Search results for "ALK"
showing 10 items of 4314 documents
Neuromuscular Training Warm-up Prevents Acute Noncontact Lower Extremity Injuries in Children’s Soccer : A Cluster Randomized Controlled Trial
2021
Background: Prevention of sports injuries is essential in youth, as injuries are associated with less future physical activity and thus greater all-cause morbidity. Purpose: To investigate whether a neuromuscular training warm-up operated by team coaches is effective in preventing acute lower extremity (LE) injuries in competitive U11-U14 soccer players. Study Design: Randomized controlled trial; Level of evidence, 1. Methods: Twenty top-level U11 to U14 soccer clubs in Finland were randomized into intervention and control groups and assessed for 20 weeks. Participants included 1403 players (280 female, 1123 male; age range, 9-14 years): 673 players (44 teams) in the intervention group and …
Effects of concurrent strength and endurance training in women with early or longstanding rheumatoid arthritis: Comparison with healthy subjects
2003
Objective To investigate the effects of a 21-week concurrent strength and endurance training protocol on physical fitness profile in women with early or longstanding rheumatoid arthritis (RA) compared with healthy subjects. Methods Twenty-three female patients with RA volunteered for the study. Twelve had early RA and eleven had longstanding RA. Twelve healthy women served as controls. Maximal strength of different muscle groups was measured by dynamometers, walking speed with light cells, and vertical squat jump on the force platform to mirror explosive force. Maximal oxygen uptake was measured by gas analyzer. Six training sessions (3 strength training and 3 endurance training) were carri…
Prevalence and Clinical Outcomes for Patients With ALK Gene Rearrangement in Europe: Preliminary Results from the European Thoracic Oncology Platform…
2012
ABSTRACT Background The prevalence of ALK gene rearrangement (ALK+) in European patients with non-small cell lung cancer (NSCLC) is unknown. The Lungscape project provides a platform to evaluate its expression and clinical significance in a large cohort of patients with resected NSCLC from 13 European sites in 11 countries. Methods Participating sites retrospectively identified cases of NSCLC with clinical demographic and outcome data, and available tissue for research according to predefined protocol criteria. Local ethical and regulatory approvals were adhered to. Clinical data were entered to a central, secure database. Accepted cases on the basis of completeness of clinical data were as…
Evaluation of low-dose metronomic (LDM) cyclophosphamide toxicity in cats with malignant neoplasia
2014
Oral administration of low-dose cyclophosphamide in pets with spontaneously occurring malignant neoplasms has become a common practice in veterinary medicine. The purpose of this retrospective study was to investigate toxicity events in cats with spontaneous malignancies receiving cyclophosphamide as a metronomic therapy for at least 1 month. The number and severity of clinical, haematological and biochemical adverse events were recorded according to the Veterinary Cooperative Oncology Group’s Common Terminology Criteria for Adverse Events v1.1 classification scheme. Twenty-four cats were enrolled in the study with a total number of 27 neoplasms: 13 sarcomas, 12 carcinomas, one melanoma an…
Effects of strength and endurance training on thigh and leg muscle mass and composition in elderly women
1995
The effects of 18 wk of intensive strength and endurance training on knee extensor, knee flexor, and lower leg muscle mass and composition were studied in 76- to 78-yr-old women. Muscle cross-sectional area (CSA), lean tissue CSA, and relative proportion of fat were determined using computed tomography. The strength-trained women increased their total muscle lean tissue CSA of the thigh (1.5%; P = 0.035), quadriceps CSA (4.5%; P = 0.021), quadriceps lean tissue CSA (5.8%, P = 0.009), and mean Hounsfield unit of the lower leg muscles (11.2%; P = 0.035) compared with the changes that occurred in the control group during the experiment. The change in quadriceps lean tissue CSA because of the …
Effects of Strength Training on Muscle Strength Characteristics, Functional Capabilities, and Balance in Middle-Aged and Older Women
2006
Progressive strength training can lead to substantial increases in maximal strength and mass of trained muscles, even in older women and men, but little information is available about the effects of strength training on functional capabilities and balance. Thus, the effects of 21 weeks of heavy resistance training--including lower loads performed with high movement velocities--twice a week on isometric maximal force (ISOmax) and force-time curve (force produced in 500 milliseconds, F0-500) and dynamic 1 repetition maximum (1RM) strength of the leg extensors, 10-m walking time (10WALK) and dynamic balance test (DYN.D) were investigated in 26 middle-aged (MI; 52.8 +/- 2.4 years) and 22 older …
A School-Based Randomized Controlled Trial to Promote Cycling to School in Adolescents: The PACO Study
2021
This manuscript describes the rationale and protocol of a school-based randomized controlled trial called “Cycling and Walk to School” (PACO, by its Spanish acronym) that aims to promote cycling to and from school and physical activity (PA) in adolescents. This study will examine the effects of this intervention in cycling and active commuting to and from school (ACS), PA and several ACS-related factors based on self-determination theory (SDT) and a social-ecological model (SEM). A total of 360 adolescents attending six high schools (three experimental and three control) from three Spanish cities will participate in this randomized controlled trial. The intervention (four cycling sessions; …
Cardiorespiratory responses to basic aquatic exercise – A pilot study
2006
This study aimed to examine cardiorespiratory responses to six basic aquatic exercises and to compare the impact of the exercises between healthy females (H group, n=10) and females with diagnosed cardiopulmonary diseases (C group, n=10). The average age of the participants was 52.6(±5.9) years. Each exercise was performed for 3 min. During the exercises, heart rate (HR), oxygen consumption (VO2), blood lactate concentration (BLA), and rate of perceived exertion (RPE) were measured. In each pair of exercises, the latter part was more strenuous than the first. Walking in place was least and cross-country skiing the most strenuous mode of exercise. Energy expenditure (EE) ranged between 2.5±0…
THERAPEUTIC AND COLATERAL EFFECTS OF 25-HYDRXYCHOLECAICI FEROL IN VITAMIN D DEFICIENCY
1974
Vitamin D polar metabolite, 25–HCC has been used in 2 infant groups whose ages range from 0–18 months. In the 1st group of 15 infants, all of them suffered from rickets, clinically, biochemistry and radiologically and no prophylactic vitamin D administration could be demonstrated. The control group (15 infants too) was admitted with similar diseases but no one suffered from rickets. Routine determinations for metabolic assesment of Ca phosphoric metabolism were perforaed in plasma and in 240. urine collections, prior and after 25–HCC adBinietration. The rickets group received 20 mcg/day, orally for 20 days and the control 10mcg/day in the same way. The biochemical study demonstrated that bo…
The effect of conventional movement training and trampoline training on balance and gait in chronic hemiplegic patients
1991
The postural sway of subjects during standing both with their eyes open and closed together with maximum velocity of walking were analysed in six male chronic hemiplegic patients before, during and after an intensive movement training programme lasting 8 weeks. The movement training programme was carried out on the basis of Bobath's principles. Three of the subjects carried out their training on a trampoline, with the particular purpose of enhancing the stimulation of the mechanisms responsible for the control of balance. During the follow-up, maximal walking velocity remained at previous levels and no systematic changes were observed in the control of postural sway. Although the use of the…