Search results for "ASD"

Autism and Migraine: An Unexplored Association?

2020

Autism spectrum disorder is characterized by neurological, psychiatric and medical comorbidities—some conditions co-occur so frequently that comorbidity in autism is the rule rather than the exception. The most common autism co-occurring conditions are intellectual disability, language disorders, attention-deficit hyperactivity disorder, epilepsy, gastrointestinal problems, sleep disorders, anxiety, depression, obsessive-compulsive disorder, psychotic disorders, oppositional defiant disorder, and eating disorders. They are well known and studied. Migraine is the most common brain disease in the world, but surprisingly only a few studies investigate the comorbidity between autism and migrain…

THU0573 Association Between Sosiodemogapic Data and Perceived Health Status on Sexual Activity in Patients with Axial Spondyloarthritis

2013

Background Axial spondyloarthritis (ax-SpA) is a chronic inflammatory disorder causing signs and symptoms from the axial skeleton, but may also affect peripheral joints, tendons and internal organs. Ax-SpA may give rise to significant loss of function and impaired quality of life. Despite the known importance of sexuality as part of quality of life (Healey 2009), only a few studies have explored sexuality in ax-SpA patients. Objectives To investigate the association between sosiodemograpic data and perceived health status on sexual activity in patients with ax-SpA. Methods Patients with ax-SpA (fulfilling the axial SpA criteria) were consecutively recruited from one clinic in southern and o…

Endocrine Disruptors and Autism Spectrum Disorder in Pregnancy: A Review and Evaluation of the Quality of the Epidemiological Evidence

2018

Exposure to environmental contaminants during pregnancy has been linked to adverse health outcomes later in life. Notable among these pollutants are the endocrine disruptors chemicals (EDCs), which are ubiquitously present in the environment and they have been measured and quantified in the fetus. In this systematic review, our objective was to summarize the epidemiological research on the potential association between prenatal exposure to EDCs and Autism Spectrum Disorder (ASD) published from 2005 to 2016. The Navigation Guide Systematic Review Methodology was applied. A total of 17 studies met the inclusion criteria for this review, including: five cohorts and 12 case-control. According t…

Artwork : a Conceptually Organized Reality

2011

A10.8 Evaluation of Disease Activity in Adult Patients with Juvenile Idiopathic Arthritis

2013

Background Juvenile idiopathic arthritis (JIA) is a disease which maintains specific childish rheumatological features during whole life. There is still an open discussion which criteria of the disease activity should be used for the management of adult patients with JIA. Objectives To analyse the usefulness of known disease activity and functional indices used in adult rheumatological practise for the assessment of rheumatoid arthritis (RA) and spondyloarthritidies (SpA): disease acitivity score (DAS), disease acitivity score 28 (DAS28), Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), Bath Spondylitis Functional Index (BASFI), Health Assessment Questionnaire – disability index…

Combinatorial and independent effects of exercise and myostatin/activin blocking on muscle gene expression profiling

2013

The administration of soluble ligand binding domain of type IIb activin receptor fused to the Fc domain (sActRIIB-Fc) has been recently shown to attenuate dystrophic pathology and to increase muscle mass, but also to supress aerobic metabolism. In contrast, aerobic exercise is known for promoting aerobic capacity. The aim of the present thesis was to investigate the effects of the combination of myostatin/activin blocking and aerobic exercise on muscle gene expression profile of a in Duchenne Muscular Dystrophy (DMD) model, the mdx mouse. Microarray analysis was conducted from the gastrocnemius muscle and Gene Set Enrichement Analysis (GSEA) was performed to examine the effects of the treat…

Digitālo rīku izmantošanas iespējas 5. klases matemātikas mājasdarbos

2022

Diplomdarbā Digitālo rīku izmantošanas iespējas 5. klases matemātikas mājasdarbos darba autore Marika Tereščenko aktualizējusi matemātikas nozīmi mācību procesā, kā arī digitālo rīku izmantošanas iespējas mājasdarbu izpildē. Diplomdarba mērķis ir noskaidrot, vai digitālo rīku izmantošana mājasdarbu pildīšanā nemazina mājasdarbu nozīmi un kvalitāti. Pētījumā ir izmantotas vairākas metodes: teorētiskās izpētes metode, aprakstošā metode, atsevišķos gadījumos ir izmantota arī salīdzināmā un kvantitatīvā metode. Pētījuma ietvaros tika noskaidrots par digitālo rīku iespējām izmantot matemātikas mājasdarbu pildīšanā 5.klasē par daļām un jauktajiem skaitļiem. Khan Academy ir visatbilstošākais, jo t…

Poznawczo-behawioralne programy terapeutyczne wykorzystywane w pracy z wymagającymi wsparcia adolescentami z zaburzeniami ze spektrum autyzmu (ASD L1…

2020

Artykuł zawiera opis wybranych metod poznawczo-behawioralnych wykorzystywanych w pracy z wymagającą wsparcia młodzieżą z zaburzeniami ze spektrum autyzmu (ASD L1). We wstępie opisano pokrótce historię zaburzenia i podstawowe problemy występujące u dzieci i młodzieży ze spektrum zaburzeń autystycznych. W dalszej części przytoczono informacje na temat technik poznawczo-behawioralnych często stosowanych w pracy z tymi adolescentami. Omówiono przykładowe programy treningów umiejętności społecznych: PEERS (Program for the Education and Enrichment of Relationship Skills) oraz MASSI (Multimodal Anxiety and Social Skills Intervention). Przybliżono dwa programy wykorzystywane w pracy nad rozwijaniem…

Koku un krūmu pavasara fenoloģisko fāžu izmaiņas Latvijā

2016

Bakalaura darba galvenais mērķis bija izanalizēt parastās ievas Padus racemosa ilgtermiņa tendences kopš 1927.gada, kā arī raksturot āra bērza Betula pendula, parastās lazdas Corylus avellana, baltalkšņa Alnus incana un parastā pīlādža Sorbus aucuparia pavasara fenoloģisko fāžu reģionālās izmaiņas Latvijā references periodā (1981.-2010.gads), izmantojot brīvprātīgo novērotāju vēsturiskos datus. Veikta digitālo fotoattēlu reģionāla analīze parastās ievas Padus racemosa fāzēm 2015. un 2016.gadā, izmantojot portāla Dabasdati.lv datu bāzi. Periodā no 1981.gada līdz 2010.gadam ir novērojams, ka pavasara fenoloģiskās fāzes iestājušās par 2-17 dienām agrāk, nekā laika posmā no 1971.-2000.gadam. Pa…

Cancer invasion ad metastasis: discovering new targets for diagnosis and therapeutics

2009

Cancer invasion and metastases are the hallmarks of malignant tumors and the cause of most cancer deaths. Molecular alterations that arise during cancer progression and that generate abnormal gene products, activated signal transduction pathways, and altered cancer cell-host stroma interactions can be considered targets of therapeutic drugs. Some of these drugs have already entered clinical trials, while others have shown promising results. In this review, we examine some of the successive steps of the metastatic process: cancer cell migration and invasion of the tumor microenvironment, angiogenesis and following extravasation focusing on the deranged signalling pathways underlying the mali…