Search results for "AGS"

Technology, Innovation and Knowledge

2016

The relevance of ideas is at the core of the IB field and has been captured in concepts like technology, innovation and knowledge. While these concepts have evolved over the last decades, the point that the ideas and the international connectivity are central for IB remains genuine. This paper is an attempt to take stock of the evolution of the concepts technology, innovation and knowledge in IB literature along the past five decades with a particular focus on the role of the Columbia Journal of World Business (CJWB) and the Journal of World Business (JWB) in this evolution. Likewise, our objective is to offer a research agenda for the coming decade. We proceed in two steps. First, we scrut…

Brief an Garlieb H. Merkel

1799

Ms. 930a, Nr. 18, Bl. 45r-46v Justus C. Loder. Brief an GarliebH. Merkel, Jena, den 19. Jul[i] 1799 Autora rokraksts / Autograph, vācuval. / Deutsch [2] lpp. / S. Attēlu numuri / Bildnummern: 930a-018-1, 930a-018-2 Der kurze Brief, der wahrscheinlich von Justus C. Loder stammt, hat vor allem zum Ziel, scheinbar erneut, Merkel einzuladen und die Verbundenheit mit ihm zum Ausdruck zu bringen.Loder, der zu diesem Zeitpunkt Professor für Medizin in Jena war, stammte aus Riga, woraus sich ein besonderes Verhältnis zu Livland und zum Adressaten entstammt haben könnte. Es ist naheliegend, dass Merkel während seines kurzen, aber nicht zu Ende geführten Medizinstudiums, das er in Leipzig begann und …

Tetrazine Linkers as Plug-and-Play Tags for General Framework Functionalization and C60 Conjugation

2022

The value of covalent post-synthetic modification in expanding the chemistry and pore versatility of reticular solids is well documented. Here we use mesoporous crystals of UiO-68-TZDC to demonstrate the value of tetrazine connectors for all-purpose inverse electron-demand Diels-Alder ligation chemistry. Our results suggest a positive effect of tetrazine reticulation over its reactivity for quantitative one-step functionalization with a broad scope of alkene or alkyne dienophiles into pyridazine and dihydropyridazine frameworks. This permits generating multiple pore environments with diverse chemical functionalities and the expected accessible porosities, that is also extended to the synthe…

Mitochondrial genome sequence and gene order of Sipunculus nudus give additional support for an inclusion of Sipuncula into Annelida.

2010

Abstract Background Mitochondrial genomes are a valuable source of data for analysing phylogenetic relationships. Besides sequence information, mitochondrial gene order may add phylogenetically useful information, too. Sipuncula are unsegmented marine worms, traditionally placed in their own phylum. Recent molecular and morphological findings suggest a close affinity to the segmented Annelida. Results The first complete mitochondrial genome of a member of Sipuncula, Sipunculus nudus, is presented. All 37 genes characteristic for metazoan mtDNA were detected and are encoded on the same strand. The mitochondrial gene order (protein-coding and ribosomal RNA genes) resembles that of annelids, b…

Electrostatic Tuning of the Ligand Binding Mechanism by Glu27 in Nitrophorin 7

2018

AbstractNitrophorins (NP) 1–7 are NO-carrying heme proteins found in the saliva of the blood-sucking insect Rhodnius prolixus. The isoform NP7 displays peculiar properties, such as an abnormally high isoelectric point, the ability to bind negatively charged membranes, and a strong pH sensitivity of NO affinity. A unique trait of NP7 is the presence of Glu in position 27, which is occupied by Val in other NPs. Glu27 appears to be important for tuning the heme properties, but its influence on the pH-dependent NO release mechanism, which is assisted by a conformational change in the AB loop, remains unexplored. Here, in order to gain insight into the functional role of Glu27, we examine the ef…

Active Moss biomonitoring of mercury in the mine-polluted area of Mt. Amiata (Central Italy)

2015

In the winter 2013, mercury concentrations in air from the mine-polluted area of Mt. Amiata (1738 m a.s.l.), in southern Tuscany (Central Italy), were measured by active moss biomonitoring. This area is part of the geologic anomaly of Hg in the Mediterranean basin, which contains about 65 % of the world’s cinnabar (HgS). Mt. Amiata covers some 400 km2 and is drained by several rivers. Esploitation activity at Abbadia S. Salvatore, in the SE sector of the mountain, sprang up during the 19th century as one of the largest mercury mining and smelting plants in Europe, after those of Almaden Spain. In this area, Sphagnum moss bags were exposed for about two months, from October to December 2013.…

Villancicos que se han de cantar en la Real Capilla de las Señoras de la Encarnacion, la noche de los Santos Reyes de este año de M.DCC.XI

1711

Sig. A6 Escut reial orlat flanquejat per ornaments florals a la port. - Fris Port. orlada. - Text a dues col. separades per banda. - Reclams

Kalmbergin kartasto R VIII : List 11

1855

Respiratory proteins in Sipunculus nudus--implications for phylogeny and evolution of the hemerythrin family.

2009

Three major classes of respiratory proteins are known, hemoglobin, molluscan and arthropod hemocyanin, and hemerythrin (Hr). Similar to hemoglobin, respiratory Hr is packed into erythrocytes floating in the coelomic fluid and is only known from sipunculids, brachiopods, and priapulids. Owing to this scattered distribution, the presence of Hr is generally assumed to be the plesiomorphic condition without phylogenetic importance. By sequencing 2000 Expressed Sequence Tags (ESTs) from Sipunculus nudus, we found 75 Hr-coding ESTs assembled to 20 cDNA contigs classified as four distinct Hr isoforms: three polymeric Hrs (subunit A, A', and B) and the monomeric myo-hemerythrin (myoHr). Phylogeneti…

How social network sites and other online intermediaries increase exposure to news

2020

Research has prominently assumed that social media and web portals that aggregate news restrict the diversity of content that users are exposed to by tailoring news diets toward the users’ preferences. In our empirical test of this argument, we apply a random-effects within–between model to two large representative datasets of individual web browsing histories. This approach allows us to better encapsulate the effects of social media and other intermediaries on news exposure. We find strong evidence that intermediaries foster more varied online news diets. The results call into question fears about the vanishing potential for incidental news exposure in digital media environments.