Search results for "ADR"
showing 10 items of 6304 documents
Regeneración de cartílago mediante el uso de células madre de pulpa dental humanas (hDPSCs)
2020
El tejido cartilaginoso es un tejido fundamental, puesto que proporciona sostén a nuestro organismo. Cuando el cartílago articular se lesiona experimenta una regeneración compleja y limitada. Por ello es importante buscar alternativas y ampliar las soluciones que se están utilizando actualmente para tratar enfermedades en las que se produce la alteración del cartílago articular, como la osteoartritis. Con la base en esta idea, recientemente la ingeniería tisular ha desarrollado distintas herramientas para tratar de regenerar el cartílago cuando la regeneración por otras vías no es posible. Dentro de las estrategias que existen, se ha potenciado el uso de hidrogeles combinados con condrocito…
Estudio del secretoma de las células madre de tejido adiposo y de péptidos PTHrP en células articulares osteoartríticas
2016
La osteoartritis (OA) es la patología articular más frecuente y la causa más importante de discapacidad en personas de edad avanzada. Existe un gran interés en el estudio de nuevas dianas terapéuticas que puedan facilitar la prevención o tratamiento de la OA, ya que actualmente no existe ningún tratamiento eficaz. En este trabajo, se han abordado dos posibles nuevas estrategias: el medio acondicionado (MA) de las células madre del tejido adiposo (ASCs) y los péptidos derivados de la proteína relacionada con la hormona paratiroidea (PTHrP). Las ASCs tienen un elevado potencial terapéutico. Numerosos estudios han mostrado que ejercen efectos beneficiosos en diferentes modelos de enfermedad a …
The strong coupling constant: State of the art and the decade ahead
2022
This document provides a comprehensive summary of the state-of-the-art, challenges, and prospects in the experimental and theoretical study of the strong coupling $\alpha_s$. The current status of the seven methods presently used to determine $\alpha_s$ based on: (i) lattice QCD, (ii) hadronic $\tau$ decays, (iii) deep-inelastic scattering and parton distribution functions fits, (iv) electroweak boson decays, hadronic final-states in (v) e+e-, (vi) e-p, and (vii) p-p collisions, and (viii) quarkonia decays and masses, are reviewed. Novel $\alpha_s$ determinations are discussed, as well as the averaging method used to obtain the PDG world-average value at the reference Z boson mass scale, $\…
First measurement of quarkonium polarization in nuclear collisions at the LHC
2021
The polarization of inclusive J/$\psi$ and $\Upsilon(1{\rm S})$ produced in Pb-Pb collisions at $\sqrt{s_{\rm{NN}}}=5.02$ TeV at the LHC is measured with the ALICE detector. The study is carried out by reconstructing the quarkonium through its decay to muon pairs in the rapidity region $2.5<y<4$ and measuring the polar and azimuthal angular distributions of the muons. The polarization parameters $\lambda_{\theta}$, $\lambda_{\phi}$ and $\lambda_{\theta\phi}$ are measured in the helicity and Collins-Soper reference frames, in the transverse momentum interval $2<p_{\rm T}<10$ GeV/$c$ and $p_{\rm T}<15$ GeV/$c$ for the J/$\psi$ and $\Upsilon(1{\rm S})$, respectively. The polarization parameter…
Multipion Bose-Einstein correlations in pp,p-Pb, and Pb-Pb collisions at energies available at the CERN Large Hadron Collider
2016
Three- and four-pion Bose-Einstein correlations are presented in pp, p-Pb, and Pb-Pb collisions at the LHC. We compare our measured four-pion correlations to the expectation derived from two- and three-pion measurements. Such a comparison provides a method to search for coherent pion emission. We also present mixed-charge correlations in order to demonstrate the effectiveness of several analysis procedures such as Coulomb corrections. Same-charge four-pion correlations in pp and p-Pb appear consistent with the expectations from three-pion measurements. However, the presence of non-negligible background correlations in both systems prevent a conclusive statement. In Pb-Pb collisions, we obse…
Performance of the ALICE experiment at the CERN LHC
2014
ALICE is the heavy-ion experiment at the CERN Large Hadron Collider. The experiment continuously took data during the first physics campaign of the machine from fall 2009 until early 2013, using proton and lead-ion beams. In this paper we describe the running environment and the data handling procedures, and discuss the performance of the ALICE detectors and analysis methods for various physics observables.
Measurement of the average shape of longitudinal profiles of cosmic-ray air showers at the Pierre Auger Observatory
2019
The profile of the longitudinal development of showers produced by ultra-high energy cosmic rays carries information related to the interaction properties of the primary particles with atmospheric nuclei. In this work, we present the first measurement of the average shower profile in traversed atmospheric depth at the Pierre Auger Observatory. The shapes of profiles are well reproduced by the Gaisser-Hillas parametrization within the range studied, for E>10 17.8 eV .A detailed analysis of the systematic uncertainties is performed using ten years of data and a full detector simulation. The average shape is quantified using two variables related to the width and asymmetry of the profile, and …
Generare la memoria. Padri e figli nel Mediterraneo greco
2011
Il rapporto padri-figlia nel mondo greco attraverso alcune testimonianze letterarie basilari, da Omero ad Esiodo a Platone, con particolare attenzione al rapporto privilegiato tra logos, memoria e identita'.
Testing the nature of the Λ(1520)-resonance in proton-induced production
2006
The $\Lambda(1520)$ resonance has been recently studied in a unitarized coupled channel formalism with $\pi\Sigma(1385)$, $K\Xi(1530)$, $\bar{K}N$ and $\pi\Sigma$ as constituents blocks. We provide a theoretical study of the predictions of this model in physical observables of the $pp\to pK^+K^-p$ and $pp\to pK^+\pi^0\pi^0\Lambda$ reactions. In particular, we show that the ratio between the $\pi^0\pi^0\Lambda$ and $K^-p$ mass distributions can provide valuable information on the ratio of the couplings of the $\Lambda(1520)$ resonance to $\pi\Sigma(1385)$ and $\bar{K}N$ that the theory predicts. Calculations are done for energies which are accessible in an experimental facility like COSY at …
Il simbolismo della spirale nella panificazione cerimoniale
2008
Il saggio analizza, attraverso un'ampia ricerca transculturale, la ricorrenza del simbolismo della spirale in rapporto ai temi della maternità e della commemorazione dei defunti al fine di evidenziare eventuali comuni contenuti semantici, e non rapporti meramente formali, tra i diversi contesti in cui appaiono simboli spiraliformi.