Search results for "AMP"

Ionising radiation and lens opacities in interventional physicians: results of a German pilot study

2019

We assessed the feasibility of an epidemiological study on the risk of radiation-related lens opacities among interventional physicians in Germany. In a regional multi-centre pilot study associated with a European project, we tested the recruitment strategy, a European questionnaire on work history for the latter dosimetry calculation and the endpoint assessment. 263 interventional physicians and 129 non-exposed colleagues were invited. Questionnaires assessed eligibility criteria, risk factors for cataract, and work history relating to occupational exposure to ionising radiation, including details on type and amount of procedures performed, radiation sources, and use of protective equipmen…

Radiation effects on light scattering and cataract formation in the lenses of interventional radiologist and cardiologists

2014

Purpose There is little information about exposure to dosages below 500 mSv. This pilot study aimed at investigating the effects of low dose radiation on lens transparency in occupationally exposed interventional cardiologists and radiologists. Methods Physicians who have performed fluoroscopically guided procedures for at least 5 years were recruited in the areas of Cologne-Bonn and Rhine-Main together with their non-exposed colleagues. A questionnaire has been developed to estimate occupational exposure. Exclusion criteria comprised corticosteroid treatment, radiotherapy, chemotherapy and glaucoma. Changes in lens transparency and cataract formation were determined by slit lamp microscopy…

Model-specific effects of bumetanide on epileptiform activity in the in-vitro intact hippocampus of the newborn mouse.

2007

The immature brain has a higher susceptibility to develop seizures, which often respond poorly to classical pharmacological treatment. It has been recently suggested that bumetanide, which blocks Na(+)-dependent K(+)-Cl(-)-cotransporter isoform 1 (NKCC1) and thus attenuates depolarizing GABAergic responses, could soothe epileptiform activity in immature nervous systems. To evaluate whether bumetanide consistently attenuates epileptiform activity, we investigated the effect of 10 microM bumetanide in five different in-vitro epilepsy models using field potential recordings in the CA3 region of intact mouse hippocampal preparations at postnatal day 4-7. Bumetanide reduced amplitude and frequen…

Patterns of rapid weight loss in elite sambo athletes

2021

Abstract Background Rapid weight loss (RWL) is commonly practiced in combat sports. Both magnitude and methods used to induce RWL are largely similar among combat sports, but currently, there is no data on RWL methodology used by sambo athletes. Therefore, the aim of this study was to determine RWL procedures sambo athletes apply to lose weight rapidly. Methods The sample consisted of 199 participants, of which 132 males and 67 females who participated in the World Sambo Championship 2020 held in Novi Sad, Serbia. Each participant received RWL questionnaire that was available in multiple languages, and every participant was instructed how to fill it out. Results Almost 87% of sambo particip…

Iliac-femoral stent-graft infection after hybrid procedure redo: Case report

2021

Introduction Stent-graft infection in peripheral arteries is rare and potentially dangerous. The use of hybrid procedures, in complicated patients previously treated, involves an increase of infective risk especially in no collaborative patients. Presentation of case We report a case of rare stent-graft infection in a patient treated for a Rutherford IV Multiple Peripheral Arterial Disease (MPAD) involving the right iliac-femoral axis with stenosis on deep femoral artery due to a previously stenting procedure for Superficial Femoral artery (SFA) stenosis. The first simultaneous hybrid intervention consisted of an endovascular iliac stent-graft placement and a surgical common femoral patch a…

2019

We investigated the ability of energy expenditure, movement sensing, and muscle activity to discriminate sedentary and non-sedentary activities in children. Thirty-five 7-11-year-old children participated in the study. Simultaneous assessment of oxygen uptake (VO2), triaxial accelerometry, and thigh muscle electromyography (EMG) were performed during eight different sedentary and non-sedentary activities including lying down, sitting-, standing-, and walking-related activities, which were performed in a random order. Mean values of VO2, accelerometry, and EMG from the concurrent 2 min epochs during each activity were computed. Resting energy expenditure (REE) was measured during 30 min supi…

Methamphetamine abuse and meth mouth in Europe

2014

With easy chemical synthesis from its precursor, methamphetamine (MA) is now widespread in many countries. The abuse of methamphetamine is associated with several negative effects on health, because MA is a neurotoxin and a dangerous central nervous system stimulant. It changes levels of neurotransmitters in the brain, releasing dopamine and inhibiting nor epinephrine uptake which increases sympathetic nervous system activity and can lead to cardiac arrhythmia, hypertension and tachypnea. The consequences of MA abuse are clearly manifested in oral diseases (like “meth mouth”) which is characterised by extensive caries, teeth grinding with ensuing dental wear and trismus. The present review …

Experiences from cross-cultural collaboration in health campaigns in Tanzania: a qualitative study

2021

Abstract Background Health campaigns are an important aspect of preventive health work. They can aim to improve health literacy in rural areas where residents lack access to health information and knowledge, and to improve both local and global health through cross-cultural collaboration. In Tanga District, Tanzania, exchange students and local youths participate together with Tanga International Competence Centre (TICC) to plan and accomplish health campaigns in local communities. The aim of this study was to explore the participants’ experiences with the cross-cultural collaboration in the planning and delivery of TICC’s health campaigns. Methods This study used a focused ethnographic app…

Calcium inhibits ovarian steroidogenesis in the blowfly Phormia regina.

2002

1479-6805 0022-0795; Calcium is frequently involved in the stimulation of steroidogenesis in gonads and endocrine glands, generally in association with cAMP. However, our present observations show that it has the opposite effect in the ovary of the blowfly Phormia regina. Our in vitro experiments first showed that extracellular calcium does not play a role during the stimulation of steroidogenesis in fly ovaries; indeed steroidogenesis was activated in vitro as efficiently in a medium with or without calcium, either by pharmacological compounds mimicking cAMP signaling or by active brain extracts. When calcium was experimentally introduced into biosynthetic cells by ionophores or liberated …

Water maze performance, exploratory activity, inhibitory avoidance and hippocampal plasticity in aged superior and inferior learners

2002

In 28- to 30-month-old rats, in vitro short-term and long-term potentiation (STP and LTP) were measured in area CA1 of the hippocampus in seven superior and seven inferior learners, that were selected from a pool of 40 rats based on water maze escape performance over a period of 9 days. The aim was to examine whether levels of STP and LTP could account for group differences in learning of water maze escape, spatial preference and wall (thigmotaxis)-avoidance and in short-term retention of an inhibitory avoidance task. There was no significant group difference in open-field exploration, i.e. the number of rearings. In contrast to expectation, the superior and inferior learners did not differ…