Search results for "ARDS"
showing 10 items of 1705 documents
Procedimento estratégico em três estágios de seleção de variáveis para a obtenção de resultados equilibrados na pesquisa em saúde pública
2018
Multidisciplinary research in public health is approached using methods from many scientific disciplines. One of the main characteristics of this type of research is dealing with large data sets. Classic statistical variable selection methods, known as “screen and clean”, and used in a single-step, select the variables with greater explanatory weight in the model. These methods, commonly used in public health research, may induce masking and multicollinearity, excluding relevant variables for the experts in each discipline and skewing the result. Some specific techniques are used to solve this problem, such as penalized regressions and Bayesian statistics, they offer more balanced results a…
Afferent and efferent projections of the dorsal anterior thalamic nuclei in the lizard Podarcis hispanica (Sauria, Lacertidae).
2002
The aim of this study was to investigate the afferent and efferent connections of the anterior thalamic nuclei in the lizard Podarcis hispanica. To identify potential sources of sensory inputs and to determine the fine organization of the projections of these thalamic nuclei to the telencephalon, we injected the sensitive tracer biotinylated dextran amine (BDA) into different nuclei of the anterior dorsal thalamus. We also injected BDA into several telencephalic areas in order to corroborate the results of thalamic injections. Our results show that the anterior thalamic nuclei receive projections from multiple areas and nuclei distributed throughout most of the brain, from rhombencephalon t…
Effects of a Mediterranean Eating Plan on the Need for Glucose-Lowering Medications in Participants With Type 2 Diabetes: A Subgroup Analysis of the …
2019
OBJECTIVE: To examine the effects of two Mediterranean eating plans (Med-EatPlans) versus a low-fat eating plan on the need for glucose-lowering medications. RESEARCH DESIGN AND METHODS: From the Prevención con Dieta Mediterránea (PREDIMED) trial, we selected 3,230 participants with type 2 diabetes at baseline. These participants were randomly assigned to one of three eating plans: Med-EatPlan supplemented with extra-virgin olive oil (EVOO), Med-EatPlan supplemented with mixed nuts, or a low-fat eating plan (control). In a subgroup (15%), the allocation was done in small clusters instead of using individual randomization, and the clustering effect was taken into account in the statistical a…
Insulin resistance and atrial fibrillation (from the Framingham Heart Study)
2011
Diabetes mellitus and obesity are increasing in prevalence and are associated with an elevated risk of atrial fibrillation (AF). Given the aging of the United States population, AF is projected to concomitantly increase in prevalence in the upcoming decades. Both diabetes and obesity are associated with insulin resistance. Whether insulin resistance is an intermediate step for the development of AF is uncertain. We hypothesized that insulin resistance is associated with an increased risk of incident AF. We examined the association of insulin resistance with incident AF using multivariate Cox proportional hazards regression analysis adjusting for the established AF risk factors (i.e., age, g…
Inscriptions mineures du sanctuaire des Bolards à Nuits-Saint-Georges (France, Côte-d’Or) : l’exemple des graffiti sur enduits peints
2018
International audience
Dépôts de bronzes et relations visuelles autour du Camp du Château à Salins-les-Bains (Jura, France) à la fin du Bronze moyen et au début du Bronze f…
2017
Systematic field surveys have been carried out in the surroundings of the Camp du Château near Salins-les-Bains for several years. These investigations led to the discovery of forty-odd hoards dating mainly from the end of the Middle Bronze Age and the beginning of the Late Bronze Age. The good accuracy of their localization allows us to study how they were integrated into the landscape. Their positioning suggests that the choice of location favored topographical criteria. We are interested in the question of intervisibility between the place of hoarding and the remarkable points of the natural and social landscape, especially the hill-forts. The results of GIS analysis show the constitutio…
Reliability of the representation of a distribution: a case-study on Middle Bronze Age metal finds in the Seine valley
2013
International audience; Controlling the uncertainties and the documentary lacks of an archaeological corpus should be the priority to interpret correctly the data distribution. The conception of a reliability map in order to estimate the quality of the inventory, the creation of a representation map so as to highlight the over- and under-representations and finally their combination, the confidence map, are efficient tools to spot out the zones concerning which there is a risk for a defective interpretation. We propose here, an application on a case-study of Middle Bronze Age metal hoards and isolated finds, for which the only really determining factor is the possibility for discoveries sin…
Influence of the Richardson number on EM force driven flow structures in square-shaped crucible
2014
Abstract This study is devoted to the experimental investigation of the turbulent melt motion in a square crucible where the flow is created by Lorentz forces generated by an external AC magnetic field. As a strong vertical thermal gradient is present in melt during a directional solidification process, a stratification effect takes place and motion in the vertical direction is damped by buoyancy forces. Such a situation arises if density of fluid layers decreases with height. Experimental velocity and temperature measurements are conducted. Transient effects, like collapse of stratification, are observed experimentally. The significance of stratification in the directional solidification m…
Fonction et usage de la lettre de rémission chez les ducs de Bourgogne à la fin du Moyen Âge
2015
The letter of remission is a codified document given by the prince, stopping any procedure against people. It forgives the criminal and brings him back his good fama. It allows the historian to wonder about the forgiveness procedure that was established first by the monarchy, then by several territorial princes notably the dukes of Burgundy. The conditions in which these documents were produced at the end of the Middle Ages, their multiple copies and the copies that were made several decades after the initial pardon and that are conserved in the chartrier of the dukes of Burgundy in the Archives Départementales de Côte d’Or invites us to analyze the different practices through time, first b…
Heterogeneous expression of cell adhesion molecules by endothelial cells in ARDS
2002
ARDS (acute respiratory distress syndrome) can be associated with septic shock and multiple organ failure caused by an uncontrolled systemic inflammatory response to Gram-negative bacterial infection. While in animal models the key role of the endothelial adhesion molecules ICAM-1, E-selectin, and VCAM in ARDS has been extensively studied, there are scarcely any corresponding pathomorphological studies of human lung tissue. Hence, little is known about whether there is a comparable, or even heterogeneous, expression pattern of these molecules in the human pulmonary vasculature. This study was therefore undertaken to investigate the immunohistochemical expression of the constitutively expres…