Search results for "ASES"
showing 10 items of 26804 documents
Association between resting blood pressure and maximal blood pressure response to exercise and arterial health
2022
We investigated the longitudinal associations of blood pressure, cardiorespiratory fitness, and arterial stiffness among children. Arterial stiffening has been repeatedly shown to be a cardiovascular mortality predictor and can be observed early in childhood. As such, it is crucial to understand whether a child’s blood pressure, fitness level, and body composition can predict early signs of atherosclerosis and arterial stiffening. The current study examined the relationship between blood pressure, cardiorespiratory fitness, and arterial stiffness over time in children, using data from the Physical and Nutrition in Children (PANIC) Study. It is a physical and dietary intervention study condu…
Habitual physical activity and heart rate variability in 12-year old children
2012
ABSTRACT Wennman, Heini 2012. Habitual physical activity and heart rate variability in 12-year old children. Department of Biology of Physical Activity, University of Jyväskylä, 92p. The study of heart rate variability (HRV) provides useful information about the function of the cardiac autonomic nervous system. The effects of many environmental factors on HRV are well known, but the associations between physical activity (PA) and HRV, especially in children, are less investigated. Higher HRV is related to health and many pathologic conditions are associated with reduced HRV. Exercise causes HRV to diminish, but improves HRV in long term. PA promotes many health related changes in energy met…
Riesz-Fischer Maps, Semi-frames and Frames in Rigged Hilbert Spaces
2021
In this note we present a review, some considerations and new results about maps with values in a distribution space and domain in a σ-finite measure space X. Namely, this is a survey about Bessel maps, frames and bases (in particular Riesz and Gel’fand bases) in a distribution space. In this setting, the Riesz-Fischer maps and semi-frames are defined and new results about them are obtained. Some examples in tempered distributions space are examined.
Formulas for the thermodynamic properties of dense nitrogen.
1969
Towards Controlled Synthesis of Water-Soluble Gold Nanoclusters : Synthesis and Analysis
2019
Water-soluble gold nanoclusters with well-defined molecular structures and stability possess particular biophysical properties making them excellent candidates for biological applications as well as for fundamental spectroscopic studies. The currently existing synthetic protocols for atomically monodisperse thiolate-protected gold nanoclusters (AuMPCs) have been widely expanded with organothiolates, yet the direct synthesis reports for water-soluble AuMPCs are still deficient. Here, we demonstrate a wet-chemistry pH-controlled synthesis of two large water-soluble nanoclusters utilizing p-mercaptobenzoic acid (pMBA), affording different sizes of plasmonic AuMPCs on the preparative scale (∼7 …
Gingivitis
2014
Gingival inflammation is caused by bacterial plaque (dental biofilm) that accumulates daily on the teeth. Results in redness, slight swelling, or "puffiness" of the gums and bleeding on tooth brushing. Treatment involves thorough professional tooth cleaning and effective daily removal of dental plaque by tooth brushing and cleaning between the teeth. Necrotizing ulcerative gingivitis (NUG) is a more serious condition that is mainly found in developing countries associated with people with severe malnutrition or HIV/AIDS with low CD4 T-cell counts.
Contributions of mean and shape of blood pressure distribution to worldwide trends and variations in raised blood pressure: A pooled analysis of 1018…
2018
Background: Change in the prevalence of raised blood pressure could be due to both shifts in the entire distribution of blood pressure (representing the combined effects of public health interventions and secular trends) and changes in its high-blood-pressure tail (representing successful clinical interventions to control blood pressure in the hypertensive population). Our aim was to quantify the contributions of these two phenomena to the worldwide trends in the prevalence of raised blood pressure. Methods: We pooled 1018 population-based studies with blood pressure measurements on 88.6 million participants from 1985 to 2016. We first calculated mean systolic blood pressure (SBP), mean dia…
Sífilis secundaria en un paciente VIH positivo
2004
La incidencia de afecciones orales, antes infrecuentes en pacientes infectados por VIH, se está incrementando y es posible que se subestime. Las lesiones orales resultantes de la sífilis secundaria son raras; sin embargo, ocurren, y el odontólogo debería ser capaz de realizar un correcto diagnóstico. En algunos casos la anámnesis y los signos clínicos de las lesiones son insuficientes para permitir el diagnóstico de la enfermedad. El conocimiento de sus características histológicas y las pruebas de laboratorio relevantes, así como su aplicabilidad y limitaciones son necesarios para el correcto diagnóstico de la sífilis secundaria. The incidence of oral manifestations of HIV infection is cha…
Dexamethasone premedication suppresses vaccine-induced immune responses against cancer
2020
ABSTRACT Glucocorticosteroids (GCS) have an established role in oncology and are administered to cancer patients in routine clinical care and in drug development trials as co-medication. Given their strong immune-suppressive activity, GCS may interfere with immune-oncology drugs. We are developing a therapeutic cancer vaccine, which is based on a liposomal formulation of tumor-antigen encoding RNA (RNA-LPX) and induces a strong T-cell response both in mice as well as in humans. In this study, we investigated in vivo in mice and in human PBMCs the effect of the commonly used long-acting GCS Dexamethasone (Dexa) on the efficacy of this vaccine format, with a particular focus on antigen-specif…
Functional characterization of the human tRNA methyltransferases TRMT10A and TRMT10B
2020
Abstract The TRM10 family of methyltransferases is responsible for the N1-methylation of purines at position 9 of tRNAs in Archaea and Eukarya. The human genome encodes three TRM10-type enzymes, of which only the mitochondrial TRMT10C was previously characterized in detail, whereas the functional significance of the two presumably nuclear enzymes TRMT10A and TRMT10B remained unexplained. Here we show that TRMT10A is m1G9-specific and methylates a subset of nuclear-encoded tRNAs, whilst TRMT10B is the first m1A9-specific tRNA methyltransferase found in eukaryotes and is responsible for the modification of a single nuclear-encoded tRNA. Furthermore, we show that the lack of G9 methylation cau…