Search results for "AEM"

showing 10 items of 1006 documents

Bispectral index variations in patients with neurological deficits during awake carotid endarterectomy

2010

The bispectral index (BIS) is derived from the EEG and therefore may be useful to diagnose intraoperative cerebral ischaemia. This study was undertaken to investigate BIS changes in awake patients with and without neurological deficits during carotid endarterectomy under regional anaesthesia.Seventy consecutive carotid endarterectomies under regional anaesthesia were divided into two surgical groups: patients with and patients without neurological deficits. Patients' neurological status was evaluated and neurological deficits were compared with BIS values. Measurements were made at different surgical stages: baseline, after sedation, at the beginning of surgery, at preclamping, at the 3 min…

Malemedicine.medical_treatmentCarotid endarterectomyElectroencephalographyBrain IschemiaBrain ischemiamedicineHumansAnesthesiaIn patientProspective StudiesProspective cohort studyAgedEndarterectomyEndarterectomy Carotidmedicine.diagnostic_testbusiness.industryElectroencephalographyMiddle Agedmedicine.diseaseTreatment OutcomeAnesthesiology and Pain MedicineBispectral indexAnesthesiaFemaleCerebral ischaemiaNervous System DiseasesbusinessEuropean Journal of Anaesthesiology
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The oxidative cost of reproduction depends on early development oxidative stress and sex in a bird species

2016

In the early 2000s, a new component of the cost of reproduction was proposed: oxidative stress. Since then the oxidative cost of reproduction hypothesis has, however, received mixed support. Different arguments have been provided to explain this. Among them, the lack of a life-history perspective on most experimental tests was suggested. We manipulated the levels of a key intracellular antioxidant (glutathione) in captive zebra finches (Taeniopygia guttata) during a short period of early life and subsequently tested the oxidative cost of reproduction. Birds were allowed to mate freely in an outdoor aviary for several months. We repeatedly enlarged or reduced their broods to increase or redu…

Malepredictive adaptive response0106 biological sciences0301 basic medicineAntioxidantmedicine.medical_treatmentmedia_common.quotation_subjectZoologymedicine.disease_causephenotypic plasticity010603 evolutionary biology01 natural sciencesAntioxidantsGeneral Biochemistry Genetics and Molecular BiologySongbirdsearly development conditions03 medical and health scienceschemistry.chemical_compoundPredictive adaptive responsemedicineAnimals[ SDV.BDD ] Life Sciences [q-bio]/Development Biologyenvironmental matching[SDV.BDD]Life Sciences [q-bio]/Development BiologyResearch ArticlesGeneral Environmental Sciencemedia_commonPhenotypic plasticityGeneral Immunology and MicrobiologybiologyEcologyReproduction[SDV.BID.EVO]Life Sciences [q-bio]/Biodiversity/Populations and Evolution [q-bio.PE]life-history trade-offsGeneral MedicineGlutathionebiology.organism_classificationHaemolysisGlutathioneOxidative Stress[ SDV.BID.EVO ] Life Sciences [q-bio]/Biodiversity/Populations and Evolution [q-bio.PE]030104 developmental biologychemistryFemaleReproductionGeneral Agricultural and Biological SciencesTaeniopygiaOxidative stressProceedings of the Royal Society B: Biological Sciences
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Variability in protein binding of teicoplanin and achievement of therapeutic drug monitoring targets in critically ill patients: Lessons from the DAL…

2014

The aims of this study were to describe the variability in protein binding of teicoplanin in critically ill patients as well as the number of patients achieving therapeutic target concentrations. This report is part of the multinational pharmacokinetic DALI Study. Patients were sampled on a single day, with blood samples taken both at the midpoint and the end of the dosing interval. Total and unbound teicoplanin concentrations were assayed using validated chromatographic methods. The lower therapeutic range of teicoplanin was defined as total trough concentrations from 10 to 20 mg/L and the higher range as 10-30 mg/L. Thirteen critically ill patients were available for analysis. The followi…

Malevalidityvalidation proceInternational CooperationSettore MED/41 - Anestesiologiadrug protein bindingGastroenterologylaw.inventionPlasmaStaphylococcus infectionCritically ill patientsInterquartile rangelaw[SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseasesAntibioticsantibiotic therapyPharmacology (medical)Pharmacology & PharmacyAntibiotics; Critically ill patients; Glycopeptides; Hypoalbuminaemia; ICU; Pharmacokinetics; Adult; Aged; Anti-Bacterial Agents; Chromatography; Critical Illness; Female; Humans; International Cooperation; Male; Middle Aged; Plasma; Protein Binding; Teicoplanin; Young Adult; Drug Monitoring; Microbiology (medical); Infectious Diseases; Pharmacology (medical)Antibiotics; Critically ill patients; Glycopeptides; Hypoalbuminaemia; ICU; Pharmacokinetics; Adult; Aged; Anti-Bacterial Agents; Chromatography; Critical Illness; Female; Humans; International Cooperation; Male; Middle Aged; Plasma; Protein Binding; Teicoplanin; Young Adult; Drug Monitoringclinical articleChromatographymedicine.diagnostic_testdrug dose regimencritical illneTeicoplaninHypoalbuminaemiaMedicine (all)articleGlycopeptidesclinical trialGeneral MedicineMiddle Agedtrough time concentrationdrug protein binding variabilityIntensive care unitGlycopeptides Antibiotics Critically ill patients Pharmacokinetics Hypoalbuminaemia ICU3. Good healthAnti-Bacterial Agentsantiinfective agentdrug distributionInfectious Diseases[SDV.MP]Life Sciences [q-bio]/Microbiology and Parasitologypriority journalmulticenter study (topic)Vancomycinblood samplingFemaleCritically ill patientDrug MonitoringHumanmedicine.drugProtein BindingMicrobiology (medical)Adultmedicine.medical_specialtyhigh performance liquid chromatographyarea under the curveCritical Illnessultraviolet spectroscopymid dose concentrationchemistryGlycopeptideMicrobiologyteicoplanin adultenterococcal infectionyoung adult Adultdrug clearanceYoung AdultTherapeutic indexPharmacokineticsInternal medicineAnti-Bacterial AgentmedicineHumanssteady statePharmacokineticsDosingAgedbusiness.industrydrug half lifeAntibioticrecommended drug doseAntibiotics; Critically ill patients; Glycopeptides; Hypoalbuminaemia; ICU; Pharmacokinetics; Adult; Aged; Anti-Bacterial Agents; Chromatography; Critical Illness; Female; Humans; International Cooperation; Male; Middle Aged; Plasma; Protein Binding; Teicoplanin; Young Adult; Drug Monitoring; Microbiology (medical); Infectious Diseases; Pharmacology (medical); Medicine (all)calibrationSurgerymulticenter studyTherapeutic drug monitoringdrug blood levelICU[SDV.SP.PHARMA]Life Sciences [q-bio]/Pharmaceutical sciences/Pharmacologyfree plasma drug concentrationTeicoplaninbusinessmetabolism
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MATHEMATISATION: SOCIAL PROCESS & DIDACTIC PRINCIPLE

2017

The 69th CIEAEM conference was held from 15th to 19th July 2017 at Freie Universität Berlin, Germany. It successfully involved 100 participants from 20 countries all over the world. CIEAEM 69 was dedicated to Professor Christine Keitel, president of CIEAEM from 1997 to 2003, who tragically passed away one year before the conference. The programme of the conference started with a panel that revisited “Mathematics (Education) and Common Sense”, the theme of the 47th CIEAEM conference, which was held in Berlin in July 1995 and which was hosted by Christine. At the conference, researchers, teachers, educators, and students met to discuss, in a collaborative and inspiring environment, the most p…

Mathematics Education CIEAEMSettore MAT/04 - Matematiche Complementari
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MATHEMATIQUES ET VIVRE ENSEMBLE": POURQUOI, QUOI, COMMENT? - "MATHEMATICS AND LIVING TOGETHER": WHY, HOW, WHAT?

2019

The 70th CIEAEM conference was held from 15th to 19th July 2018 at Université de Mostaganem - Fondation Djanatu Al Arif, Mostaganem (Algerie). It successfully involved several participants from many countries all over the world. At the conference, researchers, teachers, educators, and students discussed, with a collaborative and inspiring attitude, different significant problems, obstacles and resources related to mathematics education and the important theme of the conference “What is living together?”; they also presented their latest research findings in the several conference activities: plenary talks, working groups, workshops, and poster presentations (forum of ideas). As in previous …

Mathematics Didactic of Mathematics CIEAEMMatematica Didattica della Matematica CIEAEMSettore MAT/04 - Matematiche Complementari
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Temporal patterns in immune responses to a range of microbial insults (Tenebrio molitor).

2008

8 pages; International audience; Much work has elucidated the pathways and mechanisms involved in the production of insect immune effector systems. However, the temporal nature of these responses with respect to different immune insults is less well understood. This study investigated the magnitude and temporal variation in phenoloxidase and antimicrobial activity in the mealworm beetle Tenebrio molitor in response to a number of different synthetic and real immune elicitors. We found that antimicrobial activity in haemolymph increased rapidly during the first 48h after a challenge and was maintained at high levels for at least 14 days. There was no difference in the magnitude of responses …

MealwormProphenoloxidaseTime FactorsPhysiology[ SDV.BA.ZI ] Life Sciences [q-bio]/Animal biology/Invertebrate ZoologyAntimicrobial peptidesBacillus subtilisMicrobiologyImmune systemDownregulation and upregulationHemolymphHemolymphEscherichia coliAnimals[ SDV.IMM ] Life Sciences [q-bio]/ImmunologyTenebrioEnzyme PrecursorsbiologyMonophenol MonooxygenaseZone of inhibitionLong-lasting immunityProphenoloxidaseAntimicrobialbiology.organism_classificationHaemolymphInsect ScienceHost-Pathogen InteractionsInsect immunityPhenoloxidaseAntimicrobial peptidesCatechol OxidaseAntimicrobial Cationic PeptidesBacillus subtilis
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May Measurement Month 2018: an analysis of blood pressure screening results from Italy

2020

Abstract Cardiovascular (CV) diseases are burdened by high mortality and morbidity, being responsible for half of the deaths in Europe. Although hypertension is recognized as the most important CV risk factor, hypertension awareness and blood pressure (BP) control are still unsatisfactory. In 2017, 30.6% of a >10 000 individual sample who took part in the May Measurement Month (MMM) campaign in Italy was found to have high BP. To raise awareness on the hypertension issue and to report BP data on a nation-wide scale in Italy. In the frame of the MMM campaign, an opportunistic cross-sectional survey of volunteers aged ≥18 was carried out in May 2018. Blood pressure measurement, the def…

Mean arterial pressure030204 cardiovascular system & hematology03 medical and health sciences0302 clinical medicineDiabetes mellitusHealth careControlmedicineAcademicSubjects/MED00200030212 general & internal medicineRisk factor1102 Cardiorespiratory Medicine and HaematologyNational healthbusiness.industryHigh mortalityBlood pressure Control Hypertension Screening TreatmentArticlesmedicine.diseasehypertension; blood pressure; screening; treatment; controlTreatmentBlood pressureCardiovascular System & HematologyHypertensionBlood pressureScreeningCardiology and Cardiovascular MedicinebusinessBody mass indexBlood pressure; Control; Hypertension; Screening; TreatmentDemography
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May Measurement Month 2019: an analysis of blood pressure screening results from Italy.

2021

Abstract Cardiovascular (CV) diseases are burdened by high mortality and morbidity, being responsible for half of the deaths in Europe. Although hypertension is recognized as the most important CV risk factor, hypertension awareness, and blood pressure (BP) control are still unsatisfactory. In 2017 and 2018, respectively >10 000 and >5000 individuals took part in the May Measurement Month (MMM) campaign in Italy, of whom 30.6% and 26.3% were found to have high BP, respectively. To raise public awareness on the importance of hypertension and to collect BP data on a nation-wide scale in Italy. In the frame of the MMM campaign, an opportunistic cross-sectional survey of volunteer…

Mean arterial pressure030204 cardiovascular system & hematology03 medical and health sciencesHealth personnel0302 clinical medicineHealth campaignDiabetes mellitusControlMedicineBlood pressure Control Screening TreatmentAcademicSubjects/MED00200030212 general & internal medicineMyocardial infarctionRisk factorTreatment.1102 Cardiorespiratory Medicine and HaematologySettore MED/14 - Nefrologiabusiness.industryArticlesmedicine.diseaseSettore MED/11 - Malattie Dell'Apparato CardiovascolareTreatmentBlood pressureCardiovascular System & HematologyHypertensionBlood pressureScreeningCardiology and Cardiovascular MedicinebusinessBody mass indexBlood pressure; Control; Hypertension; Screening; TreatmentDemographyEuropean heart journal supplements : journal of the European Society of Cardiology
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Does the immune answer to Bacillus thuringiensis infection is the same in larvae, females and males of Rhynchophorus ferrugineus?

2021

Bacillus thuringiensis (Bt) è considerato un potenziale batterio entomopatogeno per la lotta al Rhynchophorus ferrugineus, coleottero da quarantena infestante le palme. In questo lavoro si considerano gli effetti dell’infezione di Bt in larve, maschi e femmine del punteruolo rosso. La patogenicità è stata valutata stimando la LD50 (Lethal Median Dose) e la LT50 (Lethal Median Time), il numero totale di emociti ed il tipo di emociti (Differential Haemocytes counts) ed inoltre l’espressione delle proteine Heat Shock Protein 70 (HSP70) negli emociti e nel cerebro. La mortalità di entrambi i sessi e delle larve aumentava all’aumentare della dose e del tempo di esposizione. Tuttavia le larve han…

Median lethal dose median lethal time stress answer haemocytes brain HSP70.Settore AGR/11 - Entomologia Generale E ApplicataSettore BIO/05 - Zoologiadose letale mediana tempo letale mediano risposta allo stress emociti cerebro HSP70
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Comparative effects of carrier proteins on vaccine-induced immune response

2011

The efficacy of vaccines against major encapsulated bacterial pathogens -Neisseria meningitidis, Streptococcus pneumoniae, and Haemophilus influenzae type b (Hib) - has been significantly enhanced by conjugating the respective polysaccharides with different carrier proteins: diphtheria toxoid; non-toxic cross-reactive material of diphtheria toxin(197), tetanus toxoid, N. meningitidis outer membrane protein, and non-typeable H. influenzae-derived protein D. Hib, meningococcal, and pneumococcal conjugate vaccines have shown good safety and immunogenicity profiles regardless of the carrier protein used, although data are conflicting as to which carrier protein is the most immunogenic. Coadmini…

Meningococcal Vaccineschemical and pharmacologic phenomenamedicine.disease_causecomplex mixturesMicrobiologyPneumococcal VaccinesImmune systemAdjuvants ImmunologicConjugate vaccineStreptococcus pneumoniaemedicineHumansHaemophilus VaccinesDiphtheria toxinVaccines ConjugateGeneral VeterinaryGeneral Immunology and MicrobiologyChemistryNeisseria meningitidisImmunogenicityPolysaccharides BacterialPublic Health Environmental and Occupational HealthToxoidVaccine efficacyVirologyInfectious DiseasesMolecular MedicineCarrier ProteinsVaccine
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