Search results for "ANTIOXIDANTS"

showing 7 items of 827 documents

LYCOPENE AND PROSTATE CANCER: AN OVERVIEW

2018

Prostate cancer is one of the most common cancers in the world. Its pathogenesis is multifactorial and is linked to risk factors such as age, diet, cigarette smoking, family history and the onset of oxidative stress. In recent times, therefore, we are investigating the use of antioxidants as a primary and tertuary prevention of prostate cancer. Numerous studies in the literature focused on lycopene, a molecule belonging to the family of carotenoids that is commonly foud in tomatoes and products derived from it. The literature analyzed in the last two years shows how lycopene inhibits different mecchanism linked to carcinogenesis and tumor progression. However, there are still many points to…

prostate cancer antioxidants lycopene
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Phenolic Profiles, Antioxidant and Anti-Inflammatory Activities of Hydrodistillation Wastewaters from Five Lamiaceae Species

2022

Distillation is the most widely used method to obtain an essential oil from plant material. The biomass used in the process is returned as a solid residue together with variable amounts of water rich in water-soluble compounds, which currently are not addressed to any further application. The scope of this work was to evaluate the phytochemical composition of wastewaters coming from hydrodistillation (DWWs) of five aromatic plants belonging to the Lamiaceae family, and to assess their in vitro antioxidant and anti-inflammatory activities. The phenolic profiles of the DWWs were determined by HPLC-DAD and HPLC-ESI/MS. Free radical scavenging ability, oxygen radical antioxidant capacity and su…

radical scavengingrosmarinic aciddistillation wastes; phenolic profile; rosmarinic acid; intestinal inflammation; anti-inflammatory; radical scavenging; antioxidantantioxidantLamiaceaePlant ExtractsSettore AGR/13 - Chimica AgrariaPhytochemicalsOrganic ChemistryAnti-Inflammatory AgentsWaterPharmaceutical ScienceWastewaterphenolic profileAntioxidantsSettore AGR/02 - Agronomia E Coltivazioni ErbaceeAnalytical ChemistryPhenolsChemistry (miscellaneous)intestinal inflammationDrug DiscoveryMolecular Medicinedistillation wastePhysical and Theoretical Chemistryanti-inflammatoryMolecules
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Antioxidant Therapies and Oxidative Stress in Friedreich´s Ataxia: The Right Path or Just a Diversion?

2020

Friedreich's ataxia is the commonest autosomal recessive ataxia among population of European descent. Despite the huge advances performed in the last decades, a cure still remains elusive. One of the most studied hallmarks of the disease is the increased production of oxidative stress markers in patients and models. This feature has been the motivation to develop treatments that aim to counteract such boost of free radicals and to enhance the production of antioxidant defenses. In this work, we present and critically review those 'antioxidant' drugs that went beyond the disease's models and were approved for its application in clinical trials. The evaluation of these trials highlights some …

reactive oxygen speciesFriedreich’s ataxia; clinical trials; oxidative stress; antioxidant therapies; reactive oxygenspecies; scavengers; antioxidant response; mitochondrial metabolism; ferroptosisclinical trialsmitochondrial metabolismantioxidant responseEstrès oxidatiulcsh:RM1-950Friedreich’s ataxiaReviewFriedreich´s ataxia590 Tiere (Zoologie)Antioxidantsferroptosisscavengerslcsh:Therapeutics. Pharmacology570 Biowissenschaften Biologieddc:590oxidative stressantioxidant therapiesddc:570Antioxidants
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Antioxidant Effects of Dietary Supplements on Adult COVID-19 Patients: Why Do We Not Also Use Them in Children?

2022

Respiratory tract infections (RTIs) are very common in children, especially in the first five years of life, and several viruses, such as the influenza virus, Respiratory Syncytial Virus, and Rhinovirus, are triggers for symptoms that usually affect the upper airways. It has been known that during respiratory viral infections, a condition of oxidative stress (OS) occurs, and many studies have suggested the potential use of antioxidants as complementary components in prophylaxis and/or therapy of respiratory viral infections. Preliminary data have demonstrated that antioxidants may also interfere with the new coronavirus 2’s entry and replication in human cells, and that they have a role in …

respiratory viral infectionsoxidative stretherapyantioxidantPhysiologySARS-CoV-2prophylaxiClinical BiochemistryCOVID-19Cell BiologyBiochemistryantioxidantschildrenoxidative stressCOVID-19 SARS-CoV-2 antioxidants children oxidative stress prophylaxis respiratory viral infections therapyprophylaxisrespiratory viral infectionMolecular BiologyAntioxidants (Basel, Switzerland)
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Serenoa repens, lycopene and selenium versus tamsulosin for the treatment of LUTS/BPH. An Italian multicenter double-blinded randomized study between…

2014

serenoa repensMaleProstatic HyperplasiaAntioxidantsSettore MED/24 - UrologiaSeleniumDouble-Blind MethodDrug TherapyLower Urinary Tract SymptomsSerenoa80 and overHumansBPH; LUTS; lycopene; phytotherapy; selenium; serenoa repens; tamsulosin; Aged; Aged 80 and over; Antioxidants; Carotenoids; Double-Blind Method; Drug Therapy Combination; Humans; Italy; Lower Urinary Tract Symptoms; Male; Middle Aged; Phytotherapy; Prostatic Hyperplasia; Quality of Life; Selenium; Serenoa; Sulfonamides; Treatment Outcome; Urodynamics; Urological AgentsAgedSulfonamidesLUTSphytotherapyMiddle AgedlycopeneCarotenoidsBPH LUTS lycopene phytotherapy selenium serenoa repens tamsulosinUrodynamicsTreatment OutcomeItalyBPHtamsulosinCombinationQuality of LifeUrological Agentsserenoa repens; lycopene; selenium; tamsulosin; LUTS; BPH; phytotherapy
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Evaluation of the Behavior of Phenolic Compounds and Steviol Glycosides of Sonicated Strawberry Juice Sweetened with Stevia (Stevia rebaudiana Berton…

2019

In this study, the influence of stevia addition and sonication processing parameters on the phenolic content and profile as well as the steviol glycosides of strawberry juice-based samples was investigated. For this purpose, three matrices&mdash

sonicationSonicationgreen stevia powder ; strawberry juice ; antioxidant compounds ; steviol glycosides ; sonicationPharmaceutical ScienceSteviol01 natural sciencesFragariaArticleAntioxidantsAnalytical Chemistrylcsh:QD241-441chemistry.chemical_compound0404 agricultural biotechnologylcsh:Organic chemistryantioxidant compoundsGlucosidesPhenolsDrug DiscoveryFood scienceSteviosidePhysical and Theoretical Chemistrysteviol glycosidesstrawberry juiceChromatography High Pressure Liquidchemistry.chemical_classificationFlavonoidsbiologyPlant Extracts010401 analytical chemistryOrganic ChemistryGlycoside04 agricultural and veterinary sciencesSweetnessgreen stevia powderbiology.organism_classification040401 food scienceStevia0104 chemical sciencesStevia rebaudianachemistryChemistry (miscellaneous)Molecular MedicineKaempferolDiterpenes KauraneMolecules
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In-Depth Characterization of Bioactive Extracts from Posidonia oceanica Waste Biomass

2019

© 2019 by the authors.

ved/biology.organism_classification_rank.speciesPhytochemicalsPharmaceutical ScienceBiomassMicrobiologiaantioxidant capacity7. Clean energy01 natural sciencesEcologia marinaAntioxidantsFoodborne Diseaseschemistry.chemical_compoundMicevalorisationAnti-Infective AgentsDrug DiscoveryFood scienceAntifungal activityBiomasslcsh:QH301-705.5Pharmacology Toxicology and Pharmaceutics (miscellaneous)Caliciviridae InfectionsPlant Proteinschemistry.chemical_classificationFeline calicivirusAlismatalesbiologyultrasound04 agricultural and veterinary sciences040401 food scienceantiviralLipids6. Clean waterAntioxidant capacityMicrobiologia marinaPosidonia oceanicaMitosporic FungiValorisationValorisationMicrobial Sensitivity TestsPolysaccharideArticle0404 agricultural biotechnologyPhenolsPolysaccharidesUltrasoundAnimalsHumansAntiviralHot water extractionEthanolEthanol010405 organic chemistryved/biologyPlant Extractsantifungal activityNorovirusWaterbiology.organism_classification0104 chemical sciencesEcologiaHot water extractionRAW 264.7 Cellslcsh:Biology (General)chemistryCatsSolventsAntiviralesQuímica Analíticahot water extractionMurine norovirusCalicivirus FelineMarine Drugs
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