Search results for "ADULT"
showing 10 items of 17453 documents
IFI16 expression is related to selected transcription factors during B-cell differentiation
2015
The interferon-inducible DNA sensor IFI16 is involved in the modulation of cellular survival, proliferation, and differentiation. In the hematopoietic system, IFI16 is consistently expressed in the CD34+ stem cells and in peripheral blood lymphocytes; however, little is known regarding its regulation during maturation of B- and T-cells. We explored the role of IFI16 in normal B-cell subsets by analysing its expression and relationship with the major transcription factors involved in germinal center (GC) development and plasma-cell (PC) maturation.IFI16mRNA was differentially expressed in B-cell subsets with significant decrease inIFI16mRNA in GC and PCs with respect to naïve and memory subs…
B lymphocyte intestinal homing in inflammatory bowel disease.
2011
Abstract Background Inflammatory bowel disease (IBD) is thought to be due to an abnormal interaction between the host immune system and commensal microflora. Within the intestinal immune system, B cells produce physiologically natural antibodies but pathologically atypical anti-neutrophil antibodies (xANCAs) are frequently observed in patients with IBD. The objective is to investigate the localisation of immunoglobulin-producing cells (IPCs) in samples of inflamed intestinal tissue taken from patients with IBD, and their possible relationship with clinical features. Methods The IPCs in small intestinal, colonic and rectal biopsy specimens of patients with IBD were analysed by means of immun…
Preguntas de comprensión audiovisual sobreimpresas: propuesta para el aprendizaje de segundas lenguas
2018
Las actividades de comprensión audiovisual son complejas, especialmente en una segunda lengua. Por un lado, existe un conflicto de atención visual entre ver un vídeo y realizar una tarea escrita simultáneamente. Por otro lado, prestar atención a la imagen, al audio, y a la actividad al mismo tiempo puede saturar la memoria de trabajo. En este artículo se describe una propuesta innovadora que puede ayudar a limitar esta complejidad en las áreas de la enseñanza y la evaluación de segundas lenguas: el uso de preguntas de comprensión audiovisual integradas en la imagen del vídeo en forma de subtítulos y sincronizadas con los fragmentos relevantes. La propuesta es el resultado de una investigaci…
Emerging Constructions in the L2 Italian Spoken by Low Literate Migrants
2019
The emergence of autonomous interlanguage constructions is widely recognised in the literature on L2 Italian. These constructions involve the overgeneralisation of functional forms learners are in the process of acquiring, e.g., siamo in siamo mangiare &lsquo
Modulation of the Endocannabinoids N-Arachidonoylethanolamine (AEA) and 2-Arachidonoylglycerol (2-AG) on Executive Functions in Human.
2013
Animal studies point to an implication of the endocannabinoid system on executive functions. In humans, several studies have suggested an association between acute or chronic use of exogenous cannabinoids (Δ9-tetrahydrocannabinol) and executive impairments. However, to date, no published reports establish the relationship between endocannabinoids, as biomarkers of the cannabinoid neurotransmission system, and executive functioning in humans. The aim of the present study was to explore the association between circulating levels of plasma endocannabinoids N-arachidonoylethanolamine (AEA) and 2-Arachidonoylglycerol (2-AG) and executive functions (decision making, response inhibition and cognit…
Might as well jump: Sound affects muscle activation in skateboarding
2014
The aim of the study is to reveal the role of sound in action anticipation and performance, and to test whether the level of precision in action planning and execution is related to the level of sensorimotor skills and experience that listeners possess about a specific action. Individuals ranging from 18 to 75 years of age - some of them without any skills in skateboarding and others experts in this sport - were compared in their ability to anticipate and simulate a skateboarding jump by listening to the sound it produces. Only skaters were able to modulate the forces underfoot and to apply muscle synergies that closely resembled the ones that a skater would use if actually jumping on a ska…
Estrategias de afrontamiento en adultos mayores en función de variables sociodemográficas (Coping strategies in older adults as a function of sociode…
2015
Coping strategies are used to adapt to the changes that occur during aging. This study investigated 275 older adults who attended a senior citizen’s centre. They provided sociodemographic data and answered the Stress Coping Questionnaire (SCQ) in a semistructured interview. The aim was to analyse the use of coping strategies based in several sociodemographic variables, using correlations, t tests, and ANOVAs. The results showed a positive and significant association between age and religion, and differences were found in gender, marital status, educational attainment, and income level. In conclusion, as age increases, religion is most commonly used coping strategy; women make greater use of…
Relationship between sleep quality and postural balance in community-dwelling older persons: A cross-sectional study
2019
Objetivo Determinar la relación entre la calidad del sueño y el equilibrio postural en las personas mayores que viven en la comunidad. Métodos Se aplicó un estudio analítico y transversal. Se reclutaron 53 sujetos que cumplían los criterios de selección. Se aplicó el índice de calidad del sueño de Pittsburgh (PSQI) y se realizó una prueba de equilibrio estático a través de una posturografía computarizada para evaluar el equilibrio postural. Resultados Cincuenta y tres sujetos entre 60 y 80 años (M = 70,13; desviación estándar: 6,06) fueron evaluados; 69,8% correspondían a mujeres y 30,2% a hombres. La prueba de correlación encontró una relación estadísticamente significativa y positiva, per…
Nursing competence in municipal in-patient acute care in Norway: a cross-sectional study
2020
Abstract Background The primary health care services are becoming increasingly complex, which presents challenges for the municipal nursing services. In Norway, municipal in-patient acute care (MipAC) has been introduced in all municipalities, and the competence at the services has been questioned. Few studies have examined the nursing services in the units. This study aims to get an overview of the nursing competence in those units across geographical regions, and different groups of organisation and localisation. Methods A cross-sectional study was conducted, and an ad hoc questionnaire was distributed to first-line leaders in all the MipAC units in Norway. Data were collected in the peri…
Comparison of degrees of maturity of rabbit lines selected for different traits
2015
[EN] The aim of this work was to study whether commercial nucleus lines of rabbits selected for different traits, and experimental lines having commercial purposes, have the same degree of maturity when compared at the same slaughter age. The study was carried out with 17897 rabbits from Universitat Politècnica de València. Rabbits came from the maternal lines A (3902 rabbits; 44th generation), V (4238 rabbits; 39th generation) and LP (6115 rabbits; 9th generation), selected for litter size at weaning; the paternal line R (2023 rabbits; 25th generation), selected for growth rate between 28 and 63 days of age; the maternal line OR (586 rabbits; 11th generation) selected for ovulation rate; a…