Search results for "ANCA"
showing 10 items of 419 documents
Museums as Disseminators of Niche Knowledge
2019
Accessibility has been facing several challenges within Audiovisual Translation Studies and has also gained great opportunities for its establishment as a methodologically and theoretically well-founded discipline. Audiovisual translation modes have achieved a crucial role in the transmission of what scholarly studies have discussed in relation to media accessibility as a set of services and practices providing access to audiovisual media content for persons with sensory impairment. Today accessibility has become a concept involving more and more universality, since it is extensively contributing to the dissemination of audiovisual and visual products about issues on minorities, and also ad…
Information Dynamics Analysis: A new approach based on Sparse Identification of Linear Parametric Models*
2020
The framework of information dynamics allows to quantify different aspects of the statistical structure of multivariate processes reflecting the temporal dynamics of a complex network. The information transfer from one process to another can be quantified through Transfer Entropy, and under the assumption of joint Gaussian variables it is strictly related to the concept of Granger Causality (GC). According to the most recent developments in the field, the computation of GC entails representing the processes through a Vector Autoregressive (VAR) model and a state space (SS) model typically identified by means of the Ordinary Least Squares (OLS). In this work, we propose a new identification …
Neutrophil extracellular traps mediate transfer of cytoplasmic neutrophil antigens to myeloid dendritic cells toward ANCA induction and associated au…
2012
AbstractAntineutrophil cytoplasmic antibodies (ANCAs) target proteins normally retained within neutrophils, indicating that cell death is involved in the autoimmunity process. Still, ANCA pathogenesis remains obscure. ANCAs activate neutrophils inducing their respiratory burst and a peculiar form of cell death, named NETosis, characterized by formation of neutrophil extracellular traps (NETs), decondensed chromatin threads decorated with cytoplasmic proteins endorsed with antimicrobial activity. NETs have been consistently detected in ANCA-associated small-vessel vasculitis, and this association prompted us to test whether the peculiar structure of NET favors neutrophil proteins uploading i…
Le contrôle des risques bancaires. Une approche historique des enjeux et des résistances lors du changement de référentiel comptable de 2005.
2023
Ce chapitre analyse pourquoi et comment l'adoption des normes comptables internationales dans leur forme initiale aurait conduit à une remise en cause de la pratique de la macro-couverture utilisée par les grandes banques françaises pour gérer leur risque de taux. Plus largement il étudie en quoi cette remise en cause était susceptible d'avoir une incidence sur leur modèle économique et leur politique de crédit ainsi que les résistances, notamment politiques, qui ont été à l'œuvre
Identification of a genetic signature enriching for response to ibrutinib in relapsed/refractory follicular lymphoma in the DAWN phase 2 trial.
2021
Abstract Background The single‐arm DAWN trial (NCT01779791) of ibrutinib monotherapy in patients with relapsed/refractory follicular lymphoma (FL) showed an overall response rate (ORR) of 20.9% and a median response duration of 19.4 months. This biomarker analysis of the DAWN dataset sought to determine genetic classifiers for prediction of response to ibrutinib treatment. Methods Whole exome sequencing was performed on baseline tumor samples. Potential germline variants were excluded; a custom set of 1216 cancer‐related genes was examined. Responder‐ versus nonresponder‐associated variants were identified using Fisher's exact test. Classifiers with increasing numbers of genes were created …
"Al final de mi vida no sé qué es ser valenciano". Fragmentos de una entrevista inédita con José Vidal-Beneyto en su muerte
2010
Osman, metafora onomastica nell'opera di Carlo Francavilla
2018
L'articolo verte su Osman come metafora onomastica nell'opera di Carlo Francavilla.
Traditional Chinese herbal medicine at the forefront battle against COVID-19: Clinical experience and scientific basis.
2020
Abstract Background Throughout the 5000-year history of China, more than 300 epidemics were recorded. Traditional Chinese herbal medicine (TCM) has been used effectively to combat each of these epidemics’ infections, and saved many lives. To date, there are hundreds of herbal TCM formulae developed for the purpose of prevention and treatment during epidemic infections. When COVID-19 ravaged the Wuhan district in China in early January 2020, without a deep understanding about the nature of COVID-19, patients admitted to the TCM Hospital in Wuhan were immediately treated with TCM and reported later with >90% efficacy. Approach We conducted conduct a systematic survey of various TCM herbal pre…
‘The Germanic Background’
2017
Il seicentesco palazzo vescovile di Santa Lucia del Mela (Messina)
2013
The Bishop's Palace in Santa Lucia del Mela (Messina) was built from 1607, commissioned by Don Simone Rao Grimaldi, as prestigious seat for his successors. The riliefs, which are stored in the Archivo General de Simancas, all together with the evaluation of the building and the deed of gift to Filippo III, and the documentary findings due to local scholars, offer the change to consider the constructive issue of a building still less well-known and his "mysterious" architect.