Search results for "ALIM"

showing 10 items of 1991 documents

TNF-α blockade may lead to improvement of vascular function in psoriasis patients.

2021

Psoriasis is one of the most common chronic inflammatory skin diseases and at the same time a risk factor for cardiovascular disease. Interleukin-17A (IL-17A)-mediated inflammation in psoriasis may lead to vascular dysfunction. This study aimed at investigating whether anti-inflammatory treatment by tumor necrosis factor (TNF)-α blockade alters vascular function in psoriasis patients. A total of 11 patients with psoriasis who underwent treatment with either adalimumab (n = 8) or etanercept (n = 3), 10 healthy control individuals and 14 patients with coronary artery disease (CAD) were included in this study. Treatment response was assessed using the Psoriasis Area and Severity Index (PASI) s…

medicine.medical_specialtyDermatologyBiochemistryGastroenterologyEtanerceptCoronary artery diseasePsoriasis Area and Severity IndexInternal medicinePsoriasismedicineAdalimumabHumansPsoriasisRisk factorMolecular Biologybusiness.industryTumor Necrosis Factor-alphamedicine.diseaseBlockadeVasodilationVasoconstrictionChronic DiseaseTumor necrosis factor alphaTumor Necrosis Factor InhibitorsEndothelium Vascularbusinessmedicine.drugExperimental dermatologyREFERENCES
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Review of biologics in allergic contact dermatitis

2020

The resistant and recalcitrant nature of severe allergic contact dermatitis (ACD) makes its management challenging. With advances in the understanding of the cellular and molecular pathogenesis of ACD, newer therapeutic targets are becoming apparent. In particular, the use of biologics has gained momentum, given the specificity of their action. This article aims to review the presently available data on the use of biologics in ACD. English-language-based literature available on the use of biological therapy was thoroughly probed in the following databases as on October 14, 2019: PubMed, Google Scholar, The Cochrane library, Embase, Scopus, and EBSCO. The following keywords were used: "conta…

medicine.medical_specialtyDermatologyOmalizumabEtanercept030207 dermatology & venereal diseases03 medical and health sciences0302 clinical medicineUstekinumabmedicineAdalimumabHumansImmunology and Allergy030212 general & internal medicineAllergic contact dermatitisBiological Productsbusiness.industryPatch Testsmedicine.diseaseDermatologyDupilumabInfliximabTreatment OutcomeDermatitis Allergic ContactSecukinumabbusinessmedicine.drugContact Dermatitis
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Ingesta nutricional en pacientes afectados de esclerosis lateral amiotrófica una consulta ambulatoria de nutrición artificial en Portugal

2021

Introducción: La Esclerosis Lateral Amiotrófica (ELA) es una patología neurodegenerativa crónica y progresiva, que produce la muerte de las motoneuronas. Deriva en pérdida de peso, de masa muscular e incremento de deficiencias nutricionales. Existe relación entre la ingesta nutricional y la patogénesis de la ELA. El objetivo de este análisis fue describir las características sociodemográficas, antropométricas y clínicas junto con la ingesta nutricional en una muestra de pacientes portugueses afectados de ELA. Material y Métodos: Se realizó una anamnesis clínica breve. El peso corporal fue evaluado siguiendo el protocolo de la International Society for the Advancement of Kinanthropometry (IS…

medicine.medical_specialtyEsclerosis Amiotrófica LateralRC620-627ConstipationAntioxidantesWeight lossInternal medicinemedicineVitamin D and neurologyTX341-641Amyotrophic lateral sclerosisEstado NutricionalNutritional diseases. Deficiency diseasesAnamnesisNutrition and DieteticsPortugalNutrition. Foods and food supplybusiness.industryIngestión de AlimentosAnthropometrymedicine.diseaseMalnutritionDietary Reference Intakemedicine.symptombusinessFood ScienceRevista Española de Nutrición Humana y Dietética
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Exacerbation of ulcerative colitis after rituximab salvage therapy

2007

Background: B-cells are considered to play a pathogenic role in human ulcerative colitis (UC) by producing autoantibodies that cause epithelial cell damage. Here we report on a patient with intractable UC who suffered from a severe exacerbation of UC after salvage therapy with rituximab, a B-cell-depleting anti-CD20-antibody. Methods: A 58-year-old patient with active long-standing UC and unresponsiveness or adverse events to mesalamine, corticosteroids, azathioprine, methotrexate, infliximab, leukapheresis, mycophenolate mofetil, and adalimumab received 375 mg/m2 rituximab. Results: A severe exacerbation of UC activity was noted upon therapy that required hospitalization. Subsequent studie…

medicine.medical_specialtyExacerbationSalvage therapyAzathioprineGastroenterologyInflammatory bowel diseaseAntibodies Monoclonal Murine-DerivedInternal medicinemedicineAdalimumabHumansImmunology and AllergySalvage TherapyB-Lymphocytesbusiness.industryGastroenterologyAntibodies MonoclonalMiddle Agedmedicine.diseaseUlcerative colitisInfliximabInterleukin-10ImmunologyColitis UlcerativeRituximabRituximabbusinessmedicine.drugInflammatory Bowel Diseases
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Effect of propylene glycol on pre- and post-partum performance by dairy ewes

2005

This study was carried out in order to determine the effects, after feeding propylene glycol to Valle del Belice ewes 30 days prepartum and 30 days postpartum, on metabolic profiles, body-condition score, milk yield, milk composition, milk clotting ability and the performance of suckling lambs. Ewes were blocked by parity, body-condition score and previous milk production, and assigned randomly to either a control diet or a diet containing propylene glycol fed at the rate of 80 g/ewe/day (low PG) or 160 g/ewe/day (high PG). Feeding propylene glycol prepartum decreased the concentration of BHBA and NEFA and increased the concentration of glucose in the ewes’ plasma. Milk yield from ewes fed …

medicine.medical_specialtyMilk yieldMilk proteinChemistryKeywords: EweMilk productionPolyvinyl alcoholEwechemistry.chemical_compoundfluids and secretionsAnimal scienceMilk yieldEndocrinologyNEFAPropylene glycolFood AnimalsPostpartumInternal medicineMilk fatKeywords: Ewe Propylene glycol Prepartum Postpartum Milk yieldmedicineAnimal Science and ZoologyComposition (visual arts)PrepartumSettore AGR/18 - Nutrizione E Alimentazione Animale
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Nutritional Recovery Centers: 1984-2011

2020

Los centros de recuperación nutricional (CRN) fueron creados por el Dr. José María Bengoa en Venezuela. En el presente estudio se realizó una revisión sistemática cualitativa, de 1984 al 2011, que permitió analizar las modalidades de funcionamiento de los diferentes CRN en el mundo, mediante indicadores de: criterios de admisión, parámetros utilizados en estos centros, así como las modalidades de tratamiento, tiempo de estancia y criterios de alta. Se encontraron diecisiete artículos que describen algunos o todos estos indicadores. El uso de los CRN se encontró en cuatro países de África (Etiopía, Kenia, Malawi y Nigeria), cuatro de América (Bolivia, Brasil, Chile y Nicaragua) y dos en Asia…

medicine.medical_specialtyNutrition and Dieteticsbusiness.industryPublic healthInfants AlimentacióNutritional Rehabilitation CentersMedicine (miscellaneous)Centros de recuperación nutricionalChildhood undernutritionSalut públicaHistoria de la CienciaWastingDesnutrición agudaDesnutrición infantilSalud públicaMaternal and child educationEnvironmental healthmedicinePublic Healthmedicine.symptombusinessWastingNutricióEducación materno-infantil
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Efficacy of adalimumab as second-line therapy in a pediatric cohort of Crohn’s disease patients who failed infliximab therapy: the Italian Society of…

2019

Patrizia Alvisi,1 Serena Arrigo,2 Salvatore Cucchiara,3 Paolo Lionetti,4 Erasmo Miele,5 Claudio Romano,6 Alberto Ravelli,7 Daniela Knafelz,8 Stefano Martelossi,9 Graziella Guariso,10 Salvatore Accomando,11 Giovanna Zuin,12 Costantino De Giacomo,13 Lucio Balzani,14 Monia Gennari,15 Marina Aloi3 On behalf of the SIGENP IBD Working Group 1Pediatric Gastroenterology Unit, Pediatric Department, Maggiore Hospital, Bologna, Italy; 2Pediatric Gastroenterology and Endoscopy Unit, G Gaslini Children’s Hospital, Genoa, Italy; 3Pediatric Gastroenterology and Liver Unit, Sapienza University of Rome, Rome, Italy; 4Gastroenterology and Nutrition Unit, Meyer Children’s Hospital, Florenc…

medicine.medical_specialtyPopulationadalimumab efficacy03 medical and health sciences0302 clinical medicineadalimumab efficacy; adalimumab safety; infliximab failure; pediatric crohn’s diseaseRheumatologyInternal medicinemedicineAdalimumabinfliximab failureImmunology and AllergyTargets and Therapy [Biologics]Pharmacology (medical)Adverse effecteducationPediatric gastroenterologyOriginal ResearchCrohn's diseaseeducation.field_of_studybusiness.industryAdalimumab efficacy; Adalimumab safety; Infliximab failure; Pediatric Crohn’s disease; Immunology and Allergy; Rheumatology; Oncology; Gastroenterology; Pharmacology (medical)Gastroenterologyadalimumab safetyHepatologymedicine.diseaseInfliximabOncology030220 oncology & carcinogenesisCohortpediatric Crohn’s disease030211 gastroenterology & hepatologybusinessmedicine.drugBiologics : Targets & Therapy
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La nutrición en el periodo preconcepcional y los resultados del embarazo: revisión bibliográfica y propuesta de intervención del Dietista-Nutricionis…

2016

El estado nutricional de la madre antes y durante el embarazo se constata en los últimos años como uno de los factores ambientales más influyentes en el desarrollo fetal. Este estudio se centra en las primeras fases del proceso de gestación o periodo periconcepcional: preconcepción, concepción, implantación, placentación y embriogénesis; puesto que representan un paso crítico en los resultados del embarazo. Tras una revisión bibliográfica exhaustiva de 66 investigaciones publicadas entre los años 1990 y 2015, fueron el zinc, el hierro, el yodo, los ácidos grasos omega-3, el ácido fólico y otras vitaminas del grupo B, los minerales y micronutrientes para los que se han encontrado mayor evide…

medicine.medical_specialtyRC620-627OffspringEmbarazoIntervención médica tempranaBreastfeedingResultados del embarazoIntervención dietéticonutricional03 medical and health sciences0302 clinical medicinemedicineTX341-641030212 general & internal medicineNutritional diseases. Deficiency diseasesIntervención dietético-nutricionalPregnancyFetusDieta alimentos y nutrición030219 obstetrics & reproductive medicineNutrition and DieteticsObstetricsbusiness.industryNutrition. Foods and food supplyComplementos alimenticiosPlacentationFisiología nutricional durante el embarazomedicine.diseaseMicronutrientSurgeryB vitaminsGestationbusinessFood Science
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Management of biological therapies for chronic plaque psoriasis during COVID-19 emergency in Italy

2020

The coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, is creating an unprecedented global public health emergency with the continuous growth of infected individuals worldwide. Italy was one of the first European country to face the first wave of infection outside mainland China. The first case of COVID-19 was confirmed in Lombardy on February 20th , 2020, and subsequently, a rapid increase in the number of detected cases was observed, spreading through Italy and the rest of Europe.3 As of April 22nd , confirmed COVID-19 cases in Italy were 183,957.

medicine.medical_specialtyTildrakizumabBiolgical therapy; COVID-19; PsoriasisSettore MED/35PsoriasisChronic Disease; Emergencies; Humans; Italy; Psoriasis; Biological Therapy; COVID-19UstekinumabmedicineAdalimumabHumansPsoriasisbiologicsIntensive care medicineLetter to the Editorpsoriasipsoriasis; biologics; covid-19; pandemicEmergenciePsoriasiRisankizumabbusiness.industrySARS-CoV-2pandemicBiolgical therapyCOVID-19medicine.diseasedermatologyBiological TherapyIxekizumabGuselkumabInfectious Diseasescovid-19ItalyChronic DiseaseSecukinumabEmergenciesbusinessSettore MED/35 - MALATTIE CUTANEE E VENEREEbiologicCOVID-19 psoriasis biological therapiesmedicine.drugHuman
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The lyon clinical olfactory test: validation and measurement of hyposmia and anosmia in healthy and diseased populations.

2011

 ; International audience; The LCOT is a self-administered test designed to assess olfactory deficits. Altogether, 525 subjects contributed to the validation. Elderly participants were well represented in this sample. In a validation study (study 1), 407 healthy and 17 anosmic volunteers between 15 and 91 years of age underwent threshold, supraliminal detection, and identification testing. Cutoff values for normosmia and hyposmia were calculated and applied in a second study in a group of patients with smell complaints and in a group of Alzheimer patients with age-matched controls. Incidence of smell deficit was estimated at 5.6% in the healthy population of study 1, and at 16% in the elder…

medicine.medical_specialtyValidation studyArticle SubjectOlfactory disorderAnosmialcsh:SurgeryMédecine humaine et pathologieOlfactionTest validityAudiologyBioinformaticsaging;development;olfaction;olfactory disorder;Alzheimer's disease;cognitive impairment03 medical and health sciences0302 clinical medicineHyposmiamedicineFood and Nutrition[SDV.MHEP.OS]Life Sciences [q-bio]/Human health and pathology/Sensory Organs030223 otorhinolaryngologyolfactory disorderdevelopmentcognitive impairmentbusiness.industryIncidence (epidemiology)Healthy populationaging[ SDV.SPEE ] Life Sciences [q-bio]/Santé publique et épidémiologielcsh:RD1-811Alzheimer's diseaselcsh:Otorhinolaryngologylcsh:RF1-547[SDV.MHEP.OS] Life Sciences [q-bio]/Human health and pathology/Sensory Organs[SDV.SPEE] Life Sciences [q-bio]/Santé publique et épidémiologie[ SDV.MHEP.OS ] Life Sciences [q-bio]/Human health and pathology/Sensory OrgansAlimentation et NutritionNeurosciences (Sciences cognitives)Human health and pathology[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologiemedicine.symptombusiness030217 neurology & neurosurgeryResearch ArticleNeuroscienceolfaction
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