Search results for "ASAT"

The Endovascular Management of an Iatrogenic Superior Gluteal Artery Rupture Following Bone Marrow Biopsy

2017

We herein report an uncommon case of a life-threatening retroperitoneal hematoma after a bone marrow biopsy. Two hours after iliac crest bone harvesting, the patient experienced syncope and severe hypotension. Urgent contrast-enhanced computed tomography demonstrated extravasation from the superior gluteal artery. Transcatheter coil embolization was performed successfully, without complications. Life-threatening complications caused by retroperitoneal bleeding after bone marrow biopsy are very rare. There are few reports on the use of endovascular treatment in the management of life-threatening hemorrhagic complications after bone marrow biopsy.

El joc educatiu com recurs didàctic en l’ensenyament d’un mòdul d’Agrojardineria en Formació Professional Bàsica

2020

S'investiguen els resultats de l'aplicació de ferramentes basades en l'aplicació de tècniques de Gamificació i Aprenentatge basat en jocs en l'aprenentatge de continguts i en la motivació de l'alumnat de Formació Professional Bàsica en Agrojardineria i Composicions Florals. L'aplicació en realitza en un mòdul de primer curs i es pren una mostra experimental d'alumnat, als que s'aplica les ferramentes objecte d'investigació, i altre grup control per comparar. In the thesis are investigated the results of the application of tools based on the application of techniques Gamification and Games Based Learning in the learning of contents and the motivation of the students of Basic Vocational Train…

Enhanced Permeability and Retention-like Extravasation of Nanoparticles from the Vasculature into Tuberculosis Granulomas in Zebrafish and Mouse Mode…

2018

The enhanced permeability and retention (EPR) effect is the only described mechanism enabling nanoparticles (NPs) flowing in blood to reach tumors by a passive targeting mechanism. Here, using the transparent zebrafish model infected with Mycobacterium marinum we show that an EPR-like process also occurs allowing different types of NPs to extravasate from the vasculature to reach granulomas that assemble during tuberculosis (TB) infection. PEGylated liposomes and other NP types cross endothelial barriers near infection sites within minutes after injection and accumulate close to granulomas. Although similar to 100 and 190 nm NPs concentrated most in granulomas, even similar to 700 nm liposo…

Circulating Tumor Cells (CTCs): A Unique Model of Cancer Metastases and Non-invasive Biomarkers of Therapeutic Response

2021

Late-stage cancer metastasis remains incurable in the clinic and is the major cause death in patients. Circulating tumor cells (CTCs) are thought to be metastatic precursors shed from the primary tumor or metastatic deposits and circulate in the blood. The molecular network regulating CTC survival, extravasation, and colonization in distant metastatic sites is poorly defined, largely due to challenges in isolating rare CTCs. Recent advances in CTC isolation and ex vivo culture techniques facilitates single-cell omics and the development of related animal models to study CTC-mediated metastatic progression. With these powerful tools, CTCs can potentially be used as non-invasive biomarkers pr…

Książki poddane w 1841 r. cenzurze prewencyjnej. Przyczynek źródłowy do dziejów bibliotek klasztorów skasowanych na mocy ukazu z 1832 r. w guberniach…

2014

In Vivo Studies on the Anti-Inflammatory Activity of Pachymic and Dehydrotumulosic Acids

2000

Pachymic and dehydrotumulosic acids were studied in different models of acute and chronic inflammation. They proved to be active in most of the methods applied. None of them were active against arachidonic acid-induced ear edema. Dehydrotumulosic acid significantly diminished the mouse ear edema induced by ethyl phenylpropiolate, while pachymic acid was ineffective. When the putative corticoid-like mechanism of both compounds was explored, pachymic acid activity was partially abolished by the glucocorticoid receptor antagonist progesterone, but dehydrotumulosic acid activity was not affected. In vivo experiments demonstrated the inhibition by both principles of the phospholipase A2 (PLA2)-i…

Restoration of cerebral and systemic microvascular architecture in APP/PS1 transgenic mice following treatment with Liraglutide™.

2015

OBJECTIVE: Cerebral microvascular impairments occurring in AD may reduce Aβ peptide clearance and impact upon circulatory ultrastructure and function. We hypothesized that microvascular pathologies occur in organs responsible for systemic Aβ peptide clearance in a model of AD and that Liraglutide (Victoza(®)) improves vessel architecture. METHODS: Seven-month-old APP/PS1 and age-matched wild-type mice received once-daily intraperitoneal injections of either Liraglutide or saline (n = 4 per group) for eight weeks. Casts of cerebral, splenic, hepatic, and renal microanatomy were analyzed using SEM. RESULTS: Casts from wild-type mice showed regularly spaced microvasculature with smooth lumenal…

Rötliche Lidschwellung nach Dakryozystographie

2000

Neuropeptides, neurogenic inflammation and complex regional pain syndrome (CRPS)

2008

This review explains symptoms and nature of neuropeptide signaling and its importance for clinical symptoms of CRPS. Neurogenic inflammation regularly accompanies excitation of primary afferent nociceptors. It has two major components-plasma extravasation and vasodilatation. The most important mediators are the calcitonin gene-related peptide (CGRP) and substance P (SP). After peripheral trauma immune reaction (e.g. cytokines) and the attempts of the tissue to regenerate (e.g. growth factors) sensitize nociceptors and amplify neurogenic inflammation. This cascade of events has been demonstrated in rat models of CRPS. Clinical findings in these animals strongly resemble clinical findings in …

Spuścizna pojezuicka w zasobach Centralnego Państwowego Archiwum Historycznego we Lwowie

2018

W zasobach Państwowego Archiwum Historycznego Ukrainy we Lwowie źródła odnoszące się do jezuitów dotyczą różnych części Galicji, a w niektórych przypadkach także terenów poza jej granicami. Większość jednostek archiwalnych zawierających dokumenty z okresu kasat zakonu nie jest powszechnie znana, a niektóre z nich prawdopodobnie nigdy nie były wykorzystywane. Zaprezentowane w artykule dokumenty mogą zainteresować historyków sztuki, a także historyków kultury materialnej lub historyków medycyny. Część z nich może okazać się przydatna także w badaniach nad przed- i pokasatowym stanem posiadania jezuitów w zaborze austriackim i poza jego granicami. Szeroki zakres chronologiczny i bogactwo tego …