Search results for "ALCA"
showing 10 items of 405 documents
COL1A1 Sp1 polymorphism associates with bone density in early puberty.
2006
Optimal acquisition of bone mass in puberty is a key determinant of the lifetime risk of osteoporosis and has a strong genetic basis. We investigated the relationship between the COL1A1 Sp1 polymorphism and BMD in early puberty, and how the genotypes relate to bone size and geometry as well as bone turnover and material properties in 247 10- to 13-year-old girls. Bone properties were measured using DXA, pQCT, and ultrasound. Also, serum P1NP, OC, B-ALP, and TRACP 5b were assessed. Our results showed that girls with the TT genotype had significantly lower BMC and BMD of the total body, lumbar spine, and proximal femur, as well as BUA at the calcaneus, than those with the GT and GG genotype. …
Does hysterectomy with ovarian conservation affect bone metabolism and density?
2002
We evaluated whether hysterectomy with ovarian conservation (HYX) has an effect on bone metabolism and density in 176 healthy Caucasian postmenopausal women aged 48-59 years. Bone properties of the hip, spine, radius, tibia, and calcaneus were measured using different bone assessment modalities. In addition, bone turnover was assessed using serum bone-specific alkaline phosphatase (BAP), osteocalcin (OC), and tartrate-resistant acid phosphatase (TRAP) 5b as biomarkers. Our results showed that women having HYX had a significantly lower level of OC ( P = 0.017) and a marginally lower level of TRAP 5b ( P = 0.051) and higher bone mineral density (BMD) of the femoral neck ( P = 0.037) and lumba…
Long Term Leisure Time Physical Activity Has a Positive Effect on Bone Mass Gain in Girls
2009
The purpose of this 7-year prospective longitudinal study was to examine whether the level and consistency of leisure-time physical activity (LTPA) during adolescence affected the bone mineral content (BMC) and bone mineral density (BMD) attained at early adulthood. The study subjects were 202 Finnish girls who were 10 to 13 years of age at baseline. Bone area (BA), BMC, and BMD of the total body (TB), total femur (TF), and lumbar spine (L2–L4) were assessed by dual-energy X-ray absorptiometry (DXA). Scores of LTPA were obtained by questionnaire. Girls were divided into four groups: consistently low physical activity (GLL), consistently high (GHH), and changed from low to high (GLH) and fro…
La pierre et les hommes en Bourgogne. Archéologie et histoire d'une ressource en œuvre du Moyen Âge à l'Époque Moderne
2014
In order to go further limits inherent to subject disjunction, or those imposed by sources, periods or sites, this thesis emphasises a multidisciplinary and diachronic approach of stone supply on medieval and modern building sites. Thanks to the confrontation of buildings with different origins and functions, this work tries to dissect process of choices and stone supply network. It finally considers connection between people and a natural ressource.
Le Clos de Vougeot (Côte-d’Or) : nouvelles observations sur les matériaux de construction et la chronologie du bâti médiéval
2009
Mithilfe sehr unterschiedlicherMethoden hat es sich diese Arbeit vor allem zur Aufgabe gemacht, bestimmte Phasen der Baugeschichte des Clos de Vougeot zu verstehen, um die Organisation und die Entwicklungen eines Zisterzienserhofsin Hinsicht auf diesozialen und historischen Wandlungen besser zu verstehen. Diese Studie bot ebenfalls Gelegenheit, die geologischen Eigenschaften der im Clos de Vougeot eingebrachten Baumaterialien genauestens zu untersuchen und neue Erkenntnisse zum Bau dieser Gebäude zu gewinnen und zu präzisieren.
Apolar versus polar solvents: a comparison of the strength of some organic acids against different bases in toluene and in water
2010
The constants of ion-pair formation with 3-nitroaniline (3NO(2)A) for eight halogenoacetic acids (HAAs, 3a-h: TFA, TCA, TBA, DFA, DCA, DBA, MCA, and MBA), and five 2,2-dichloroalkanoic acids containing 3-8 carbon atoms (HAs, 5a-e: DCPA, DCBA, DCMBA, DCVA, and DCOA) have been determined in TOL at 298.1 K. The results obtained brought to evidence for HAAs the formation of ion-pairs with two different stoichiometries (base-acid, 1:1 or 1:2), while in contrast the HAs furnish only the 1:1 pairs. The different steric and electronic requirements of HAAs and HAs seem to be responsible for such an unlikely behavior. At the same time, the acid-catalyzed MRH of the (Z)-phenylhydrazone of 5-amino-3-be…
Síntesis de Protoberberinas y Ciclopentil-isoquinoleínas Dopaminérgicas, y Síntesis de Indenopiridinas Melatoninérgicas
2015
Resumen – Discusión de los resultados. En la presente Tesis Doctoral se han desarrollado diversas rutas de síntesis para la obtención de alcaloides isoquinoleínicos, con diferentes esqueletos, y de hexahidroindenopiridinas. Además se han realizado sus correspondientes ensayos farmacológicos, sobre distintas dianas biológicas basándonos en los resultados obtenidos previamente con este tipo de alcaloides de síntesis y/o aislados de la naturaleza, y de moléculas estructuralmente similares. Se ha observado, a lo largo de muchos años, que las IQ son uno de los metabolitos secundarios activos (MSA) más abundantes y de mayor interés farmacológico de los aislados en especies de la familia de las An…
Anatomiskās un fizioloģiskās izmaiņas mūžzaļo rododendru vienpumpura spraudeņos ar lapu rizoģenēzes laikā endofītiskās sēnes Calcarisporium arbuscula…
2015
Rododendri ir pasaulē ļoti plaši pieprasīti daiļdārzniecības krūmi, ko o izmanto gan privātos dārzos, gan pilsētu apstādījumos. Daļa rododendru šķirņu ir pieskaitāmas pie grūti apsakņojamām, dažādu iemeslu dēļ saknes neattīstās un spraudeņi bojājas, tādēļ būtiski ir noskaidrot apsakņošanās procesu ietekmējošos faktorus. Calcarisporium arbuscula ir rododendru sakņu endofītiskā sēne, kas izdalīta no šķirnes ‘Babītes Lavanda’ stāda saknēm. Līdzšinējie eksperimenti ar rododendru mikrodzinumiem in vitro kā arī ar mikrospraudeņiem ex vitro norāda uz šīs sēnes iespējamo pozitīvo ietekmi uz rododendru mikrodzinumu augšanu un adventīvo sakņu attīstību. Darba mērķis bija noskaidrot, vai un kā Calcari…
Un'iconografia "trasfigurata": da santa Cecilia di Riccardo Quartararo a Santa Barbara di Cristoforo Faffeo
2016
Il volume, concepito secondo una metodologia multidisciplinare, propone all'attenzione degli studiosi nuovi dati per la conoscenza di una tavola dipinta dell'ultimo quarto del XV secolo proveniente al Museo Diocesano di Palermo dalla Cattedrale; finora attribuita a Riccardo Quartararo e identificata come Santa Cecilia solo per la presenza dell'angelo musico, l'opera viene qui correttamente riconosciuta, dopo il restauro, come Santa Barbara per l'imponente torre a donjon retrostante e attribuita al pittore napoletano Cristoforo Faffeo sulla base non solo di analogie stilistico-formali, ma di evidenze tecnico-esecutive e scientifiche nel confronto con altre opere riferite allo stesso e al Qua…
Optimization of the Red Tilapia (Oreochromis spp.) Viscera Hydrolysis for Obtaining Iron-Binding Peptides and Evaluation of In Vitro Iron Bioavailabi…
2020
Iron deficiencies continue to cause significant health problems in vulnerable populations. A good strategy to combat mineral deficiency includes fortification with iron-binding peptides. This research aims to determine the optimal conditions to hydrolyze red tilapia viscera (RTV) using Alcalase 2.4 L and recovery of iron-binding protein hydrolysate. The result showed that under the optimal hydrolysis condition including pH 10, 60 °