Search results for "ALK"

showing 10 items of 4314 documents

Effects of prolonged and maintenance strength training on force production, walking, and balance in aging women and men

2012

To examine effects of 21-week twice/week strength training (ST) period followed by an additional 21-week twice or once/week ST period on force production, walking and balance in aging people. Seventy-two women (58 ± 7 years; W) and 63 (58 ± 6 years) men (M) were randomized for the first 21-week ST period: STW and STM, control (C) CW and CM. Training participants were randomized for the second 21-week ST period: once/week STWx1 and STMx1, twice/week STWx2 and STMx2. LegPress, isometric leg extension rate of force development (RFD), walking time, and balance. First 21-week ST period: leg press, RFD, balance, and walking improved significantly in STW and STM. Second 21-week ST period: leg pres…

medicine.medical_specialtybusiness.industryStrength trainingPhysical Therapy Sports Therapy and RehabilitationIsometric exerciseWalking timePhysical medicine and rehabilitationRate of force developmentMaximal strengthPhysical therapyMedicineOrthopedics and Sports MedicineLeg extensionLeg pressbusinessBalance (ability)Scandinavian Journal of Medicine & Science in Sports
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Glutathione, GlutathioneS-Transferase α and π, and Aldehyde Dehydrogenase Content in Relationship to Drug Resistance in Ovarian Cancer

1997

Glutathione, glutathione S-transferases alpha and pi, and aldehyde dehydrogenase are associated with resistance to carboplatin and/or cyclophosphamide in cell lines. Therefore, we examined whether the expression of these factors in ovarian cancer tissue specimens is associated with resistance of the patients to combination chemotherapy with cyclophosphamide/carboplatin. Ovarian cancer tissue specimens were taken intraoperatively from 139 patients and frozen in liquid nitrogen, and the contents of glutathione S-transferases alpha and pi, total glutathione, and aldehyde dehydrogenase activity were determined. No association between the levels of glutathione S-transferases alpha and pi or alde…

medicine.medical_specialtyendocrine system diseasesCyclophosphamidemedicine.medical_treatmentBlotting WesternAldehyde dehydrogenaseAntineoplastic AgentsOvaryCarboplatinchemistry.chemical_compoundInternal medicineHumansMedicineAntineoplastic Agents AlkylatingCyclophosphamideGlutathione TransferaseNeoplasm StagingOvarian NeoplasmsChemotherapybiologybusiness.industryObstetrics and GynecologyCombination chemotherapyGlutathioneAldehyde DehydrogenasePrognosismedicine.diseaseCombined Modality TherapyGlutathioneDrug Resistance Multiplefemale genital diseases and pregnancy complicationsCarboplatinmedicine.anatomical_structureEndocrinologyOncologychemistryDrug Resistance Neoplasmbiology.proteinCancer researchDrug Therapy CombinationFemaleCisplatinbusinessOvarian cancermedicine.drugGynecologic Oncology
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Effects of Topical Hydrogen Purification on Skin Parameters and Acne Vulgaris in Adult Women

2021

Background: Acne vulgaris is a prevalent dermatological disease characterized by skin eruptions, which may decrease the sufferer’s quality of life. Hydrogen purification treatment is a new procedure used in cosmetology to improve the skin parameters of the face. This study examined the effectiveness of hydrogen purification treatment to improve women’s skin conditions with regard to acne vulgaris. Methods: In this study, 30 women participated who suffered from a high level of sebum and acne. The control group was comprised of 30 healthy women with a low level of sebum. The Hellgren–Vincent Scale and Derma Unit SSC 3 device were used to assess acne vulgaris severity and skin properties, resp…

medicine.medical_specialtyhydrogen purificationLeadership and Managementlcsh:MedicineHealth InformaticsAlkaline waterHydrogen purifierArticleAdult women030207 dermatology & venereal diseases03 medical and health sciences0302 clinical medicineHealth Information Managementmedicineacne vulgaris030212 general & internal medicineAcneintegumentary systembusiness.industryHealth Policylcsh:Rmedicine.diseaseDermatologyalkaline waterCosmetologybusinessHealthcare
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Exploring Potential Benefits of Accumulated Multicomponent-Training in Non-Active Older Adults: From Physical Fitness to Mental Health

2021

The present study aimed to analyze the impact of a multicomponent training (MCT) program in a group of non-active older adults, comparing two different dose distributions. Twenty-four individuals, assigned to two groups, completed 15 weeks of MCT (2 days/week). The continuous group (CMCT

medicine.medical_specialtyinstrumental activities of daily lifePost hocHealth Toxicology and Mutagenesisactive agingPhysical fitnessPhysical exerciseDose distributionPhysical functionwalking speedelderlywellnessArticlephysical exercisesedentary behaviorMedicineHumansExerciseMorningAgedbusiness.industryPublic Health Environmental and Occupational HealthRCardiorespiratory fitnessExercise TherapyPreferred walking speedMental Healthexecutive functionPhysical FitnessPhysical therapyQuality of LifeMedicineFemalebusinessstrengthInternational Journal of Environmental Research and Public Health
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Nutritional self-care among a group of older home-living people in rural Southern Norway

2015

Bjørg Dale, Ulrika SöderhamnCentre for Caring Research – Southern Norway, Faculty of Health and Sport Sciences, University of Agder, Grimstad, NorwayBackground: Older home-living people are an at-risk group for undernutrition, particularly those who are living alone. Lack of knowledge about healthy dietary habits, altered taste sensation, and declined health status are shown to be some of the factors related to undernutrition. The aims of this study were to explore how a small group of older people in Southern Norway perceived their nutritional self-care.Methods: An exploratory qualitative approach, combined with a simple self-report questionnaire, was used. Fi…

medicine.medical_specialtyknowledgespørreskjematilpasningsevnehjemmeboendeNorgeVDP::Medical disciplines: 700::Health sciences: 800::Nutrition: 811adaptingMultidisciplinary approachHealth careeldreMedicineernæringsstatusGeneral NursingOriginal Researchintervjupasientsikkerhetegenomsorgbusiness.industryJournal of Multidisciplinary HealthcaresamtaleGeneral Medicinedecision-makingunderernæringData sciencePeer reviewself-care talksFamily medicineSelf carediettkunnskapbusinesskostholdernæring
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Association between frontal plane knee control and lower extremity injuries : a prospective study on young team sport athletes

2017

Background/aimPoor frontal plane knee control can manifest as increased dynamic knee valgus during athletic tasks. The purpose of this study was to investigate the association between frontal plane knee control and the risk of acute lower extremity injuries. In addition, we wanted to study if the single-leg squat (SLS) test can be used as a screening tool to identify athletes with an increased injury risk.MethodsA total of 306 basketball and floorball players participated in the baseline SLS test and a 12-month injury registration follow-up. Acute lower extremity time-loss injuries were registered. Frontal plane knee projection angles (FPKPA) during the SLS were calculated using a two-dimen…

medicine.medical_specialtykoripalloTeam sportknee injuriespolvetPhysical Therapy Sports Therapy and RehabilitationSquat03 medical and health sciences0302 clinical medicinePhysical medicine and rehabilitationanklemedicineOrthopedics and Sports Medicine1506Risk factorProspective cohort studyurheilusuorituksetohjaus (hallinta)030222 orthopedicsbiologybusiness.industryAthletes030229 sport scienceskyykytbiology.organism_classificationjalatraajatValgussuuntaaminensquatsmedicine.anatomical_structurerisk factorCoronal planejalkapalloOriginal ArticlevammatAnklebusinesssporting injuriesloukkaantuminen (fyysinen)
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Stability and Predictors of Poor 6-min Walking Test Performance over 2 Years in Patients with COPD

2020

Poor performance in the 6-min walk test (6MWT &lt

medicine.medical_specialtylcsh:MedicinePulmonary diseaseLogistic regressionArticlemobility activities03 medical and health sciences0302 clinical medicineInternal medicine6MWTMedicineCOPDIn patient030212 general & internal medicinePrognostic modelsCOPDPerformance statusbusiness.industrylcsh:RGeneral Medicinemedicine.disease5STSpredictors030228 respiratory systemTest scorebusiness6 min walking testJournal of Clinical Medicine
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Environmental facilitators for outdoor walking and development of walking difficulty in community-dwelling older adults

2013

Older adults who report environmental barriers in their neighborhood have a higher risk for walking difficulty. However, environmental facilitators that protect against walking difficulty are not well known. The objective of this study was to identify the effect of environmental facilitators for outdoor walking on development of walking difficulty in community-dwelling older people. This was a prospective study with a 3.5-year follow-up time on 261 community-dwelling people aged 75–81 years, who at baseline were able to walk 0.5 km without difficulty. Environmental facilitators for outdoor walking were self-reported with standardized questionnaires, including having features in one’s home w…

medicine.medical_specialtyliikkumiskykyHealth (social science)ympäristöGeriatrics gerontologyulkona liikkuminenPhysical activityoutdoor walkingwalking difficultyWalking distancekävelyvaikeusPhysical medicine and rehabilitationDifficulty walkingliikkuvuusFacilitatormedicineEnvironmental facilitatorsGeriatrics and GerontologyOlder peoplePsychologyRecreationhuman activitiesOriginal Investigation
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Leg extension power asymmetry and mobility limitation in healthy older women

2005

Objective To investigate the association of asymmetry in leg extension power (LEP) with walking and standing balance. Design Cross-sectional analysis. Setting Research laboratory. Participants Healthy female twins (N=419), ages 63 to 75 years. Interventions Not applicable. Main Outcome Measures The LEP difference between the stronger and the weaker leg, measured with the Nottingham power rig, was calculated. Ten-meter maximal walking velocity was assessed in a laboratory corridor on a wide (170cm) and narrow (35cm) track, and the ability to maintain tandem stance for 20 seconds was recorded. Results The mean LEP difference ± standard deviation between the legs was 15%±9% (P<.001). Those wit…

medicine.medical_specialtyliikkumiskykyPower asymmetrymedicine.medical_treatmentMusculoskeletal Physiological PhenomenaeducationTwinsPhysical Therapy Sports Therapy and RehabilitationWalkingSensitivity and SpecificityStandard deviation03 medical and health sciences0302 clinical medicineReference ValuesWalking velocitymedicineHumans030212 general & internal medicineRange of Motion ArticularMuscle SkeletalPostural Balancehealth care economics and organizationsAgedProbabilityAnalysis of VarianceRehabilitationbusiness.industryRehabilitationAge FactorsMiddle AgedBiomechanical PhenomenaStanding balanceCross-Sectional StudiesLower ExtremityMobility LimitationPhysical FitnessMuscle powerPhysical therapyFemaleLeg extensionbusinessalaraajojen voimantuottoteho030217 neurology & neurosurgerypuolierohormones hormone substitutes and hormone antagonists
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Drug-induced hepatitis: a rare complication of oral anticoagulants.

1994

Hepatotoxicity is a rare complication of coumarin anticoagulants. We present the case of a 56-year-old woman who developed a viral-hepatitis-like picture 8 months after mitral valve replacement and oral anticoagulation. Phenprocoumon-induced hepatitis was diagnosed after positive reexposure and improvement following withdrawal of the drug. There appeared to be cross-reactivity to warfarin since this drug led to a similar increase in alkaline phosphatase and gamma-glutamyl transferase after a few days of administration. Liver biopsy showed an acute viral-hepatitis-like picture. Anticoagulation was changed to a subcutaneous low molecular weight heparin and low-dose aspirin. Because of the wid…

medicine.medical_specialtymedicine.drug_classBiopsyLow molecular weight heparinAdministration OralGastroenterologyInternal medicinemedicineHumansHepatitisAspirinHepatologymedicine.diagnostic_testbusiness.industryIncidenceAnticoagulantWarfaringamma-GlutamyltransferaseMiddle Agedmedicine.diseaseAlkaline PhosphataseSurgeryLiverLiver biopsyPhenprocoumonFemaleWarfarinChemical and Drug Induced Liver InjurybusinessViral hepatitisComplicationmedicine.drugJournal of hepatology
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