Search results for "ASES"
showing 10 items of 26804 documents
Estudios estratégicos para la lucha contra la fascioliasis humana a nivel mundial = Strategic studies for the fight against de human fascioliasis wor…
2013
Fascioliasis is a zoonotic parasitic disease caused by Fasciola hepatica and F. gigantica. Emergence of human fascioliasis prompted a worldwide control initiative including a pilot study in several countries. Given the necessity to characterize the fasciolid populations involved, the overall aim of the present research is, first, the phenotypic characterization of faciolid adults and eggs implicated in human endemic areas, where this initiative has been implemented, through a computer image analysis system (CIAS) applied on the basis of standardized measurements. Second, new immunological techniques and their potential use as immunological diagnostic tests in those areas are evaluated. The …
Targeted Drug Delivery in Plants: Enzyme‐Responsive Lignin Nanocarriers for the Curative Treatment of the Worldwide Grapevine Trunk Disease Esca
2019
Abstract Nanocarrier (NC)‐mediated drug delivery is widely researched in medicine but to date has not been used in agriculture. The first curative NC‐based treatment of the worldwide occurring grapevine trunk disease Esca, with more than 2 billion infected plants causing a loss yearly of $1.5 billion, is presented. To date, only repetitive spraying of fungicides is used to reduce chances of infection. This long‐term treatment against Esca uses minimal amounts of fungicide encapsulated in biobased and biodegradable lignin NCs. A single trunk injection of <10 mg fungicide results in curing of an infected plant. Only upon Esca infection, ligninolytic enzymes, secreted by the Esca‐associated fu…
Drug Delivery in Plants: Targeted Drug Delivery in Plants: Enzyme-Responsive Lignin Nanocarriers for the Curative Treatment of the Worldwide Grapevin…
2019
In article number 1802315, Jochen Fischer, Frederik R. Wurm, and co‐workers report the first nanocarrier‐mediated drug delivery in plants. Enzyme‐degradable lignin nanocarriers are injected into the trunks of grapevine plants. They release a fungicide selectively inside of the plants and are able to cure the worldwide fungal plant disease Esca for the first time. This strategy will reduce the extensive spraying of pesticides in agriculture. Image credit: Katharina Maisenbacher.
Characterization of thin plastic foils for applications in X-ray optics technology
2007
Thin plastic foils are being investigated to build shell optics for X-ray telescopes. Compared to polished glass optics, the advantage is in terms of increased collecting area, light weight and lower cost. Plastic material is also desirable to allow deformation into a complete surface of revolution. We collected plastic materials of common use for industrial applications and also specialty materials developed for the electronic industry. A comparative study was then performed to evaluate the optical quality of the selected plastic films. Surface analysis was carried out with topographic instruments to investigate the microroughness of our samples at different scan lengths. Preliminary resul…
Impact of Platelet Reactivity in ACS Patients on Clinical Outcomes with Triple Antithrombotic Therapy
2021
Optimal antithrombotic therapy after percutaneous coronary intervention (PCI) in patients on oral anticoagulants (OAC) remains a clinical conundrum. In fact, combining an OAC with dual antiplatelet therapy (triple antithrombotic therapy, TAT) increases the risk of bleeding. Clopidogrel is the only thienopyridine recommended in TAT patients. Whether its response plays a relevant role in this setting remains uncertain. We aimed to evaluate the level of platelet reactivity inhibition (PRI) achieved by oral TAT in Acute Coronary Syndrome (ACS) patients undergoing PCI and its relationship with outcomes. We performed a multicenter prospective observational study and assessed PRI by vasodilator-st…
Plasmacytoid myoepithelioma of the palate : report of one case and review of the literature
2007
Introduction: Myoepithelioma is a benign neoplasm of salivary glands, represents 1.5 % of all salivary glands neoplasm. The plasmacytoid myoepithelioma from palate salivary glands is considered as a rare entity, at date it has been reported 14 cases. It is present one case of plasmacytoid myoepithelioma of palate. Case report: A Hispanic female of 28 years old presented a not-ulcerate, painless ovoid swelling at left side of hard palate with a one year and a half of evolution. An excisional biopsy was done. The sample was fixed at 10% buffer formalin, embedded in paraffin, cuts at 5 µ and stained with H-E. Microscopically, the lesion was composed by myoepithelial neoplastic cells characteri…
Síntesis y caracterización de poliuretanos termoplásticos basados en policarbonato dioles. Relación estructura/propiedades.
2012
Los poliuretanos son una familia de polímeros muy versátil, utilizados en un amplio rango de aplicación, desde las espumas rígidas-flexibles, materiales elastómeros, recubrimientos, adhesivos, hasta materiales con aplicaciones biomédicas. Esta gran versatilidad es debida a que los reactivos utilizados en la síntesis de los poliuretanos son muy variados, permitiendo la gran versatilidad en la formulación del poliuretano y en las propiedades del mismo. Los poliuretanos termoplásticos elastómeros son copolímeros de bloque, que a temperatura ambiente se comportan como elastómeros entrecruzados, y sin embargo a diferencia de los elastómeros convencionales, por acción del calor se pueden conforma…
Alder pollen in Finland ripens after a short exposure to warm days in early spring, showing biennial variation in the onset of pollen ripening
2017
We developed a temperature sum model to predict the daily pollen release of alder, based on pollen data collected with pollen traps at seven locations in Finland over the years 2000–2014. We estimated the model parameters by minimizing the sum of squared errors (SSE) of the model, with weights that put more weight on binary recognition of daily presence or absence of pollen. The model results suggest that alder pollen ripens after a couple of warm days in February, while the whole pollen release period typically takes up to 4 weeks. We tested the model residuals against air humidity, precipitation and wind speed, but adding these meteorological features did not improve the model prediction …
Endocrine disrupters: the new players able to affect the epigenome
2015
Epigenetics represents the way by which the environment is able to program the genome; there are three main levels of epigenetic control on genome: DNA methylation, post-translational histone modification and microRNA expression. The term Epigenetics has been widened by NIH to include “both heritable changes in gene activity and expression but also stable, long-term alterations in the transcriptional potential of a cell that are not necessarily heritable.” These changes might be produced mostly by the early life environment and might affect health influencing the susceptibility to develop diseases, from cancer to mental disorder, during the entire life span. The most studied environmental i…
Additional file 6: of Male breast cancer in BRCA1 and BRCA2 mutation carriers: pathology data from the Consortium of Investigators of Modifiers of BR…
2016
Pathology of invasive MBCs in the general population from SEER and BRCA1 MBCs and ORs in predicting male BRCA1 mutation carrier status. (DOCX 19 kb)