Search results for "ALTERS"

showing 10 items of 42 documents

The preference and costs of sleeping under light at night in forest and urban great tits

2019

Artificial light at night (ALAN) is an increasing phenomenon associated with worldwide urbanization. In birds, broad-spectrum white ALAN can have disruptive effects on activity patterns, metabolism, stress response and immune function. There has been growing research on whether the use of alternative light spectra can reduce these negative effects, but surprisingly, there has been no study to determine which light spectrum birds prefer. To test such a preference, we gave urban and forest great tits (Parus major) the choice where to roost using pairwise combinations of darkness, white light or green dim light at night (1.5 lux). Birds preferred to sleep under artificial light instead of dar…

0106 biological sciencesMaleLight pollutionForestsartificial light at night01 natural sciencesoxalic acidSleep debtOxalic acidParus majorPasseriformesGeneral Environmental Sciencevuorokausirytmi0303 health sciencesbiologyBehavior Animallight pollutionGeneral MedicinetalitiainenPE&RCSleep in non-human animalsPreferenceCircadian RhythmLight pollutioninternationalMAMMALSDarknessFemalekaupungistuminenGeneral Agricultural and Biological SciencesBEHAVIORenergiankulutus (aineenvaihdunta)ZoologyurbanizationAnimal Breeding and Genomics010603 evolutionary biologyGeneral Biochemistry Genetics and Molecular Biologyuni (lepotila)03 medical and health sciencesBiointeractions and Plant HealthAnimalsCOLORBehaviourFokkerij en GenomicaCircadian rhythmsleepPHYSIOLOGYARTIFICIAL-LIGHTLighting030304 developmental biologyParusWhite (horse)BIRDSGeneral Immunology and MicrobiologyINTENSITYMEMORYUrbanizationPERFORMANCEbiology.organism_classificationvalosaasteEnergy MetabolismEnvironmental PollutionSleepArtificial light at nightALTERS
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The influence of serotonin- and other genes on impulsive behavioral aggression and cognitive impulsivity in children with attention-deficit/hyperacti…

2008

Contains fulltext : 70708.pdf (Publisher’s version ) (Open Access) ABSTRACT: BACKGROUND: Low serotonergic (5-HT) activity correlates with increased impulsive-aggressive behavior, while the opposite association may apply to cognitive impulsiveness. Both types of impulsivity are associated with attention-deficit/hyperactivity disorder (ADHD), and genes of functional significance for the 5-HT system are implicated in this disorder. Here we demonstrate the separation of aggressive and cognitive components of impulsivity from symptom ratings and test their association with 5-HT and functionally related genes using a family-based association test (FBAT-PC). METHODS: Our sample consisted of 1180 o…

2805 Cognitive Neurosciencemedicine.medical_specialtyNeurologyGenetics and epigenetic pathways of disease [NCMLS 6]Cognitive NeuroscienceMedizin610 Medicine & healthNeuroinformatics [DCN 3]SerotonergicImpulsivityMental health [NCEBP 9]lcsh:RC346-429Genomic disorders and inherited multi-system disorders [IGMD 3]03 medical and health sciencesBehavioral Neuroscience0302 clinical medicineCognitive neurosciences [UMCN 3.2]2802 Behavioral NeurosciencePerception and Action [DCN 1]medicineAttention deficit hyperactivity disorderddc:610Medizinische Fakultät » Universitätsklinikum Essen » LVR-Klinikum Essen » Klinik für Psychiatrie Psychosomatik und Psychotherapie des Kindes- und JugendaltersAssociation (psychology)Psychiatrylcsh:Neurology. Diseases of the nervous systemBiological PsychiatryAggressionResearchCognitionGeneral Medicine10058 Department of Child and Adolescent Psychiatrymedicine.disease030227 psychiatryAutism spectrum disordermedicine.symptomPsychologyFunctional Neurogenomics [DCN 2]2803 Biological Psychiatry030217 neurology & neurosurgeryClinical psychology
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Latvijas Zinātņu akadēmijas akadēmiķis, profesors Raimonds Valters : biobibliogrāfija

2008

Latvijas Zinātņu akadēmijas akadēmiķa, Rīgas Tehniskās universitātes profesora R. Valtera biobibliogrāfija aptver laika posmu no 1959. gada līdz 2008. gada martam

:NATURAL SCIENCES::Chemistry::Organic chemistry [Research Subject Categories]BiogrāfijasBiobibliogrāfijasValters RaimondsĶīmiķi. Latvija
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German validation of the conners adult ADHD rating scale-self-report: confirmation of factor structure in a large sample of participants with ADHD.

2013

Objective: The Conners Adult ADHD Rating Scales (CAARS) assess symptoms specific to adults that are frequently used and have been translated into German. The current study tests the factor structure of the CAARS in a large sample of German adults with ADHD and compares the means of the CAARS subscales with those of healthy German participants. Method: CAARS were completed by 466 participants with ADHD and 851 healthy control participants. Confirmatory factor analysis was used to establish model fit with the American original. Comparisons between participants with ADHD and healthy controls and influences of gender, age, and degree of education were analyzed. Results: Confirmatory factor anal…

AdultMalemedicine.medical_specialtyMedizinFactor structurebehavioral disciplines and activitiesGermanConners Adult ADHD Rating Scales (CAARS)diagnostic issuesRating scaleGermanyHealthy controlmental disordersDevelopmental and Educational Psychologymedicineadult ADHD assessmentADHDHumansddc:610Medizinische Fakultät » Universitätsklinikum Essen » LVR-Klinikum Essen » Klinik für Psychiatrie Psychosomatik und Psychotherapie des Kindes- und JugendaltersPsychiatrySelf reportadult ADHDMiddle AgedConfirmatory factor analysislanguage.human_languageLarge sampleClinical PsychologyAttention Deficit Disorder with HyperactivitylanguageFemaleSelf ReportPsychologyJournal of attention disorders
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Analysis of thiamine transporter genes in sporadic beriberi

2014

Abstract Objective Thiamine or vitamin B 1 deficiency diminishes thiamine-dependent enzymatic activity, alters mitochondrial function, impairs oxidative metabolism, and causes selective neuronal death. We analyzed for the first time, the role of all known mutations within three specific thiamine carrier genes, SLC19 A2, SLC19 A3 , and SLC25 A19 , in a patient with atrophic beriberi, a multiorgan nutritional disease caused by thiamine deficiency. Methods A 44-year-old male alcoholic patient from Morocco developed massive bilateral leg edema, a subacute sensorimotor neuropathy, and incontinence. Despite normal vitamin B 1 serum levels, his clinical picture was rapidly reverted by high-dose in…

AdultMalemedicine.medical_specialtySLC19 A- SLC25 A19SLC19 AEndocrinology Diabetes and MetabolismGene mutationBeriberimedicine.disease_causeMitochondrial Membrane Transport Proteinslaw.inventionBeriberilawInternal medicineGenotypemedicineThiamine transporterObjective: Thiamine or vitamin B1 deficiency diminishes thiamine-dependent enzymatic activity alters mitochondrial function impairs oxidative metabolism and causes selective neuronal death. We analyzed for the first time the role of all known mutations within three specific thiamine carrier genes SLC19 A2 SLC19 A3 and SLC25 A19 in a patient with atrophic beriberi a multiorgan nutritional disease caused by thiamine deficiency. Methods: A 44-year-old male alcoholic patient from Morocco developed massive bilateral leg edema a subacute sensorimotor neuropathy and incontinence. Despite normal vitamin B1 serum levels his clinical picture was rapidly reverted by high-dose intramuscular thiamine treatment suggesting a possible genetic resistance. We used polymerase chain reaction followed by amplicon sequencing to study all the known thiamine-related gene mutations identified within the Human Gene Mutation Database. Results: Thirty-seven mutations were tested: 29 in SLC19 A2 6 in SLC19 A3 and 2 in SLC25 A19. Mutational analyses showed a wild-type genotype for all sequences investigated. Conclusion: This is the first genetic study in beriberi disease. We did not detect any known mutation in any of the three genes in a sporadic dry beriberi patient. We cannot exclude a role for other known or unknown mutations in the same genes or in other thiamine-associated genes in the occurrence of this nutritional neuropathy.HumansThiamineGenePolymerase chain reactionGeneticsMutationNutrition and DieteticsbiologyMembrane Transport ProteinsThiamine Deficiencymedicine.diseaseAlcoholismEndocrinologyMutationbiology.proteinThiamineMutations
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The analysis of 51 genes in DSM-IV combined type attention deficit hyperactivity disorder: association signals in DRD4, DAT1 and 16 other genes.

2006

Contains fulltext : 35205.pdf (Publisher’s version ) (Closed access) Attention deficit hyperactivity disorder (ADHD) is a common neurodevelopmental disorder, starting in early childhood and persisting into adulthood in the majority of cases. Family and twin studies have demonstrated the importance of genetic factors and candidate gene association studies have identified several loci that exert small but significant effects on ADHD. To provide further clarification of reported associations and identify novel associated genes, we examined 1,038 single-nucleotide polymorphisms (SNPs) spanning 51 candidate genes involved in the regulation of neurotransmitter pathways, particularly dopamine, nor…

Candidate geneGenetics and epigenetic pathways of disease [NCMLS 6]MedizinReceptors NicotinicTryptophan HydroxylaseNeuroinformatics [DCN 3]0302 clinical medicinePerception and Action [DCN 1]Determinants in Health and Disease [EBP 1]ChildOncogene ProteinsGenetics0303 health sciencesbiologyDNA POOLING ANALYSISPedigree3. Good healthserotoninPsychiatry and Mental healthConduct disorderChild Preschool/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingMonoamine oxidase AdopaminePsychologyFunctional Neurogenomics [DCN 2]Genetic MarkersAdolescentSynaptosomal-Associated Protein 25Single-nucleotide polymorphismassociation studyPolymorphism Single NucleotideMental health [NCEBP 9]Genetic determinismGenomic disorders and inherited multi-system disorders [IGMD 3]03 medical and health sciencesCellular and Molecular NeuroscienceMONOAMINE-OXIDASE-ACognitive neurosciences [UMCN 3.2]SDG 3 - Good Health and Well-beingmental disordersmedicineHumansAttention deficit hyperactivity disorderADHDGenetic Predisposition to Disease5-HT1B RECEPTOR GENEddc:610Medizinische Fakultät » Universitätsklinikum Essen » LVR-Klinikum Essen » Klinik für Psychiatrie Psychosomatik und Psychotherapie des Kindes- und JugendaltersMonoamine OxidaseMolecular Biology030304 developmental biologyGenetic associationDopamine Plasma Membrane Transport ProteinsSEROTONIN TRANSPORTER GENEDOPAMINE-BETA-HYDROXYLASESiblingsReceptors Dopamine D4candidate genemedicine.diseaseTwin studyPREFERENTIAL TRANSMISSIONHaplotypesCATECHOL-O-METHYLTRANSFERASEAttention Deficit Disorder with HyperactivityCONDUCT DISORDERbiology.proteinnoradrenalineDEFICIT/HYPERACTIVITY DISORDERNO EVIDENCE030217 neurology & neurosurgerylinkage disequilibriumMolecular Psychiatry
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Genome-wide association scan of attention deficit hyperactivity disorder

2008

Contains fulltext : 70191.pdf (Publisher’s version ) (Closed access) Results of behavioral genetic and molecular genetic studies have converged to suggest that genes substantially contribute to the development of attention deficit/hyperactivity disorder (ADHD), a common disorder with an onset in childhood. Yet, despite numerous linkage and candidate gene studies, strongly consistent and replicable association has eluded detection. To search for ADHD susceptibility genes, we genotyped approximately 600,000 SNPs in 958 ADHD affected family trios. After cleaning the data, we analyzed 438,784 SNPs in 2,803 individuals comprising 909 complete trios using ADHD diagnosis as phenotype. We present t…

Candidate geneLinkage disequilibriumGenetics and epigenetic pathways of disease [NCMLS 6]Medizin2804 Cellular and Molecular NeuroscienceGenome-wide association studyNeuroinformatics [DCN 3]Linkage Disequilibrium2738 Psychiatry and Mental Health0302 clinical medicinePerception and Action [DCN 1]Genetics(clinical)ChildGenetics (clinical)Genetics0303 health sciencesHomozygote10058 Department of Child and Adolescent PsychiatrySNP genotypingPsychiatry and Mental healthChild PreschoolData Interpretation Statistical/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingFunctional Neurogenomics [DCN 2]Algorithms2716 Genetics (clinical)AdolescentSingle-nucleotide polymorphism610 Medicine & healthBiologyMental health [NCEBP 9]Polymorphism Single NucleotideGenetic determinismArticleGenomic disorders and inherited multi-system disorders [IGMD 3]03 medical and health sciencesCellular and Molecular NeuroscienceCognitive neurosciences [UMCN 3.2]SDG 3 - Good Health and Well-beingmedicineSNPAttention deficit hyperactivity disorderHumansddc:610Medizinische Fakultät » Universitätsklinikum Essen » LVR-Klinikum Essen » Klinik für Psychiatrie Psychosomatik und Psychotherapie des Kindes- und JugendaltersAlleles030304 developmental biologyGenome Humanmedicine.diseaseGenetic defects of metabolism [UMCN 5.1]Attention Deficit Disorder with HyperactivityCase-Control Studies030217 neurology & neurosurgeryGenome-Wide Association Study
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Association between DRD2/DRD4 interaction and conduct disorder: a potential developmental pathway to alcohol dependence

2013

1 Department of Genetics, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil 2 King’s College London, Institute of Psychiatry, MRC Social Genetic and Developmental Psychiatry Centre, London, United Kingdom, UK 3 Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany 4 Department of Cognitive Neuroscience, Donders Institute for Brain, Cognition and Behavior, Radboud University Medical Center, Nijmegen, The Netherlands 5 Psychology Department, National University of Singapore, Singapore, Singapore 6 Department of Psychiatry, Donders Institute for Brain, Cognition an…

Conduct DisorderMalemedicine.medical_specialty2716 Genetics (clinical)AdolescentMedizin2804 Cellular and Molecular Neuroscience610 Medicine & healthComorbidityGenomic disorders and inherited multi-system disorders DCN MP - Plasticity and memory [IGMD 3]03 medical and health sciencesCellular and Molecular Neuroscience2738 Psychiatry and Mental Health0302 clinical medicineChild and adolescent psychiatrymedicineHumansddc:61Psychiatric hospitalddc:610Medizinische Fakultät » Universitätsklinikum Essen » LVR-Klinikum Essen » Klinik für Psychiatrie Psychosomatik und Psychotherapie des Kindes- und JugendaltersSociologyDCN PAC - Perception action and control NCEBP 9 - Mental healthChildGenetics (clinical)030304 developmental biology0303 health sciencesPolymorphism GeneticReceptors Dopamine D2Receptors Dopamine D4Alcohol dependenceEducational psychologyGenomic disorders and inherited multi-system disorders [DCN PAC - Perception action and control IGMD 3]10058 Department of Child and Adolescent PsychiatryPrognosismedicine.diseaseMental healthhumanities3. Good healthAlcoholismPsychiatry and Mental healthClinical neuropsychologyHealth psychologyConduct disorderFamily medicineFemale030217 neurology & neurosurgery
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A functional variant of the serotonin transporter gene (SLC6A4) moderates impulsive choice in attention-deficit/hyperactivity disorder boys and sibli…

2011

Item does not contain fulltext BACKGROUND: Impulsive drive for immediate reward (IDIR) and delay aversion are dissociable elements of the preference for immediate over delayed rewards seen in attention-deficit/hyperactivity disorder (ADHD). We hypothesized that IDIR would be associated with dopamine regulating genes and delay aversion would be associated with serotonin-regulating genes. METHODS: Impulsive drive for immediate reward and delay aversion were measured in 459 male children and adolescents (328 ADHD and 131 unaffected siblings) with a laboratory choice task. The sample was genotyped for the 5HTT (SLC6A4) promoter serotonin-transporter-linked polymorphic region polymorphism and a …

DEFICIT HYPERACTIVITY DISORDERMedizinSocial Sciencesimpulsivity610 Medicine & healthCHILDRENSingle-nucleotide polymorphismGenomic disorders and inherited multi-system disorders Functional Neurogenomics [IGMD 3]attention-deficit/hyperactivity disorderImpulsivityCOMBINED-TYPE ADHDREACTION-TIME PERFORMANCEDevelopmental psychologyGenomic disorders and inherited multi-system disorders [IGMD 3]DOPAMINE03 medical and health sciences0302 clinical medicineDopaminemedicineAttention deficit hyperactivity disorderddc:610Medizinische Fakultät » Universitätsklinikum Essen » LVR-Klinikum Essen » Klinik für Psychiatrie Psychosomatik und Psychotherapie des Kindes- und JugendaltersAlleleBiological PsychiatrySerotonin transporter030304 developmental biologyDopamine transporterGeneticsMental Health [NCEBP 9]0303 health sciencesDELAY AVERSIONbiologyTRYPTOPHAN DEPLETIONASSOCIATION10058 Department of Child and Adolescent Psychiatrymedicine.diseasePOLYMORPHISM5-HTTLPR (SLC6A4)5-HTTLPRbiology.proteinCRITERION VALIDITYmedicine.symptomDAT1 (SLC6A3)Psychology2803 Biological PsychiatryFunctional Neurogenomics [DCN 2]030217 neurology & neurosurgerymedicine.drugBiological Psychiatry
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The overstated generational gap in online news use? A consolidated infrastructural perspective

2021

Recent research by Taneja et al. suggested that digital infrastructures diminish the generational gap in news use by counteracting preference structures. We expand on this seminal work by arguing that an infrastructural perspective requires overcoming limitations of highly aggregated web tracking data used in prior research. We analyze the individual browsing histories of two representative samples of German Internet users collected in 2012 ( N = 2970) and 2018 ( N = 2045) and find robust evidence for a smaller generational gap in online news use than commonly assumed. While short news website visits mostly demonstrated infrastructural factors, longer news use episodes were shaped more by …

FacebookNutzungmedia behaviorSociology and Political Sciencesocial mediaTwitterGenerationutilizationDigitale MedienFederal Republic of GermanyrepresentativityRepräsentativitätinfrastructureddc:070Digital infrastructures; generations; media repertoires; online news; preferences; social media; web trackingMedienverhaltenInteractive electronic MediaSoziale MedienMedienage-specific factorsnewsSocial mediaSociologyPositive economicspreferenceinteraktive elektronische Mediendigital mediaNews media journalism publishingOnline-MedienNachrichtenInternetStichprobeCommunicationInfrastrukturmediaPerspective (graphical)10800Präferenzonline mediasampleBundesrepublik DeutschlandPreferenceWeb trackingWork (electrical)altersspezifische FaktorenPublizistische Medien JournalismusVerlagswesenNew Media & Society
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