Search results for "AHA"
showing 10 items of 1702 documents
The overlapping burden of the three leading causes of disability and death in sub-Saharan African children
2022
Publisher Copyright: © 2022, The Author(s). Despite substantial declines since 2000, lower respiratory infections (LRIs), diarrhoeal diseases, and malaria remain among the leading causes of nonfatal and fatal disease burden for children under 5 years of age (under 5), primarily in sub-Saharan Africa (SSA). The spatial burden of each of these diseases has been estimated subnationally across SSA, yet no prior analyses have examined the pattern of their combined burden. Here we synthesise subnational estimates of the burden of LRIs, diarrhoea, and malaria in children under-5 from 2000 to 2017 for 43 sub-Saharan countries. Some units faced a relatively equal burden from each of the three diseas…
Global, regional, and national burden of mortality associated with non-optimal ambient temperatures from 2000 to 2019: a three-stage modelling study
2021
Background: Exposure to cold or hot temperatures is associated with premature deaths. We aimed to evaluate the global, regional, and national mortality burden associated with non-optimal ambient temperatures. Methods: In this modelling study, we collected time-series data on mortality and ambient temperatures from 750 locations in 43 countries and five meta-predictors at a grid size of 0·5° × 0·5° across the globe. A three-stage analysis strategy was used. First, the temperature–mortality association was fitted for each location by use of a time-series regression. Second, a multivariate meta-regression model was built between location-specific estimates and meta-predictors. Finally, the gri…
Unvolvement of calcium signaling and MAP kinases in lipid taste perception
2013
In this work, we demonstrate that stromal interaction molecule 1 (STIM1), a sensor of Ca2+ depletion in the endoplasmic reticulum, mediates fatty acid–induced Ca2+ signaling in the mouse tongue and fat preference. We showed that linoleic acid (LA) induced the production of arachidonic acid (AA) and lysophosphatidylcholine (Lyso-PC) by activating multiple phospholipase A2 isoforms via CD36. This activation triggered Ca2+ influx in lingual CD36-positive taste bud cells (TBCs) purified from mouse CVP. LA also induced the production of Ca2+ influx factor (CIF). STIM1 was found to regulate LA-induced CIF production and the opening of store-operated Ca2+ (SOC) channels. Furthermore, CD36-positive…
Jawaharlal Nehrun näkemyksiä britti-imperialismista Intiassa ennen itsenäistymistä 1947
1999
Zvaigžņotā Debess: 2004/05, Ziema
2004
Contents: Ņ.Ozoliņa. Earthquakes in Latvia ; I.Daube. Space Craft “Ranger-7” ; M. Gailis. Moon Investigation in Riga ; J.Tambergs. Problems of Dialogue between Quantum Mechanics and Theology (concluded) ; Z Alksne, A.Alksnis. Ultra-Cool Dwarf Pair Weighed ; A.Balklavs. Successful Hunt of Protostars ; A.Balklavs. Silhouette of a Black Hole ; A.Balklavs. A Distant Giant Quasar ; A.Balklavs. Cosmic Objects in Captivating Photos – 3 ; J.Freimanis. Extragalactic Planetary Nebulae ; J.Jaunbergs. Cassini Enters the Saturnian System ; D.Krieviņš. Space Launchers of Early XXI Century. The Commonwealth of Independent States (CIS) ; J.Bārzdiņš. Professor Rusins-Martins Freivalds on the Path of Science…
Combined impacts of the Allee effect, delay and stochasticity: Persistence analysis
2020
Abstract We study a combined influence of the Allee effect, delay and stochasticity on the base of the phenomenological Hassell mathematical model of population dynamics. This bistable dynamical model possesses a wide variety of regimes, both regular and chaotic. In the persistence zone, these regimes coexist with the trivial equilibrium that corresponds to the extinction of the population. It is shown that borders of the persistence zone are defined by the crisis and saddle-node bifurcation points. Noise-induced transitions from the persistence to the extinction are studied both numerically and analytically. Using numerical modeling, we have found that the persistence zone can decrease and…
Kotoutumiskoulutuksen opetussuunnitelman perusteet kuvaa tavoitettaan osallisuutta epämääräisesti ja kapeasti
2023
Kotoutumiskoulutuksen uudessa perusteasiakirjassa korostuu osallisuuden käsite. Se jää kuitenkin määrittelemättä: osallisuuteen viitataan sekä kapearajaisesti työmarkkinaosallisuutena että epäsuorasti niin, että käsitteen varsinainen merkitys jää avoimeksi. Tutkimuskirjallisuudessa osallisuus edellyttää laaja-alaista sosiaalis-yhteiskunnallista kuulumista ja yhdenvertaisuutta. nonPeerReviewed
Sähköinen arkistointi ja pitkäaikaissäilytys Suomessa valmisohjelmistolla
2012
Arkistointi on hävittämisen taidetta. Kun työkalut ovat hallussa, tietää lainalaisuudet ja käytettävät standardit, voi keskittyä tähän taitolajiin, mitä säilyttää ja mitä hävittää. Tässä työssäni tarkastelen sähköisen arkistoinnin ja pitkäaikaissäilytykset peruskäsitteet, merkittävimmät standardit ja ohjelmistot. Lisäksi avaan lainalaisuuksia ja koitan selvittää kuinka lainsäädäntö säätelee sähköistä arkistointia. Tutkin kuusi suomessa toteutettua julkishallinnon arkistointi ja/tai pitkäaikaissäilytysratkaisua. Julkishallinnon asiakirjanhallinta ja arkistointi on selkeää, sitä ohjaa lainsäädäntö ja Arkistolaitos. Muiden täytyy ymmärtää ensin syyt, joiden takia arkistoidaan tietoa, sekä kaua…
Education for all : the hazard within fragile states
2012
Currently, over a third of children not in school live in countries considered being as fragile. These countries, which are mainly located in sub-Saharan Africa, will not reach the objectives of Education For All for 2015. This thesis covers approaches across comparative education, political science and sociology of organizations. It explores empirically the condi¬tions of achievement of EFA within the contexts of fragility. Despite its ambiguities, the notion of fragile states was adopted in 2005 as an operational concept by most of aid agencies. Definitions of fragile state converge on a set of specific criteria (dysfunctional institutions, chronic socio-political instability, limited acc…
The effectiveness of aid on education in fragile states
2012
Universal primary education (UPE) is one of the main aims of Official Development Aid (ODA). In the last years, the issues of aid effectiveness were widely discussed in the literature. Little empirical evidence of its effectiveness exists, particularly for fragile states. In these countries, mainly in Sub-Saharan Africa, universal primary schooling will be off target for 2015, so invalidates the Millennium Development Goals. By means of a panel database, we attempt to measure the effects of official development assistance in education over a sample of 17 fragile states in Africa from 1999 to 2010. We use the most disaggregated and reliable data existing. On one hand, our results indicate th…