Search results for "APR"
showing 10 items of 2648 documents
Exposure to Perfluoroalkyl Substances and Metabolic Outcomes in Pregnant Women: Evidence from the Spanish INMA Birth Cohorts
2017
BACKGROUND: Exposure to perfluoroalkyl substances (PFASs) may increase risk for metabolic diseases; however, epidemiologic evidence is lacking at the present time. Pregnancy is a period of enhanced tissue plasticity for the fetus and the mother and may be a critical window of PFAS exposure susceptibility. OBJECTIVE: We evaluated the associations between PFAS exposures and metabolic outcomes in pregnant women. METHODS: We analyzed 1,240 pregnant women from the Spanish INMA [Environment and Childhood Project (INfancia y Medio Ambiente)] birth cohort study (recruitment period: 2003-2008) with measured first pregnancy trimester plasma concentrations of four PFASs (in nanograms/milliliter). We u…
Interleukin-25-mediated resistance against intestinal trematodes does not depend on the generation of Th2 responses
2020
AbstractInterleukin-25 (IL-25) is recognized as the most relevant initiator of protective Th2 responses in intestinal helminth infections. It is well known that IL-25 induces resistance against several species of intestinal helminths, including the trematode Echinostoma caproni. E. caproni has been extensively used as an experimental model to study the factors determining the resistance to intestinal infections. Herein, we assessed the role of IL-25 in the generation of resistance in mice to E. caproni infections. ICR mice are permissive hosts for E. caproni in which chronic infections are developed in relation to the lack of IL-25 production in response to primary infection and the consequ…
HCV NS3 sequencing as a reliable and clinically useful tool for the assessment of genotype and resistance mutations for clinical samples with differe…
2016
OBJECTIVES: This study aims to evaluate the reliability and clinical utility of NS3 sequencing in hepatitis C virus (HCV) 1-infected patients who were candidates to start a PI-containing regimen. METHODS: NS3 protease sequencing was performed by in-house-developed HCV-1 subtype-specific protocols. Phylogenetic analysis was used to test sequencing reliability and concordance with previous genotype/subtype assignment by commercial genotyping assays. RESULTS: Five hundred and sixty-seven HCV plasma samples with quantifiable HCV-RNA from 326 HCV-infected patients were collected between 2011 and 2014. Overall, the success rate of NS3 sequencing was 88.9%. The success rate between the two subtype…
Researching Identity and L2 Pragmatics in Digital Stories: A Relational Account.
2020
This study explores college EFL learners' construction of identity through the analysis of their pragmatic choices in digital stories, in which they narrated their relationship with another person they had helped in the past. More specifically, such choices were examined following Relational Dialectics Theory in learners' enactments of "connection" with and "autonomy" from this person. A specific view of identity in language education, the notion of "relational work" in (im)politeness research, and a social semiotic framework were also employed in data analysis. Learners' pragmatic choices ranged from the selection of the topic of their narratives according to types of social bonds, to the …
Translating Teacher Funds of Identity into Curricular Proposals for the EFL Classroom: A Model for Student-Teacher Innovation and Professional Develo…
2019
This article describes the progress and findings of a research project, organized in the context of a university Masters course in Teaching English as a Foreign Language (TEFL), which aimed at translating the student-teachers' (STs) funds of identity into worthwhile curricular proposals for the English as a Foreign Language (EFL) subject. The first part of the research involved 38 STs in three workshops through which they became aware of their own funds of identity, expanded their own teacher identity, and finally designed curricular proposals that incorporated their funds of identity as valuable pedagogical resources. The second part of the research took place during the two-month practicu…
PNA
2007
Resumen basado en el de la publicación Se presentan algunos de los resultados más relevantes de un estudio sobre la problemática de la enseñanza y el aprendizaje de los números complejos. Para ello se presenta un cuestionario en el que se ha planteado a un grupo de 19 alumnos de primero de la Licenciatura de Matemáticas una serie de problemas relacionados con la materia. Este estudio está dirigido a recabar información para sustentar sugerencias de intervención en las pautas educativas en relación con esta temática. Se concluye que los alumnos presentan dificultades e inconsistencias al responder a las tareas del cuestionario y se cuestiona la educación recibida por los alumnos en lo que se…
The Role of Perceived Relevance and Attention in Teachers’ Attitude and Intention to Use Educational Video Games
2017
Educational video games (EVGs) are becoming a trending topic in education as a new teaching methodology which can help teachers to increase students’ attention and engagement during the learning process. Nevertheless, despite an increasing academic interest in EVGs little research has been devoted to delve into teacher’s beliefs affecting their attitude towards EVGs and how these beliefs also affect their intention to use EVGs in their courses. Using Keller’s ARCS model as a theoretical framework, the role of perceived relevance and attention in teachers’ attitude and intention to use EVGs is analyzed. To do so a research model is tested using a sample of 312 Higher Education teachers via s…
Diseño de tareas telecolaborativas para el aprendizaje de idiomas con cuentos del mundo
2018
Este artículo se centra en el diseño de tareas de telecolaboración para el desarrollo de competencias lingüísticas, literarias, interculturales y digitales, teniendo en cuenta las diferentes acciones llevadas a cabo antes y durante el proyecto de cara a garantizar el éxito del mismo. La propuesta, realizada en el marco del proyecto iTECLA, conjuga la telecolaboración con la redacción e intercambio de cuentos que reflejan valores culturales de los respectivos países de origen de los participantes. El proyecto implica la realización de una serie de tareas por parte de cada estudiante, mediante un proceso guiado de análisis y reflexión basado en métodos de trabajo telecolaborativo en línea en …
Glikozes transportieru un slāpekļa oksīda produkcijas izmaiņas cukura diabēta komplikāciju patoģenēzē un to farmakoloģiskās korekcijas iespējas
2014
Elektroniskā versija nesatur pielikumus
A Tool to Assess Architectural Education from the Sustainable Development Perspective and the Students' Viewpoint
2021
[EN] Architectural education plays a fundamental role in achieving sustainable development by training future professionals who can contribute to sustainability through their practice. Nevertheless, to ensure the introduction of sustainable development in the education of future architects, it is fundamental to understand what is being done and what could be improved. Despite this, a big gap has been detected in the assessment of architectural education in Spain and worldwide. Thus, a close-ended questionnaire for students has been designed based on the outcomes from a literature review, exploratory interviews with specialists, and the qualitative analysis of two schools of architecture. Ad…