Search results for "AMA"

showing 10 items of 8558 documents

Sharing R&D investments in breakthrough technologies to control climate change

2017

This paper examines international cooperation on technological development as an alternative to international cooperation on GHG emission reductions. In order to analyze the scope of cooperation, a three-stage technology agreement formation game is solved. First, countries decide whether or not to sign up to the agreement. Then, in the second stage, the signatories (playing together) and the non-signatories (playing individually) select their investment in R&D. In this stage, it is assumed that the signatories not only coordinate their levels of R&D investment but also pool their R&D efforts to fully internalize the spillovers of their investment in innovation. Finally, in the third stage, …

021110 strategic defence & security studiesEconomics and EconometricsScope (project management)05 social sciencesControl (management)0211 other engineering and technologiesClimate change02 engineering and technologyInvestment (macroeconomics)MicroeconomicsOrder (exchange)Greenhouse gas0502 economics and businessDamagesEconomicsProduction (economics)050207 economicsIndustrial organizationOxford Economic Papers
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Microscopic Revelation of Charge-Trapping Sites in Polymeric Carbon Nitrides for Enhanced Photocatalytic Activity by Correlating with Chemical and El…

2019

The influences of chemical and electronic structures on the photophysical properties of polymeric carbon nitrides (PCNs) photocatalysts, which govern the microscopic mechanisms of the superior photocatalytic activity under visible-light irradiation, have been resolved in this work. Time-resolved photoluminescence and in situ electron paramagnetic resonance measurements indicate that the photoexcited electrons in the fractured PCNs swiftly transfer to the C2p-localized states where the trapped photoelectrons exhibit longer lifetime compared to those in the ordinary PCNs. Moreover, the structure deviation at the carbon (Cb) atoms around the bridging sites of heptazine ring units, where trappe…

021110 strategic defence & security studiesMaterials sciencePhotoluminescenceHeptazineHydrogen bond0211 other engineering and technologiesDFT calculation02 engineering and technologyElectronPhotoelectric effect021001 nanoscience & nanotechnologyPhotochemistrylaw.inventionpolymeric carbon nitridechemistry.chemical_compoundchemistrylawSSNMR spectroscopyPhotocatalysisGeneral Materials ScienceDensity functional theoryvisible-light-driven photocatalyst0210 nano-technologyElectron paramagnetic resonanceEPR spectroscopyACS Applied Materials & Interfaces
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Soils from an iron and steel scrap storage yard remediated with aided phytostabilization

2018

021110 strategic defence & security studiesWaste management0211 other engineering and technologiesSoil ScienceScrap02 engineering and technology010501 environmental sciencesDevelopment01 natural sciencesYardLand reclamationSoil waterEnvironmental ChemistryEnvironmental science0105 earth and related environmental sciencesGeneral Environmental ScienceLand Degradation & Development
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The Use of Wild Plants in the Palaeolithic and Neolithic of Northwestern Africa: Preliminary Results from the PALEOPLANT Project

2018

Carrión Marco Y., Morales J., Portillo M., Pérez-Jordà G., Peña-Chocarro L., Zapata L. (2018) The Use of Wild Plants in the Palaeolithic and Neolithic of Northwestern Africa: Preliminary Results from the PALEOPLANT Project. En: Mercuri A., D'Andrea A., Fornaciari R., Höhn A. (eds.) Plants and People in the African Past. Springer, Cham

0301 basic medicine010506 paleontologyPleistocenePhytolithsved/biology.organism_classification_rank.species01 natural sciencesSpherulites03 medical and health sciencesChamaeropsGlacial periodNeolithicCharcoalHolocene0105 earth and related environmental sciencesStipa tenacissimaPalaeolithicFood plantsbiologyEcologyved/biologyVegetation15. Life on landbiology.organism_classification030104 developmental biologyGeographyvisual_artCharcoalSeedsvisual_art.visual_art_mediumCalcitic microfossilsNorthwestern AfricaJuniperBasketry
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History and reality of the genus 'Homo' : what is it and why do we think so?

2017

Paleoanthropologists who worry about how nature is organized into species, and about what we should call them, are very often accused by their peers of «just arguing about names». This implies that basic taxonomy is a boring clerical operation that should be dispensed with as quickly as possible or even ignored, so that we can get to the really interesting questions about human evolution. Yet the reality is that we shall never understand the events of the intricate human evolutionary play if we cannot accurately identify the actors who participated in that drama. This article looks briefly at how our current supremely woolly concept of the genus Homo has come about, as background for urging…

0301 basic medicine03 medical and health sciences030104 developmental biologyMultidisciplinaryHistory and Philosophy of ScienceHuman evolutionBiologyHumanitiesDramaEpistemology
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Environmental aircraft noise aggravates oxidative DNA damage, granulocyte oxidative burst and nitrate resistance inOgg1–/–mice

2020

Background: Large epidemiological studies point towards a link between the incidence of arterial hypertension, ischaemic heart disease, metabolic disease and exposure to traffic noise, supporting t...

0301 basic medicine030102 biochemistry & molecular biologybusiness.industryEnvironmental stressorTraffic noiseGeneral MedicineGranulocytemedicine.diseasemedicine.disease_causeBiochemistryRespiratory burstOxidative dna damage03 medical and health scienceschemistry.chemical_compound030104 developmental biologymedicine.anatomical_structureNitratechemistryImmunologymedicineEndothelial dysfunctionbusinessOxidative stressFree Radical Research
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Investigation of Isoindolo[2,1-a] quinoxaline-6-imines as Topoisomerase I Inhibitors with Molecular Modeling Methods

2017

Background: Isoindolo[2,1-alpha] quinoxalines constitute an important class of compounds which demonstrated potent antiproliferative activity against different human tumor cell lines and topoisomerase I inhibitors. In particular, their water soluble imine or iminium salts recently synthesized showed potent growth inhibitory effect on NCI-60 tumor cell line panel and biological studies performed on the most active compounds demonstrated that they cause DNA damage via topoisomerase I poisoning. Objective: Herein, we investigate with molecular modeling methods, the common features responsible for topoisomerase I inhibition of the water-soluble isoindolo[2,1-alpha] quinoxalin-6-imines, by compa…

0301 basic medicine030103 biophysicsMolecular modelStereochemistryDNA damageAntineoplastic AgentsIsoindolesTopoisomerase-I InhibitorCrystallography X-RayaromatechinStructure-Activity Relationship03 medical and health scienceschemistry.chemical_compoundQuinoxalinetopotecanantiproliferativeCell Line TumorNeoplasmsQuinoxalinesquinoxalineDrug DiscoveryHumansCell Proliferationbiologypharmacophore modelTopoisomeraseIminiumGeneral MedicineSettore CHIM/08 - Chimica FarmaceuticaMolecular Docking SimulationTopoisomerase IindenoisoquinolineDNA Topoisomerases Type IchemistryDocking (molecular)dockingbiology.proteinMolecular MedicineTopoisomerase I; quinoxaline; antiproliferative; topotecan; aromatechin; indenoisoquinoline; docking; pharmacophore modelIminesTopoisomerase I InhibitorsPharmacophore
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Recent advances inγ-aminobutyric acid (GABA) properties in pulses: an overview

2017

Beans, peas, and lentils are all types of pulses that are extensively used as foods around the world due to their beneficial effects on human health including their low glycaemic index, cholesterol lowering effects, ability to decrease the risk of heart diseases and their protective effects against some cancers. These health benefits are a result of their components such as bioactive proteins, dietary fibre, slowly digested starches, minerals and vitamins, and bioactive compounds. Among these bioactive compounds, γ-aminobutyric acid (GABA), a non-proteinogenic amino acid with numerous reported health benefits (e.g. anti-diabetic and hypotensive effects, depression and anxiety reduction) is …

0301 basic medicine2. Zero hungerchemistry.chemical_classification030109 nutrition & dieteticsNutrition and DieteticsDecarboxylationGlutamate decarboxylase04 agricultural and veterinary sciencesBiology040401 food scienceAminobutyric acid3. Good healthAmino acidLactic acid03 medical and health scienceschemistry.chemical_compound0404 agricultural biotechnologyEnzymechemistryPhytochemicalBiochemistryFermentationAgronomy and Crop ScienceFood ScienceBiotechnologyJournal of the Science of Food and Agriculture
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Ceftolozane-Tazobactam Combination Therapy Compared to Ceftolozane-Tazobactam Monotherapy for the Treatment of Severe Infections: A Systematic Review…

2021

Ceftolozane-tazobactam (C/T) is a combination of an advanced-generation cephalosporin (ceftolozane) with a &beta

0301 basic medicine<i>pseudomonas aeruginosa</i>Biochemistrypseudomonas aeruginosasepsis0302 clinical medicinesystematic reviewceftolozanepolycyclic compoundsPharmacology (medical)030212 general & internal medicineGeneral Pharmacology Toxicology and Pharmaceuticsceftolozane-tazobactamAnti-infective agentInfectious DiseasesMeta-analysisCeftolozanemedicine.drugMicrobiology (medical)medicine.medical_specialtyCombination therapySepsiβ-lactamase inhibitors030106 microbiologyMicrobiologyTazobactamArticleSepsis03 medical and health sciencesmultidrug resistanceInternal medicinemedicineMeta-analysibacteremiabusiness.industryorganic chemicalslcsh:RM1-950Retrospective cohort studybiochemical phenomena metabolism and nutritionmedicine.diseasebacterial infections and mycosesinfectionmeta-analysisPneumonialcsh:Therapeutics. PharmacologyESBLESBLsBacteremiabacteriaanti-infective agentsbusiness
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Human skeletal muscle type 1 fibre distribution and response of stress-sensing proteins along the titin molecule after submaximal exhaustive exercise.

2017

Early responses of stress-sensing proteins, muscle LIM protein (MLP), ankyrin repeat proteins (Ankrd1/CARP and Ankrd2/Arpp) and muscle-specific RING finger proteins (MuRF1 and MuRF2), along the titin molecule were investigated in the present experiment after submaximal exhaustive exercise. Ten healthy men performed continuous drop jumping unilaterally on a sledge apparatus with a submaximal height until complete exhaustion. Five stress-sensing proteins were analysed by mRNA measurements from biopsies obtained immediately and 3 h after the exercise from exercised vastus lateralis muscle while control biopsies were obtained from non-exercised legs before the exercise. Decreased maximal jump h…

0301 basic medicineANKRD2AdultMalemedicine.medical_specialtyANKRD1HistologyAdolescentVastus lateralis musclePhysical ExertionMuscle Proteinslihaksetmedicine.disease_causetuki- ja liikuntaelimet03 medical and health sciencesYoung Adult0302 clinical medicineJumpingHsp27Internal medicinemedicinestress-sensing proteinsHumanstitinConnectinMolecular BiologyExerciseurheiluvammatbiologySkeletal muscleCell BiologyAnatomyhuman skeletal muscleMedical Laboratory Technology030104 developmental biologymedicine.anatomical_structureEndocrinologyMuscle Fibers Slow-Twitchbiology.proteinexercise induced muscle damageTitinAnkyrin repeat030217 neurology & neurosurgeryHistochemistry and cell biology
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