Search results for "ARTICLES"
showing 10 items of 9626 documents
Small RNA‐binding protein RapZ mediates cell envelope precursor sensing and signaling in Escherichia coli
2019
Abstract The RNA‐binding protein RapZ cooperates with small RNAs (sRNAs) GlmY and GlmZ to regulate the glmS mRNA in Escherichia coli. Enzyme GlmS synthesizes glucosamine‐6‐phosphate (GlcN6P), initiating cell envelope biosynthesis. GlmZ activates glmS expression by base‐pairing. When GlcN6P is ample, GlmZ is bound by RapZ and degraded through ribonuclease recruitment. Upon GlcN6P depletion, the decoy sRNA GlmY accumulates through a previously unknown mechanism and sequesters RapZ, suppressing GlmZ decay. This circuit ensures GlcN6P homeostasis and thereby envelope integrity. In this work, we identify RapZ as GlcN6P receptor. GlcN6P‐free RapZ stimulates phosphorylation of the two‐component sy…
Radiation Hardness Assurance Through System-Level Testing: Risk Acceptance, Facility Requirements, Test Methodology, and Data Exploitation
2021
International audience; Functional verification schemes at a level different from component-level testing are emerging as a cost-effective tool for those space systems for which the risk associated with a lower level of assurance can be accepted. Despite the promising potential, system-level radiation testing can be applied to the functional verification of systems under restricted intrinsic boundaries. Most of them are related to the use of hadrons as opposed to heavy ions. Hadrons are preferred for the irradiation of any bulky system, in general, because of their deeper penetration capabilities. General guidelines about the test preparation and procedure for a high-level radiation test ar…
Sense of coherence and burnout in nursing home workers during the COVID‐19 pandemic in Spain
2021
Abstract Care staff in nursing homes work in a challenging environment, and the COVID‐19 pandemic has exacerbated those challenges in an unprecedented way. On the other hand, the sense of coherence (SOC) is a competence that could help these professionals perceive the situation as understandable, manageable and meaningful. This study aims to analyse the extent to which potential risk and protective factors against burnout have affected nursing home workers during the COVID‐19 pandemic and to assess the contribution of these factors to their burnout. Three hundred forty professionals who worked in nursing homes in Spain completed a survey and reported on their sociodemographic characteristic…
Kinetic Properties of Cl−Uptake Mediated by Na+-Dependent K+-2Cl−Cotransport in Immature Rat Neocortical Neurons
2007
GABA, the main inhibitory neurotransmitter in the adult nervous system, evokes depolarizing membrane responses in immature neurons, which are crucial for the generation of early network activity. Although it is well accepted that depolarizing GABA actions are caused by an elevated intracellular Cl−concentration ([Cl−]i), the mechanisms of Cl−accumulation in immature neurons are still a matter of debate. Using patch-clamp, microfluorimetric, immunohistochemical, and molecular biological approaches, we studied the mechanism of Cl−uptake in Cajal-Retzius (CR) cells of immature [postnatal day 0 (P0) to P3] rat neocortex. Gramicidin-perforated patch-clamp and 6-methoxy-N-ethylquinolinium-microfl…
Sphinx measurements of the 2009 solar minimum x-ray emission
2012
The SphinX X-ray spectrophotometer on the CORONAS-PHOTON spacecraft measured soft X-ray emission in the 1-15 keV energy range during the deep solar minimum of 2009 with a sensitivity much greater than GOES. Several intervals are identified when the X-ray flux was exceptionally low, and the flux and solar X-ray luminosity are estimated. Spectral fits to the emission at these times give temperatures of 1.7-1.9 MK and emission measures between 4 x 10^47 cm^-3 and 1.1 x 10^48 cm^-3. Comparing SphinX emission with that from the Hinode X-ray Telescope, we deduce that most of the emission is from general coronal structures rather than confined features like bright points. For one of 27 intervals o…
Search for Gamma-Ray Emission from the Sun during Solar Minimum with the ARGO-YBJ Experiment
2019
The hadronic interaction of cosmic rays with solar atmosphere can produce high energy gamma-rays. The gamma-ray luminosity is correlated both with the flux of primary cosmic rays and the intensity of the solar magnetic field. The gamma-rays below 200 GeV have been observed by Fermi without any evident energy cutoff. The bright gamma-ray flux above 100 GeV has been detected only during solar minimum. The only available data in the TeV range come from the HAWC observations, however, outside the solar minimum. The ARGO-YBJ data set has been used to search for sub-TeV/TeV gamma-rays from the Sun during the solar minimum from 2008 to 2010, the same time period covered by the Fermi data. A suitab…
Gravitational Lensing of Supernova Neutrinos
2006
The black hole at the center of the galaxy is a powerful lens for supernova neutrinos. In the very special circumstance of a supernova near the extended line of sight from Earth to the galactic center, lensing could dramatically enhance the neutrino flux at Earth and stretch the neutrino pulse.
Resonant origin for density fluctuations deep within the Sun: helioseismology and magneto-gravity waves
2003
We analyze helioseismic waves near the solar equator in the presence of magnetic fields deep within the solar radiative zone. We find that reasonable magnetic fields can significantly alter the shapes of the wave profiles for helioseismic g-modes. They can do so because the existence of density gradients allows g-modes to resonantly excite Alfven waves, causing mode energy to be funnelled along magnetic field lines, away from the solar equatorial plane. The resulting wave forms show comparatively sharp spikes in the density profile at radii where these resonances take place. We estimate how big these waves might be in the Sun, and perform a first search for observable consequences. We find …
Supercritical hydrothermal synthesis of ZnO nanopowders beyond the critical point : understanding of nucleation and growth steps
2014
The supercritical hydrothermal synthesis of nanopowders (especially metal oxide) has been widely studied. To the best of our knowledge, no nanoparticle formation mechanism has been published yet. In this prospect, this study is dedicated to the understanding of metal oxide nanoparticle nucleation and growth mechanisms. For this purpose, zinc oxide is used as a model material. First, the influence of synthesis operating conditions such as pressure, temperature, pH, precursor concentrations and solution flow rates on particle morphological properties (size, particle size distribution or morphologies) has been investigated. Hence, two approaches have simultaneously been carried out. The first …
Modified Landau levels, damped harmonic oscillator and two-dimensional pseudo-bosons
2010
In a series of recent papers one of us has analyzed in some details a class of elementary excitations called {\em pseudo-bosons}. They arise from a special deformation of the canonical commutation relation $[a,a^\dagger]=\1$, which is replaced by $[a,b]=\1$, with $b$ not necessarily equal to $a^\dagger$. Here, after a two-dimensional extension of the general framework, we apply the theory to a generalized version of the two-dimensional Hamiltonian describing Landau levels. Moreover, for this system, we discuss coherent states and we deduce a resolution of the identity. We also consider a different class of examples arising from a classical system, i.e. a damped harmonic oscillator.