Search results for "AGN"
showing 10 items of 28126 documents
Biodegradable Metal-Organic Framework-Based Microrobots (MOFBOTs).
2020
Microrobots and metal–organic frameworks (MOFs) have been identified as promising carriers for drug delivery applications. While clinical applications of microrobots are limited by their low drug loading efficiencies and the poor degradability of the materials used for their fabrication, MOFs lack motility and targeted drug delivery capabilities. The combination of these two fields marks the beginning of a new era; MOF‐based small‐scale robots (MOFBOTs) for biomedical applications. Yet, biodegradability is a major hurdle in the field of micro‐ and nanoswimmers including small‐scale robots. Here, a highly integrated MOFBOT that is able to realize magnetic locomotion, drug delivery, and selec…
Phosphorus limitation enhances parasite impact: feedback effects at the population level
2014
Background Nutrient deficiency affects the growth and population dynamics of consumers. Endoparasites can be seen as consumers that drain carbon (C) or energy from their host while simultaneously competing for limiting resources such as phosphorus (P). Depending on the relative demands of the host and the parasite for the limiting nutrient, intensified resource competition under nutrient limitation can either reduce the parasite’s effect on the host or further reduce the fitness of the nutrient-limited host. So far, knowledge of how nutrient limitation affects parasite performance at the host population level and how this affects the host populations is limited. Results We followed the popu…
Les établissements ruraux palissadés hallstattiens en Champagne
2010
Die im östlichen Teil des Pariser Beckens bekannten Siedlungen mit Palisadenanlagen der Hallstattzeit werden seit ein paar Jahren häufiger in der Kreidelandschaft der trockenen Champagne entdeckt. Der aktuelle Zuwachs des regionalen Datenbestands gibt Anlaß, diese Art von Siedlungen nun näher zu erforschen und Arbeitshypothesen zu ihrer Chronologie, Funktion und sozialer Stellung in der damaligen Zeit aufzustellen. Ihre maximale zeitliche Ausdehnung er - streckt sich anscheinend vom Ende der späten Bronzezeit bis zum Ende der Hallstattzeit, aber es existieren noch viele Fragen über den genauen Rhythmus der Besiedlung und der Bewirtschaftung der landwirtschaftlichen Flächen. Wei - ter hin be…
De l'honneur et des épices : les magistrats de la Chambre des comptes de Bretagne (XVIe-XVIIe siècles)
2016
International audience; À travers l’exemple de la Chambre des comptes de Bretagne des années 1540 à la fin du règne de Louis XIV et surtout de l’étude de son personnel, cet ouvrage contribue à la connaissance des chambres des comptes et dégage quelques ressorts de la « société d’offices » qui s’est mise en place en France à partir du XVIe siècle. Ces chambres ont attiré tout au long de l’époque moderne une part des élites du royaume, en quête d’honneur et d’épices, qui voulaient bénéficier de privilèges dont principalement celui de l’anoblissement graduel.
Obesity and survival in operable breast cancer patients treated with adjuvant anthracyclines and taxanes according to pathological subtypes: a pooled…
2013
Obesity is an unfavorable prognostic factor in breast cancer (BC) patients regardless of menopausal status and treatment received. However, the association between obesity and survival outcome by pathological subtype requires further clarification. METHODS: We performed a retrospective analysis including 5,683 operable BC patients enrolled in four randomized clinical trials (GEICAM/9906, GEICAM/9805, GEICAM/2003-02, and BCIRG 001) evaluating anthracyclines and taxanes as adjuvant treatments. Our primary aim was to assess the prognostic effect of body mass index (BMI) on disease recurrence, breast cancer mortality (BCM), and overall mortality (OM). A secondary aim was to detect differences o…
Experimental study of MMI structures in a switchable continuous-wave thulium-doped all-fiber laser
2022
Switchable multi-wavelength laser emission from a thulium-doped all-fiber laser is reported by implementing a tapered and a non-tapered multi-modal interference (MMI) filters. The MMI structure relies on a coreless optical fiber spliced in between two single-mode optical fibers. For the non-tapered case, a minimum insertion loss of 12.60 dB is achieved around the 2-μm region, from which stable generation of commutable dual-wavelength emission at 1986.34 nm and 2017.38 nm is obtained. On the other hand, the tapered MMI structure performs a minimum insertion loss of 8.74 dB at the 2-μm region, allowing a stable triple-wavelength emission at 1995.4 nm, 2013.3 nm, and 2038.3 nm. In addition, co…
Narrowband Monolithic Perovskite-Perovskite Tandem Photodetectors
2022
Narrowband photodetectors (PDs) are sought after for many applications requiring selective spectral response. The most common systems combine optical bandpass filters with broadband photodiodes. This work reports a method to obtain a narrowband response in a perovskite PD by the monolithic integration of a perovskite photoconductor and a perovskite photodiode. The spectral response of the tandem PD is determined by the bandgap energy difference of the two perovskites, and exhibits a full width at half maximum below 85 nm, an external quantum efficiency up to 68% and a high specific detectivity of ≈1012 Jones in reverse bias, enabling the device to detect weak light signals. The absorption p…
Utilidad de la resonancia magnética en la predicción de la continencia urinaria tras prostatectomía radical endoscópica extraperitoneal
2015
Introducción: El cáncer de próstata es un problema de salud importante. Es la localización más frecuente de cáncer en el varón. Afortunadamente la tasa de curación es alta, con una tasa de supervivencia del 87% al año y del 65% a los 5 años. La mayor parte de los tumores que se diagnostican se encuentran es estadios órgano confinados. En la actualidad la mejor técnica para el estudio de extensión y para la planificación de una posible cirugía es la resonancia magnética. Si bien, la prostatectomía radical se define como el patrón de oro como terapia para el cáncer de próstata, no está exenta de complicaciones. La incontinencia urinaria es la morbilidad a largo plazo que más mina la calidad d…
Kantojen korjuun vaikutukset änkyrimatojen (Enchytraeidae) yksilömäärään ja kasvillisuuteen
2007
Patrimonialiser la nuit ? Une appropriation de la transition énergétique dans les territoires touristiques
2015
International audience