Search results for "ANCA"
showing 10 items of 419 documents
Notas taxonómicas y distributivas sobre <em>Serapias lingua</em> subsp. <em>tunetana</em> (Orchidaceae), una rara espècie end…
2019
Serapias lingua subsp. tunetana, una rara orquídea endémica con área de distribución restringida en Túnez, al norte de Túnez, ha sido redescubierta lejos de su localidad tipo después de 22 años. Desde su primer hallazgo en 1996 y su descripción publicada en 2005, la subespecie no se había encontrado nuevamente y se presume que se extinguió o fue identificada erróneamente. En este trabajo se proporciona una descripción detallada de la subespecie que justifica una enmienda a su descripción, y se aporta asimismo un mapa de distribución y varias fotografías. Se listan las principales afinidades de la subsp. tunetana con los táxones más estrechamente relacionados dentro del grupo de S. lingua qu…
A Pan-Cancer Approach to Predict Responsiveness to Immune Checkpoint Inhibitors by Machine Learning
2019
Immunotherapy by using immune checkpoint inhibitors (ICI) has dramatically improved the treatment options in various cancers, increasing survival rates for treated patients. Nevertheless, there are heterogeneous response rates to ICI among different cancer types, and even in the context of patients affected by a specific cancer. Thus, it becomes crucial to identify factors that predict the response to immunotherapeutic approaches. A comprehensive investigation of the mutational and immunological aspects of the tumor can be useful to obtain a robust prediction. By performing a pan-cancer analysis on gene expression data from the Cancer Genome Atlas (TCGA, 8055 cases and 29 cancer types), we …
A rare association of chronic lymphocytic leukemia with c-ANCA-positive Wegener’s granulomatosis: a case report
2016
Background Wegener’s granulomatosis is a systemic vasculitis of the small- and medium-sized vessels, produced by the action of ANCA, which involves the respiratory tract, kidneys, and eyes, with a potential for lethal evolution in the first year after diagnosis. Its association with chronic lymphocytic leukemia is rarely described in the literature, and it may be difficult to diagnose and to treat this association. Case presentation We present the case of a 73-year-old Caucasian patient, a rare case in which Wegener’s granulomatosis is associated in a patient with chronic lymphocytic leukemia, who is admitted in the Infectious Disease Department for fever, diplopia, headache, purulent and h…
Increased ischemic stroke, acute coronary artery disease and mortality in patients with granulomatosis with polyangiitis and microscopic polyangiitis.
2018
International audience; Objective: The aim of our study was to assess major cardiovascular event incidence, predictors, and mortality in ANCA-associated vasculitis (AAV).Methods: We conducted a retrospective cohort study of all GPA or MPA, according to Chapel Hill Consensus Conference classification criteria, diagnosed between 1981 and 2015. Major cardiovascular event was defined as acute coronary artery disease, or ischemic stroke, or peripheral vascular disease requiring a revascularization procedure. We calculated the comparative morbidity/mortality figure (CMF) and we used Cox proportional hazards regression models to assess the risk of coronary artery disease, ischemic stroke associate…
Hypertrophic pachymeningitis and cerebral venous thrombosis in myeloperoxidase-ANCA associated vasculitis
2019
Hypertrophic pachymeningitis (HP) is a circumscribed inflammatory process that thickens meninges with fibrous adhesions. Among the causes of HP, vasculitis and autoimmune disease should be considered; myeloperoxidase (MPO)-antinuclear cytoplasmatic antibodies (ANCA)-positivity can be the only
If you can defend your own point of view, you're good : Norms of voice construction in student writing on an international Master's programme
2019
Abstract This ethnographically oriented study followed the writing experiences of four students on an international masters programme in Finland. Gathering a range of data, the study set out to examine what counts as good writing on a programme with a very diverse student body in which English is used as a lingua franca. Both teachers and students emphasised the importance of arguing one's ‘own point of view’ in academic writing, and teachers often formed impressions of students on the basis of their texts, drawing attention particularly to their use of metadiscourse markers (e.g., self-mentions, attitude markers and hedges). The present article therefore combines a quantitative analysis of…
Polish Adolescents’ Perceptions of English and Their Desire to Learn It
2016
In the process of foreign language learning the way in which students perceive the language may have a strong facilitative impact on their language acquisition process, especially when this perception is positive (Despagne, 2010). Unfortunately, it has not yet been clearly established whether the relationship between perceptions and foreign language achievement can be explained by the moderating power of the student’s desire to learn the foreign language. For the purpose of this paper it is hypothesized that the learner’s perception of the foreign language is strongly related to the desire to learn it, leading to higher achievement in cases of positive perception. In order to corroborate th…
Les armes contre la terreur
2004
Mujer y representación política institucional en la Comunidad Valenciana. 1977-1995. Diputadas, ministras y cargos institucionales
2014
“Mujer y representación política institucional en la Comunidad Valenciana. 1977-1995. Diputadas, ministras y cargos institucionales” es la primera parte de un trabajo de documentación para un capítulo de “La democracia en la Comunidad Valenciana. Partidos, elites políticas, elecciones y programas políticos”. “Mujer, poder político y democracia paritaria”. Se recoge el papel de la mujer en la vida política de la Comunidad Valenciana en la democracia actual, desde 1977. Es documentación sin elaborar, pero que aporta datos de la presencia de la mujer en las instituciones, partidos y sindicatos. Cuando este completa será una parte de la investigación referida, y de la que ya hay dos publicacion…
Los determinantes del endeudamiento y del spread de crédito y liquidez de los bonos de gobiernos subsoberanos europeos
2014
La descentralización política y administrativa en Europa desde el fin de la segunda guerra mundial ha sido muy intensa, lo que ha propiciado la asunción de competencias por parte de las regiones, vinculadas en general con el estado de bienestar, y que los marcos de relación con las administraciones centrales tienen unos rasgos muy comunes cuya fortaleza depende del país de que se trate. Países de naturaleza federal como Alemania, Austria o Bélgica que junto a España que también tiene un nivel elevado de competencias descentralizadas en contraposición a Francia e Italia. En casi todos los marcos institucionales analizados, contienen reglas fiscales internas que permiten controlar el gasto pú…