Search results for "ASBESTO"

Diagnostic and prognostic value of three micrornas in environmental asbestiform fibers-associated malignant mesothelioma

2021

Fluoro-edenite (FE) is an asbestiform fiber identified in Biancavilla (Sicily, Italy). Environmental exposure to FE has been associated with a higher incidence of malignant mesothelioma (MM). The present study aimed to validate the predicted diagnostic significance of hsa-miR-323a-3p, hsa-miR-101-3p, and hsa-miR-20b-5p on a subset of MM patients exposed to FE and matched with healthy controls. For this purpose, MM tissues vs. nonmalignant pleura tissues were analyzed through droplet digital PCR (ddPCR) to evaluate differences in the expression levels of the selected miRNAs and their MM diagnostic potential. In addition, further computational analysis has been performed to establish the corr…

Solastalgia's mourning and the slowly evolving effect of asbestos pollution: A qualitative study in Italy

2019

In Italy, the problem of asbestos pollution is increasing in severity. In fact, in recent years, the number of people affected by asbestos-related illnesses has been growing because of the fibre's slowly evolving effects and its progressive pollution in the environment adjacent to the places where it is processed. Even though the physical consequences of asbestos are now quite clear, few studies have examined the psychological consequences of this kind of disaster. Since it is difficult to perceive its pathogenicity in daily life, this study was conducted in the affected areas of north-eastern Italy, using the qualitative research in psychology with 51 persons who experienced asbestos-relat…

Occupational Diseases: Asbestosis and Mesothelioma in Forensic Practice

2019

Diagnosis of occupational diseases, a strong collaboration between radiologic and clinical features with related occupational history and literature supporting, and an association between the exposure and the disease process are requested. Further pathological findings emerging at biopsy or autopsy, which are considered ancillary examination techniques, may assist in the judgment related to causal chain reconstruction.

Survey sulle patologie asbesto-correlate osservate in una realtà italiana fortemente associata ad esposizione professionale ad amianto.

2011

Obiettivi La Sicilia tra il 1993 ed il 2004 è stata la quinta regione italiana per numero di mesoteliomi. Inoltre, la Provincia di Palermo presenta il maggior numero di casi incidenti in tutta la Regione nel sesso maschile, ed è storicamente caratterizzata da una forte esposizione lavorativa ad amianto (cantieristica navale e ferroviaria). Partendo da questi presupposti, l’obiettivo principale del seguente lavoro è quello di effettuare un’analisi dei casi di asbestosi, placche pleuriche, carcinoma polmonare e mesotelioma asbesto-correlati osservati a Palermo e provincia nel periodo 2005-2009. Metodi Sono stati presi in esame i casi di patologia asbesto-correlata oggetto di delega di indagin…

Patologie asbesto-correlate osservate a Palermo e Provincia tra lavoratori esposti ad amianto [Asbestos-related diseases observed in Palermo (Italy) …

2011

È stato realizzato uno studio su lavoratori professionalmente esposti ad amianto con l'obiettivo di esaminare i casi di patologia asbesto-correlata nella Provincia di Palermo tra il 2005 e il 2009. I dati sono stati raccolti dalle cartelle cliniche e dai verbali delle deleghe di indagine da parte delle Procure di Palermo e di Termini Imerese al Servizio di Prevenzione e Sicurezza negli Ambienti di Lavoro dell'Azienda Sanitaria Provinciale (ASP 6) di Palermo. La regressione logistica multinomiale evidenzia una associazione significativa tra fumo di tabacco e carcinoma polmonare e tra coloro che hanno cominciato a lavorare precocemente e la presenza di asbestosi e placche pleuriche. La casist…

RISK OF EXPOSURE TO ASBESTOS IN CASE OF THE MECHANICAL DEGRADATION OF SOME ASBOCEMENT COMPOSITES

2011

Asbestos: use, bans and disease burden in Europe

2014

To analyse national data on asbestos use and related diseases in the European Region of the World Health Organization (WHO).For each of the 53 countries, per capita asbestos use (kg/capita/year) and age-adjusted mortality rates (deaths/million persons/year) due to mesothelioma and asbestosis were calculated using the databases of the United States Geological Survey and WHO, respectively. Countries were further categorized by ban status: early-ban (ban adopted by 2000, n = 17), late-ban (ban adopted 2001-2013, n = 17), and no-ban (n = 19).Between 1920-2012, the highest per capita asbestos use was found in the no-ban group. After 2000, early-ban and late-ban groups reduced their asbestos use …

Early effects of fluoro-edenite: correlation between IL-18 serum levels and pleural and parenchymal abnormalities.

2016

Fluoro-edenite (FE) is a natural mineral asbestos-like fibrous species first isolated in Biancavilla, Sicily. In order to clarify potential involvement of IL-18 in the pathogenesis of FE-induced chest abnormalities, we analyzed IL-18 serum levels in FE-exposed workers (FEEW) and correlated them with pleural and parenchymal abnormalities. A total of 21 FEEWs, residing in Biancavilla for >30 years, with a working seniority of 17 ± 6.1 years were examined. High-resolution computed tomography scans revealed low grade of fibrosis in 8 (38%) FEEWs, and pleural plaques (PPs) in 13 (62%) FEEWs. The mean IL-18 level was 203.13 ± 90.43 pg/ml. Pearson correlation showed a significant association (…

Symptom burden in mesothelioma patients admitted to home palliative care

2016

Context: Mesothelioma is a very aggressive cancer that is brought on by asbestos exposure. Because there is a long latency period between exposure to asbestos and symptoms of disease, most patients with mesothelioma present with advanced disease and survive an average of 8–12 months. Thus, best supportive care should be considered critical to optimally manage these patients. Aim: The aim of this study was to examine the epidemiological characteristics and symptom burden of mesothelioma patients when admitted to home palliative care. Methods: The charts of a consecutive sample of patients admitted to the home palliative care program with a diagnosis of mesothelioma in an endemic industrial…

Reassessing Accuracy Rates of Median Decisions

2007

We show how Bruno de Finetti''s fundamental theorem of prevision has computable applications in statistical problems that involve only partial information. Specifically, we assess accuracy rates for median decision procedures used in the radiological diagnosis of asbestosis. Conditional exchangeability of individual radiologists'' diagnoses is recognized as more appropriate than independence which is commonly presumed. The FTP yields coherent bounds on probabilities of interest when available information is insufficient to determine a complete distribution. Further assertions that are natural to the problem motivate a partial ordering of conditional probabilities, extending the computation …