Search results for "ASEM"

Number III Mucous membrane pemphigoid

2005

Mucous membrane pemphigoid (MMP) is a sub-epithelial vesiculobullous disorder. It is now quite evident that a number of sub-epithelial vesiculobullous disorders may produce similar clinical pictures, and also that a range of variants of MMP exist, with antibodies directed against various hemidesmosomal components or components of the epithelial basement membrane. The term immune-mediated sub-epithelial blistering diseases (IMSEBD) has therefore been used. Immunological differences may account for the significant differences in their clinical presentation and responses to therapy, but unfortunately data on this are few. The diagnosis and management of IMSEBD on clinical grounds alone is impo…

Archaeological excavation confirms the geophysical anomalies recorded at the cathedral of tarragona - A comparative study

2011

An integrated geophysical survey was conducted in September 2007 at the Cathedral of Tarragona to search for archaeological remains of the Roman temple dedicated to the Emperor Augustus. Many hypotheses about its location have been put forward, the most recent ones suggesting it could be inside the present cathedral. A project including Electrical resistivity tomography (ERT) and Ground probing radar (GPR) was planned for a year and conducted during a week of intensive field survey. Both ERT and GPR provided detailed information about subsoil structures. Different ERT techniques and arrays were used, ranging from standard Wenner-Schlumberger 2D sections to full 3D electrical imaging using t…

Jäniksen ja kilpikonnan kilpajuoksu : romanttisen kirjallisuuden formula Anita Brooknerin romaaneissa A start in life ja Hotel du Lac

2001

"I had rather be a thing than an angel." : a comparative study of Jane Austen's and Charlotte Brontë's views on women's status in Victorian society

2001

Handling Evolving Data Warehouse Requirements

2015

A data warehouse is a dynamic environment and its business requirements tend to evolve over time, therefore, it is necessary not only to handle changes in data warehouse data, but also to adjust a data warehouse schema in accordance with changes in requirements. In this paper, we propose an approach to propagate modified data warehouse requirements in data warehouse schemata. The approach supports versions of data warehouse schemata and employs the requirements formalization metamodel and multiversion data warehouse metamodel to identify necessary changes in a data warehouse.

Evolution-Oriented User-Centric Data Warehouse

2011

Data warehouses tend to evolve, because of changes in data sources and business requirements of users. All these kinds of changes must be properly handled, therefore, data warehouse development is never-ending process. In this paper we propose the evolution-oriented user-centric data warehouse design, which on the one hand allows to manage data warehouse evolution automatically or semi-automatically, and on the other hand it provides users with the understandable, easy and transparent data analysis possibilities. The proposed approach supports versions of data warehouse schemata and data semantics.

Mechanisms of tumor invasion: evidence from in vivo observations.

1985

The major mechanisms of tumor invasion in vivo are discussed in the present review. A special emphasis is placed on tumor dedifferentiation which has proved to be of paramount importance for the invasion process. Based on in vivo observations obtained from various human and animal tumors a concept for the mechanism of tumor invasion is proposed which mainly comprises the following basic events: the first and essential step in tumor invasion is the tumor dedifferentiation and dissociation at the invasion front. This apparently temporary and reversible process mobilizes the tumor cells out of the main tumor bulk and enables them to invade the host tissue by active locomotion. This mechanism i…

Absence of regular alpha2(I) collagen chains in colon carcinoma biopsy fragments.

1998

The extracellular matrix (ECM) is known to play an active role in numerous biological processes such as differentiation, apoptosis and cancer. Extensive alterations of epithelial basement membranes and of interstitial ECM are known to occur during the progression of most invasive carcinomas. Collagen, which represents the major component of the interstitial ECM, is primarily involved in the stromal changes at the site of tumor cell invasion. We have previously described the occurrence in breast and colon cancer ECM of an oncofetal form of collagen, characterized by an acidic chain distinct from those of type I and III collagen. In the present paper, we bring evidence that alpha2(I) collagen…

Zur Ultrastruktur des Neurofibroms

1970

Elektronenmikroskopische Untersuchung eines Neurofibroms von einem 72 jahrigen Mann mit Morbus Recklinghausen. Der Tumor besteht aus verzweigten Schwannschen Zellen, die in ein kollagenfasriges Zwischengewebe eingelagert sind. Die Schwannschen Zellen sind von einer Basalmembran und einen Reticulinfasernetz umgeben. Wahrscheinlich sind die Schwannschen Zellen eines Neurofibroms befahigt fibrillare Zwischensubstanz zu bilden.

Oblique collision and evolution of large-scale transcurrent shear zones in the Kaoko belt, NW Namibia

2005

Abstract Early structures in the central part of the Kaoko orogenic belt of NW Namibia suggest that the initial stage of collision was governed by underthrusting of the medium-grade Central Kaoko zone below the high-grade Western Kaoko zone, resulting in the development of an inverted metamorphic gradient. In the Western zone, early structures were overprinted by a second phase of deformation, which is associated with localization of the transcurrent Puros shear zone along the contact between the Western and Central zones. During this second phase, extensive partial melting and intrusion of ∼550 Ma granitic bodies occurred in the high-grade Western zone. In the Central zone, the second phas…