Search results for "ANESTHESIA"
showing 10 items of 2277 documents
Remote photoplethysmography system for unsupervised monitoring regional anesthesia effectiveness
2017
Determining the level of regional anesthesia (RA) is vitally important to both an anesthesiologist and surgeon, also knowing the RA level can protect the patient and reduce the time of surgery. Normally to detect the level of RA, usually a simple subjective (sensitivity test) and complicated quantitative methods (thermography, neuromyography, etc.) are used, but there is not yet a standardized method for objective RA detection and evaluation. In this study, the advanced remote photoplethysmography imaging (rPPG) system for unsupervised monitoring of human palm RA is demonstrated. The rPPG system comprises compact video camera with green optical filter, surgical lamp as a light source and a …
Breakthrough Cancer Pain: Ten Commandments
2016
The term "breakthrough cancer pain" (BTcP) was introduced about 25 years ago. Peaks of pain intensity reported in patients with cancer had been invariably examined in the past years, providing relevant information for a better knowledge of this phenomenon and its treatment. The aim of this critical review was to provide the golden rules, namely, the 10 commandments, for a correct diagnostic pathway of BTcP and a consequent personalized pharmacological treatment. These are as follows: 1) assessment of background analgesia, 2) drugs used for background analgesia, 3) BTcP is a frequent phenomenon, 4) characteristics of BTcP, 5) diagnosis of BTcP, 6) continuous assessment, 7) tailored pharmacol…
Influence of Propofol on Neuronal Damage and Apoptotic Factors after Incomplete Cerebral Ischemia and Reperfusion in Rats
2004
Background Propofol reduces neuronal damage from cerebral ischemia when investigated for less than 8 postischemic days. This study investigates the long-term effects of propofol on neuronal damage and apoptosis-related proteins after cerebral ischemia and reperfusion. Methods Male Sprague-Dawley rats were randomly assigned as follows: group 1 (n = 32, control): fentanyl and nitrous oxide-oxygen; group 2 (n = 32, propofol): propofol and oxygen-air. Ischemia (45 min) was induced by carotid artery occlusion and hemorrhagic hypotension. Pericranial temperature and arterial blood gases were maintained constant. After 1, 3, 7, and 28 postischemic days, brains were removed, frozen, and sliced. Hi…
A Dose-Dependent Improvement in Exercise Tolerance in Patients With Stable Angina Treated With Mildronate: A Clinical Trial “MILSS I”
2011
Objective. To assess the efficacy of various doses of Mildronate in combination with standard therapy for the exercise tolerance of patients with stable angina pectoris. The primary efficacy variable was the change in exercise time in bicycle ergometry from the baseline to 12 weeks of treatment. The secondary endpoints were the changes in maximum achieved load and time to the onset of angina from the baseline to week 12. Material and Methods. A total of 512 patients with chronic coronary heart disease who had ischemia as the limiting factor in the exercise test from 72 study centers in 4 countries were enrolled in this prospective, randomized, double-blind, placebo controlled phase 2 study.…
Long-term placement of continuous popliteal nerve block catheter for management of a wounded patient in a combat field environment: a case report.
2019
Costantino Fontana,1 Monica Rocco,2 Luigi Vetrugno,3 Elena Bignami41Anesthesia and Intensive Care Unit, Sapienza University of Rome, Rome, Italy; 2Intensive Care Unit and Anesthesia, Ospedale S. Andrea Rome, Rome, Italy; 3Anesthesia and Intensive Care Clinic, University-Hospital of Udine, Udine, Italy; 4Intensive Care Unit and Anestehsia, Università degli Studi di Parma, Parma, ItalyCorrespondence: Costantino FontanaAnesthesia and Intensive Care Unit, Sapienza University of Rome, Policlinico Militare di Roma, Piazza Celimontana n. 50, Roma 00184, ItalyEmail cosfontana@gmail.comAbstract: Continuous peripheral nerve block is a relevant part of multimodal treatment of postoperative pain…
Clinical pain evaluation with intraoral vibration device during local anesthetic injections
2014
Objectives: To evaluate the clinical pain during local anesthetic injection using such intra-oral device. Study Design: A comparative split-mouth clinical study to evaluate clinical pain was conducted among the subjects who required bilateral local anesthetic intra-oral injections. Results: A total of 99 subjects participated in the study out of which 39 were female. A total of 256 local anesthetic injections were administered to all the subjects with at least one pair of similar local anesthetic injections. Comparison of mean VAS score for anticipated pain in without vibration group was significantly higher in all types of nerve blocks when compared to that of with vibration. Similarly, th…
Risk factors and determinants of intraoperative hyperlactatemia in major non-cardiac surgery.
2021
Ventilation through a ‘straw’: the final answer in a totally closed upper airway?
2015
Changes of Hemodynamic Parameters, Pulmonary Gas Exchange, and Extravascular Lung Water During Esophageal Cancer Surgery
1988
Esophagectomy is often connected to postoperative pulmonary complications with a high mortality rate [1, 3,4]. From 1980 to 1985 we treated 19 patients after esophagectomy in our intensive care unit. Nine patients (47%) died of pulmonary complications. From the literature [3] and from our own observations we came to the conclusion that the first pulmonary changes start during the operative procedure.