Search results for "APT"
showing 10 items of 5479 documents
Enkephalin-containing interneurons are specialized to innervate other interneurons in the hippocampal CA1 region of the rat and guinea-pig
1998
Enkephalins are known to have a profound effect on hippocampal inhibition, but the possible endogenous source of these neuropeptides, and their relationship to inhibitory interneurons is still to be identified. In the present study we analysed the morphological characteristics of met-enkephalin-immunoreactive cells in the CA1 region of the rat and guinea-pig hippocampus, their coexistence with other neuronal markers and their target selectivity at the light and electron microscopic levels. Several interneurons in all subfields of the hippocampus were found to be immunoreactive for met-enkephalin. In the guinea-pig, fibres arising from immunoreactive interneurons were seen to form a plexus …
Nicotinic receptor agonists as neuroprotective/neurotrophic drugs. Progress in molecular mechanisms
2007
In the present work we reviewed recent advances concerning neuroprotective/neurotrophic effects of acute or chronic nicotine exposure, and the signalling pathways mediating these effects, including mechanisms implicated in nicotine addiction and nAChR desensitization. Experimental and clinical data largely indicate long-lasting effects of nicotine and nicotinic agonists that imply a neuroprotective/neurotrophic role of nAChR activation, involving mainly alpha 7 and alpha 4 beta 2 nAChR subtypes, as evidenced using selective nAChR agonists. Compounds interacting with neuronal nAChRs have the potential to be neuroprotective and treatment with nAChR agonists elicits long-lasting neurotrophic e…
High-precision measurement of the mass difference between 102Pd and 102Ru
2019
The Q-value for the neutrinoless double electron capture on 102Pd, Qϵϵ(102Pd), is determined as the atomic mass difference between 102Pd and 102Ru. A precise measurement of the Qϵϵ(102Pd) at the SHIPTRAP Penning trap showed a more than 10σ deviation to the adopted Atomic Mass Evaluation (AME) value. The reliability of the SHIPTRAP measurement was challenged because the AME value was based on numerous experiments including β and electron capture decays and very precise (n, γ) data, all agreeing with each other. To solve the discrepancy, the Qϵϵ(102Pd) has now been determined with the JYFLTRAP Penning trap at the IGISOL facility in the Accelerator Laboratory of the University of Jyväskylä. Th…
Population Properties of Compact Objects from the Second LIGO-Virgo Gravitational-Wave Transient Catalog
2021
Abbott, R., et al. (LIGO and Virgo Collaboration)
Haptotropism in a Nickel Complex with a Neutral, π‐Bridging cyclo‐P4 Ligand Analogous to Cyclobutadiene
2022
The reaction of ( 1 )Ni(η 2 -cod), 2 , incorporating a chelating bis( N -heterocyclic carbene) 1 , with P 4 in pentane yielded the dinuclear complex [( 2 )Ni] 2 (μ 2 ,η 2 :η 2 -P 4 ), 3 , formally featuring a cyclobutadiene-like, neutral, rectangular, π-bridging P 4 -ring. In toluene, the butterfly-shaped complex [( 1 )Ni] 2 (μ 2 ,η 2 :η 2 -P 2 ), 4 , with a formally neutral P 2 -unit was obtained from 2 and either P 4 or 3 . Computational studies showed that a low energy barrier haptotropic rearrangement involving two isomers of the μ 2 ,η 2 :η 2 -P 4 coordination mode and a low energy μ 2 ,η 4 :η 4 -P 4 coordination mode, as previously predicted for related nickel cyclobutadiene complexes…
Computational Structures and SAPT Interaction Energies of HXeSH···H2Y (Y=O or S) Complexes
2018
Ab initio calculations of the structures, vibrational spectra and supermolecular and symmetry-adapted perturbation theory (SAPT) interaction energies of the HXeOH and HXeSH complexes with H2O and H2S molecules are presented. Two minima already reported in the literature were reproduced and ten new ones were found together with some transition states. All complexes show blue shift in Xe&ndash
Ķīmiskais arodvides risks farmaceitiem un farmaceitu asistentiem, kas gatavo zāles atvērta tipa aptiekā
2020
Šī darba mērķis bija pētīt ķīmisko arodvides risku farmaceitiem/farmaceitu asistentiem, kas gatavo zāles atvērta tipa aptiekā, izmantojot dažādas ķīmiskā riska novērtēšanas metodes. Rezultāti rāda, ka tiem, kas gatavo zāles, biežāk novēro ādas simptomātiku (p=0,042), ķīmiskais risks pētītajā aptiekā novērtēts ar III pakāpi – ciešams, bet 64,4% no zāļu gatavošanā izmantotajām vielām pētītajā aptiekā mēneša ietvaros uzskatāmas par bīstamām. Iegūtie dati varētu liecināt, par vielu iedarbību uz darbiniekiem, vedinot domāt, ka zāļu gatavošana atvērta tipa aptiekā varētu būt darbiniekiem kaitīgs un bīstams darbs, taču ir vajadzīgi turpmāki pētījumi, lai skaidrotu darbā iegūtās iespējamās cēloņsak…
Psihoemocionālie darba vides riska faktori un to mazināšanas iespējas PII "Kamenīte" darbiniekiem
2020
Kvalifikācijas darba autore: Līga Kalneniece Kvalifikācijas darba vadītāja: Mg.Sc. Kristīne Andža Kvalifikācijas darba tēma: “Psihoemocionālie darba vides riska faktori un to mazināšanas iespējas PII “Kamenīte” darbiniekiem”. Kvalifikācijas darba mērķis: Pētīt psihoemocionālo risku ietekmi darbiniekiem, šo risku mazināšana. Darbinieku anketēšana, secinājumi, priekšlikumu sniegšana risku mazināšanai. Kvalifikācijas darba teorētiskā daļa: Psihoemocionālie riski, risku ietekme, to mazināšana (preventīvie pasākumi). Veikt secinājumus, sniegt priekšlikumus. Kvalifikācijas darba analītiskā daļa: Vispārīgi apstāvoši darba vides riski pirmskolās, iespējamās arodslimības. Darba vides risku novērtēša…
Parietal Cortex Connectivity as a Marker of Shift in Spatial Attention Following Continuous Theta Burst Stimulation
2021
Non-invasive brain stimulation is a useful tool to probe brain function and provide therapeutic treatments in disease. When applied to the right posterior parietal cortex (PPC) of healthy participants, it is possible to temporarily shift spatial attention and mimic symptoms of spatial neglect. However, the field of brain stimulation is plagued by issues of high response variability. The aim of this study was to investigate baseline functional connectivity as a predictor of response to an inhibitory brain stimulation paradigm applied to the right PPC. In fourteen healthy adults (9 female, aged 24.8 ± 4.0 years) we applied continuous theta burst stimulation (cTBS) to suppress activity in the …
The beta-delayed proton and gamma decay of 27P for nuclear astrophysics
2013
The creation site of 26Al is still under debate. It is thought to be produced in hydrogen burning and in explosive helium burning in novae and supernovae, and possibly also in the H-burning in outer shells of red giant stars. Also, the reactions for its creation or destruction are not completely known. When 26Al is created in novae, the reaction chain is: 24Mg(p, γ) 25Al(β +ν) 25Mg(p, γ) 26Al, but this chain can be by-passed by another chain, 25Al(p, γ) 26Si(p, γ) 27P and it can also be destroyed directly. The reaction 26mAl(p, γ) 27Si∗ is another avenue to bypass the production of 26Al and it is dominated by resonant capture. We find and study these resonances by an indirect method, throug…