Search results for "APAR"

showing 10 items of 848 documents

Laparoscopic surgery for isolated inguinal node relapse of high grade serous ovarian cancer using a bipolar combination instrument

2020

Abstract Objective To demonstrate step-by-step minimally invasive surgical technique for dissection of isolated inguinal node relapse of high grade serous ovarian cancer. Methods A 54-year-old woman, BRCA1 +, underwent to open abdominal total hysterectomy, bilateral salpingo-oophorectomy, total omentectomy, pelvic and aortic lymphadenectomy with zero residual disease, for high grade serous ovarian carcinoma FIGO stage IIB. After surgery, patient underwent platinum-based chemotherapy for six cycles and follow-up examinations every 3 months for the first year and biannual for the second one. Abdominal TC-PET scan after 18 months revealed a right distal iliac external/inguinal nodal relapse (S…

AdultLaparoscopic surgerymedicine.medical_specialtyendocrine system diseasesmedicine.medical_treatmentInguinal CanalOvarian carcinomamedicineHumansMinimally Invasive Surgical ProceduresLaparoscopyOvarian NeoplasmsHysterectomymedicine.diagnostic_testbusiness.industryPrognosismedicine.diseasefemale genital diseases and pregnancy complicationsCystadenocarcinoma SerousSurgerySerous fluidDeep inguinal ringmedicine.anatomical_structureOncologyCancer Inguinal Laparoscopy Ovarian Relapse SurgeryFemaleLaparoscopySurgeryLymphadenectomyNeoplasm Recurrence LocalOvarian cancerbusinessSurgical Oncology
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Is ‘anxiety sensitivity’ predictive of postoperative nausea and vomiting?

2019

BACKGROUND Postoperative nausea and vomiting (PONV) is an extremely distressing side effect for patients. Despite PONV prophylaxis guided by well established scoring systems, the incidence of PONV is still high. OBJECTIVE The aim of the current study was to investigate the predictive value of anxiety sensitivity as an additional independent risk factor for PONV in patients with an increased risk of PONV. DESIGN A noninterventional, observational study. SETTING A tertiary care university hospital. PATIENTS Patients with an increased risk of PONV (i.e. female, nonsmoking) undergoing elective surgery (general, gynaecological, urological, musculoskeletal or neurosurgical) under general anaesthe…

AdultLaparoscopic surgerymedicine.medical_specialtymedicine.medical_treatmentAnesthesia GeneralAnxietyRisk AssessmentPredictive Value of TestsRisk FactorsInternal medicineHumansMedicineGeneral anaesthesiaProspective StudiesRisk factorElective surgeryAgedPsychological Testsbusiness.industryIncidenceAge FactorsOdds ratioMiddle AgedPrognosisAnesthesiology and Pain MedicineElective Surgical ProceduresPostoperative Nausea and VomitingAnxiety sensitivityAntiemeticsFeasibility StudiesFemaleObservational studymedicine.symptombusinessPostoperative nausea and vomitingEuropean Journal of Anaesthesiology
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Laparoscopic-ultrasonographic combined technique for the creation of a neovagina in Mayer-Rokitansky-Kuster-Hauser syndrome

1996

Objective To create a neovagina using a combined laparoscopic and ultrasonographic technique in Mayer-Rokitansky-Kuster-Hauser syndrome by modification of Vecchietti's operation. Design Case report. Setting Division of Physiopathology of Reproduction, University of Palermo, Palermo, Italy. Main Outcome Measure(s) The advancement of the needle from the pseudohymen, through the vesicorectal space using a triple contrast ultrasonographic technique. Result(s) The ultrasonographic scanning guides the accurate transit from external genitalia to the peritoneal cavity. Conclusion(s) This original approach allowed a safe and rapid creation of a neovagina in a case of Mayer-Rokitansky-Kuster-Hauser s…

AdultLaparoscopic surgerymedicine.medical_specialtymedicine.medical_treatmentEndoscopic surgeryCombined techniquemedicineHumansAbnormalities MultipleMayer-Rokitansky-Kuster-Hauser SyndromePeritoneal CavityUltrasonographymedicine.diagnostic_testbusiness.industryUterusOutcome measuresObstetrics and GynecologyGenitalia FemaleSyndromeSurgeryEndoscopyReproductive MedicineExternal genitaliaVaginaFemaleLaparoscopyOperative laparoscopybusinessFertility and Sterility
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How to select early-stage cervical cancer patients still suitable for laparoscopic radical hysterectomy: a propensity-matched study

2020

Background: Recently, it was reported that minimally invasive surgery (MIS) has a negative impact on early-stage cervical cancer (ECC) patient survival. At the same time, advantages of MIS regarding quality of life and low rate of intra- and postoperative complications are well known. Therefore, it is essential to select patients who may benefit from MIS without worsening their oncologic outcomes. The aim of this study is to investigate which pathological factors could guide surgeons’ choice about the best approach in ECC. Patients and Methods: Patients with 2009 FIGO stage from IA1 with lymphovascular space invasion (LVSI) to IB1/IIA1 treated by open or laparoscopic surgery were judged eli…

AdultLaparoscopic surgerymedicine.medical_specialtymedicine.medical_treatmentlaparoscopyUterine Cervical NeoplasmsHysterectomyDisease-Free Survivalopen surgeryYoung Adult03 medical and health sciences0302 clinical medicineSurgical oncologymedicineHumansMinimally Invasive Surgical ProceduresRadical HysterectomyPropensity ScoreLaparoscopyGrading (tumors)minimally invasive surgeryAgedNeoplasm StagingRetrospective StudiesAged 80 and overCervical cancermedicine.diagnostic_testbusiness.industryParametrialCervical cancer; laparoscopy; minimally invasive surgery; open surgery; radical hysterectomy; tumor diameterHazard ratioMiddle Agedmedicine.diseaseSurgerySurvival RateTreatment OutcomeSettore MED/40 - GINECOLOGIA E OSTETRICIAItalyOncology030220 oncology & carcinogenesisradical hysterectomyCervical cancerFemale030211 gastroenterology & hepatologySurgerytumor diameterbusiness
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Prospective Randomized Comparison of Minilaparoscopy and Percutaneous Liver Biopsy

2007

Liver cirrhosis represents an advanced stage of hepatic fibrosis characterized by distortion of organ architecture and formation of regenerative nodules. Retrospective series reported percutaneous liver biopsy to miss cirrhosis in about 30%. The aim of this study was to prospectively compare diagnostic sensitivity regarding the detection of cirrhosis and the complication rates of percutaneous versus minilaparoscopic liver biopsy in chronic liver disease.Eight hundred fifty-seven patients were randomized to percutaneous (415) or to minilaparoscopic liver biopsy (442). Macroscopic liver evaluation was documented as normal, fibrosis, or cirrhosis. Liver specimens were assessed blindly accordin…

AdultLiver CirrhosisMalemedicine.medical_specialtyCirrhosisBiopsyDiagnosis DifferentialBiopsymedicineHumansProspective StudiesProspective cohort studyLaparoscopymedicine.diagnostic_testbusiness.industryGastroenterologyMiddle AgedPrognosismedicine.diseaseSurgeryLiverLiver biopsyChronic DiseaseFemaleLaparoscopyHistopathologyRadiologyGastrointestinal HemorrhageHepatic fibrosisComplicationbusinessFollow-Up StudiesJournal of Clinical Gastroenterology
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Diagnosis of Liver Cirrhosis

2005

Background/goals Liver cirrhosis, the final stage of chronic liver disease, is characterized by an unfavorable prognosis and an increased risk of hepatocellular carcinoma and also requires an appropriate management. Laparoscopy, the gold standard in the diagnosis of cirrhosis, is hampered by its invasiveness. Therefore, a noninvasive method for diagnosing liver cirrhosis would be of great benefit. Study A consecutive series of 100 patients, sent to our gastroenterological unit for diagnostic laparoscopy, underwent a standardized ultrasonographic examination prior to laparoscopy. Results Conventional ultrasonographic examination revealed a sensitivity of 55% and a specificity of 86% in the d…

AdultLiver CirrhosisMalemedicine.medical_specialtyCirrhosisChronic liver diseaseSensitivity and SpecificityGastroenterologyInternal medicineHumansMedicineStage (cooking)LaparoscopyAgedUltrasonographyAged 80 and overChi-Square Distributionmedicine.diagnostic_testbusiness.industryUltrasoundGastroenterologyGold standard (test)Middle Agedmedicine.diseaseEndoscopyHepatocellular carcinomaFemaleLaparoscopyRadiologybusinessJournal of Clinical Gastroenterology
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Laparoscopic treatment for esophageal achalasia: experience at a single center

2013

Background. Achalasia is a not frequent esophageal disorder cha- racterized by the absence of esophageal peristalsis and incomplete re- laxation of the lower esophageal sphincter (LES). Its cause is unknown. The aim of treatment is to improve the symptoms. We report the results of the treatment of this condition achieved in one center. Patients and methods. We conducted a retrospective study of pa- tients with esophageal achalasia. In the period 2010-2012 we observed 64 patients, of whom 19 were referred for medical treatment. Three of Introduction Achalasia is a not frequent esophageal motor disor- der that affects both the body of the esophagus and the lower esophageal sphincter (LES). It…

AdultMaleAdolescentMiddle AgedClinical PracticeEsophageal AchalasiaSettore MED/18 - Chirurgia GeneraleYoung Adultlaparoscopy - Heller myotomy - intraoperative manometryHumansFemaleLaparoscopyAgedRetrospective Studies
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Implication of the Examining Pathologist to Meet the Oncologic Standard of Lymph Node Count after Laparoscopic Lymphadenectomy

2010

<i>Objective:</i> The lymph node number as benchmark in oncologic operations depends on the patient’s anatomy, surgeon’s skill and pathologist’s accuracy. The influence of the pathologist is barely evaluated. <i>Methods:</i> A retrospective analysis of lymph node numbers after 700 laparoscopic lymphadenectomies in correlation to the examining pathologists was done. Three surgeons from the same department performed all operations at 2 campi, where 2 separate pathology institutions exist. Lymph node specimens were assigned randomly to any of the 62 involved pathologists. <i>Results:</i> The mean number of lymph nodes was equal for all surgeons. Lymph node s…

AdultMaleCancer Researchmedicine.medical_specialtyPathologyAdolescentPelviPathology Surgicalmedicine.medical_treatmentGynecologic oncologyMedical OncologyPelvisYoung AdultRetrospective StudieGynecologic oncology; Laparoscopic lymphadenectomy; Lymph node numberNeoplasmsHumansMedicineLaparoscopyLaparoscopic lymphadenectomyLymph nodeAgedNeoplasm StagingRetrospective StudiesAged 80 and overLaparoscopic lymphadenectomymedicine.diagnostic_testbusiness.industryGeneral surgeryLymph NodeGeneral MedicineMiddle AgedSettore MED/40 - Ginecologia E Ostetriciadigestive system diseasesEndoscopyGynecologic oncologysurgical procedures operativemedicine.anatomical_structureOncologyLymph node numberPractice Guidelines as TopicNeoplasmLymph Node ExcisionFemaleLaparoscopyLymphadenectomyLymph NodesbusinessHumanOncology
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Automatic numerical-spatial association in synaesthesia: An fMRI investigation

2016

A horizontal mental number line (MNL) is used to describe how quantities are represented across space. In humans, the neural correlates associated with such a representation are found in different areas of the posterior parietal cortex, especially, the intraparietal sulcus (IPS). In a phenomenon known as number-space synaesthesia, individuals visualise numbers in specific spatial locations. The experience of a MNL for number-space synaesthetes is explicit, idiosyncratic, and highly stable over time. It remains an open question whether the mechanisms underlying numerical-spatial association are shared by synaesthetes and nonsynaesthetes. We address the neural correlates of number-space assoc…

AdultMaleCognitive NeuroscienceAutomaticityPosterior parietal cortexExperimental and Cognitive PsychologyIntraparietal sulcusNeuropsychological TestsBrain mapping050105 experimental psychologyDevelopmental psychologyAssociationPerceptual Disorders03 medical and health sciencesBehavioral Neuroscience0302 clinical medicineSupramarginal gyrusReaction TimemedicineHumans0501 psychology and cognitive sciencesAssociation (psychology)Brain MappingNeural correlates of consciousnessmedicine.diagnostic_test05 social sciencesBrainMathematical ConceptsMagnetic Resonance ImagingPattern Recognition VisualSpace PerceptionFunctional magnetic resonance imagingPsychologySynesthesia030217 neurology & neurosurgeryCognitive psychologyNeuropsychologia
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Double-Balloon Enteroscopy: Preliminary Experience in Patients with Obscure Gastrointestinal Bleeding or Chronic Abdominal Pain

2003

Background and Study Aims: Even in the era of capsule endoscopy, diseases of the small bowel are sometimes difficult to diagnose, and endoscopic treatment is not possible without surgical laparotomy. The new method of carrying out enteroscopy using a double-balloon technique allows not only diagnostic but also therapeutic endoscopic interventions for lesions in the small bowel. Preliminary experience with this new method is reported here. Patients and Methods: Between the end of March 2003 and August 2003, eight patients (four women, four men; mean age 59 ± 23 years, range 20 - 90) with chronic gastrointestinal bleeding or abdominal pain, or both, underwent enteroscopy using the double-bal…

AdultMaleEnteroscopymedicine.medical_specialtyAbdominal painGastrointestinal Diseasesmedicine.medical_treatmentEndoscopy GastrointestinalAngiodysplasialaw.inventionCrohn DiseaseCapsule endoscopylawLaparotomyDouble-balloon enteroscopymedicineHumansAngiodysplasiaAgedAged 80 and overmedicine.diagnostic_testbusiness.industryGastroenterologyMiddle Agedmedicine.diseaseAbdominal PainEndoscopySurgeryTherapeutic endoscopyFemalemedicine.symptomGastrointestinal HemorrhagebusinessEndoscopy
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