMARKERST2DMPE phosphatidylethanolamineLDLlipidNAFLDFFA free fatty acid2-HBMetabolomicsNAFL non-alcoholic fatty liverLMCphosphatidylcholineScience & TechnologySM sphingomyelinGastroenterology & HepatologyMass spectrometryactivitynutritional and metabolic diseasesT2DM type 2 diabetes mellitusACIDSreceiving operator characteristicdigestive system diseasesquadrupole-time-of-flight mass spectrometryLC lipid clusterlow-density lipoproteinNAS2-HB 2-hydroxybutanoic acidNAS NASH activity scoreQTOFMSether PCNRRSCORING SYSTEMprincipal component analysisgas chromatographyLC2-hydroxybutanoic acidPROGRESSIONAST aspartate aminotransferaseLMPC phosphatidylcholinePC(O)MARKERSUHPLCsteatosisTOOLImmunology and AllergyINSULIN-RESISTANCECerSMFatty Liver Inhibition of Progressionhepatocellular carcinoma2-HB 2-hydroxybutanoic acid NIDDK NASH-CRN National Institute of Digestive Diseases and Kidney NASH Clinical Research Network NRR non-rejection rate Non-alcoholic steatohepatitis PC(O) ether PC PC phosphatidylcholine PCA principal component analysis PE phosphatidylethanolamine QTOFMS quadrupole-time-of-flight mass spectrometry ROC receiving operator characteristic SAF steatosis activity and fibrosis SM T2DM type 2 diabetes mellitus TG triacylglycerol UHPLC ultrahigh-performance liquid chromatographyultrahigh-performance liquid chromatographyCELPC3-HBNAFLnon-alcoholic fatty liverTGtriacylglycerolNRR non-rejection rateLife Sciences & BiomedicineNAFLD non-alcoholic fatty liver diseaseFLIP Fatty Liver Inhibition of Progressionalanine aminotransferasemetaboliteCer ceramideCE cholesterol estersphingomyelinlysophosphatidylcholineand fibrosisALT alanine aminotransferaseInternal MedicineceramideNational Institute of Digestive Diseases and Kidney NASH Clinical Research NetworkAST3-HB 3-hydroxybutanoic acidQTOFMS quadrupole-time-of-flight mass spectrometryPCA principal component analysisLPC lysophosphatidylcholineHepatologynon-alcoholic fatty liver diseaseand clinical variablePC(O) ether PC3-hydroxybutanoic acidFibrosisNASH activity scoreNIDDK NASH-CRNlipid clusterlipid and metabolitephosphatidylethanolamineLipidomicsLMC lipid metabolite and clinical variableFFAHCC hepatocellular carcinomaJHEP reports : innovation in hepatology
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