Search results for "AML"
showing 10 items of 184 documents
Design and Operation of a Windowless Gas Target Internal to a Solenoidal Magnet for Use with a Megawatt Electron Beam
2019
A windowless hydrogen gas target of nominal thickness $10^{19}$ cm$^{-2}$ is an essential component of the DarkLight experiment, which is designed to utilize the megawatt electron beam at an Energy Recovery Linac (ERL). The design of such a target is challenging because the pressure drops by many orders of magnitude between the central, high-density section of the target and the surrounding beamline, resulting in laminar, transitional, and finally molecular flow regimes. The target system was assembled and operated at Jefferson Lab's Low Energy Recirculator Facility (LERF) in 2016, and subsequently underwent several revisions and calibration tests at MIT Bates in 2017. The system at dynamic…
Forward production of charged pions with incident protons on nuclear targets at the CERN Proton Synchrotron
2009
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High-resolution spectroscopy of gaseous $^\mathrm{83m}$Kr conversion electrons with the KATRIN experiment
2020
In this work, we present the first spectroscopic measurements of conversion electrons originating from the decay of metastable gaseous $^\mathrm{83m}$Kr with the Karlsruhe Tritium Neutrino (KATRIN) experiment. The results obtained in this calibration measurement represent a major commissioning milestone for the upcoming direct neutrino mass measurement with KATRIN. The successful campaign demonstrates the functionalities of the full KATRIN beamline. The KATRIN main spectrometer's excellent energy resolution of ~ 1 eV made it possible to determine the narrow K-32 and L$_3$-32 conversion electron line widths with an unprecedented precision of ~ 1 %.
Optimising the Collinear Resonance Ionisation Spectroscopy (CRIS) experiment at CERN-ISOLDE
2020
© 2019 The CRIS experiment at CERN-ISOLDE is a dedicated laser spectroscopy setup for high-resolution hyperfine structure measurements of nuclear observables of exotic isotopes. Between 2015 and 2018 developments have been made to improve the background suppression, laser-atom overlap and automation of the beamline. Furthermore, a new ion source setup has been developed for offline studies. Here we present the latest technical developments and future perspectives for the experiment. ispartof: Nuclear Instruments & Methods In Physics Research Section B-Beam Interactions With Materials And Atoms vol:463 pages:384-389 ispartof: location:SWITZERLAND, CERN, Geneva status: published
Conversion electron spectroscopy at IGISOL
2012
Conversion elecron spectroscopy has been an important part of the nuclear spectrocopy research at the Department of Physics of the University of Jyv¨askyl¨a since the commissioning of the first cyclotron in the mid 1970s. At the IGISOL facility a specialiced conversion electron spectrometer ELLI was developed in the late 1980s. The first results with ELLI were obtained using the beams from the old MC-20 cyclotron to study newly discovered isotopes of refractory fission products. In the present K130 cyclotron laboratory ELLI has been utilized in many decay-spectroscopy experiments both neutron-deficient and neutron-rich side of the valley of stability. In the early 2000s the new JYFLTRAP ion…
Antiproton-Proton Cross Sections at Small Momenta
1990
Since the startup of LEAR in 1983 we have undertaken a series of measurements of antiproton-proton cross sections for annihilation (pp → mesons)1, charge-exchange reaction (pp → nn)2, and elastic scattering (pp → pp)3,4. We have focussed our efforts of the measurements on the beam momentum range between 160 and 600 MeV/c. Our detector is optimized to handle the antiproton beam at very small momenta5. The liquid hydrogen target is placed in the vacuum tank, and the vacuum is directly connected to the beam line. The incident beam is defined by thin scintillators also placed in the vacuum. With the apparatus of these unique designs we have explored the beam momentum region below 300 MeV/c with…
The energy loss system of the electron scattering facility at the Mainz 300 MeV linear accelerator
1978
Abstract An energy loss system was constructed for the electron scattering facility at the Mainz 300 MeV linear accelerator with the aim of improving the energy resolution and increasing the useful beam current. The main features of the design are: (1) the existing system (conventional mode) is kept in full operation, (2) for the energy loss mode, the electron beam is deflected vertically downwards and then returned to the original beam line by the dispersion matching system, consisting of three dipole magnets and one quadrupole magnet, (3) the dispersion of the beam on the target can be tuned to the dispersion of the spectrometer with the aid of the quadrupole magnet. With the installation…
Design of a second generation RFQ Ion Cooler and Buncher (RFQCB) for ISOLDE
2004
As a part of the ISOLDE Consolidation project, a new beam-cooling device will be incorporated into the High Resolution Separator (HRS) to improve the ion beam delivered to the experiments. The whole beam line at this point needs to be redesigned to accommodate the ion cooler and provide beam-matching. In this paper the status of the mechanical design, the optical design and the vacuum system of the device are presented.
Heavy ion and proton test site at JYFL-accelerator laboratory
1999
Abstract A radiation effects facility (RADEF) has been installed in the Accelerator Laboratory of the Department of Physics, University of Jyvaskyla (JYFL). The facility includes a special beam line dedicated to irradiation studies of semiconductor components and devices. It consists of a vacuum chamber including component movement apparatus and the necessary diagnostic equipment required for beam quality and intensity analysis. Construction of the station began in the summer of 1996, and in August 1997 the suitability of the station for space applications was evaluated. In this paper we introduce the accelerator laboratory along with the test station and its properties. We also describe th…
Evolving patterns of care and outcomes in relapsed/refractory FLT3 mutated acute myeloid leukemia adult patients.
2021
We have analyzed treatment patterns and outcomes of relapsed/refractory(R/R) FLT3mut AML adult patients registered in our institutional data base between 1998 and 2018. Overall, 147 patients were evaluable: 34 from 1998 to 2009, 113 from 2010 to 2018. Salvage treatments were intensive chemotherapy ( n = 25, 74%), and supportive care ( n = 9, 26%) in the 1998-2009 period, and intensive chemotherapy ( n = 63, 56%), hypomethylating agent ( n = 7, 6%), low-dose cytarabine-based ( n = 8, 7%), clinical trial ( n = 16, 14%) and supportive care ( n = 19, 17%) in the 2010-2018 period. Complete remission (CR) or with incomplete recovery (CRi) rate was 44%, 49% among patients treated intensively (vs 3…