Search results for "ASIS"

Comparison between the MHFEM formulation and a 2nd spatial order FV formulation of the linear groundwater flow problem

2008

Mixed and Mixed Hybrid Finite Elements (MHFE) methods have been widely used in the last decade for simulation of groundwater flow problem, petroleum reservoir problems, potential flow problems, etc. The main advantage of these methods is that, unlike the classical Galerkin approach, they guarantee local and global mass balance, as well the flux continuity between inter-element sides. The simple shape of the control volume, where the mass conservation is satisfied, makes also easier to couple this technique with a Finite Volume technique in the time splitting approach for the solution of advection-dispersion problems. In the present paper a new second spatial approximation order Finite Volum…

Phenotypic characterization and adhesive properties of vaginal Candida spp. strains provided by the CHU Farhat Hached (Sousse, Tunisia).

2015

Abstract Background Vulvovaginal candidiasis is a common infection among women worldwide, being Candida albicans the most commonly isolated species. Therefore, controlling this opportunistic yeast is one of the key factors for reducing nosocomial infection. Aims We investigated several virulence properties of 28 vaginal strains of Candida isolated from Tunisian women suffering from vulvovaginitis. We also analyzed the virulence properties of a clinical Candida krusei strain and five Candida reference strains. Methods Candida strains were subjected to microscopic analysis and culture in Candida ID2 chromogenic medium. The adhesive properties of these strains were estimated by the microtiter …

Enrico Nicolò. Fotogrammi Interiori

2010

El mito de orfeo y euridice en los origenes del melodrama

2019

En el nacimiento de la ópera (el melodrama) el tema elegido de manera mayoritaria fue el del mito de Orfeo, el semidiós cantor porque con este personaje no se rompía la verosimilitud al representar obras totalmente cantadas. Aunque su presencia en el género operístico de los orígenes se debe también a otros factores importantes. La complejidad del personaje, de su historia y características que han hecho de Orfeo un personaje literario, cuya presencia destaca en diferentes obras de autores de todos los tiempos. En la literatura italiana, la influencia de Virgilio, que nos presenta a Orfeo en las Geórgicas, y de Ovidio y sus Metamorfosis fue determinante, pero además el personaje de Orfeo es…

Impact of

2018

Drosophila melanogaster has been for over a century the model of choice of several neurobiologists to decipher the formation and development of the nervous system as well as to mirror the pathophysiological conditions of many human neurodegenerative diseases. The rare disease Friedreich’s ataxia (FRDA) is not an exception. Since the isolation of the responsible gene more than two decades ago, the analysis of the fly orthologue has proven to be an excellent avenue to understand the development and progression of the disease, to unravel pivotal mechanisms underpinning the pathology and to identify genes and molecules that might well be either disease biomarkers or promising targets for therap…

Quasisymmetric extension on the real line

2015

We give a geometric characterization of the sets $E\subset \mathbb{R}$ that satisfy the following property: every quasisymmetric embedding $f: E \to \mathbb{R}^n$ extends to a quasisymmetric embedding $f:\mathbb{R}\to\mathbb{R}^N$ for some $N\geq n$.

Adaptive variable structure fuzzy neural identification and control for a class of MIMO nonlinear system

2013

This paper presents a novel adaptive variable structure (AVS) method to design a fuzzy neural network (FNN). This AVS-FNN is based on radial basis function (RBF) neurons, which have center and width vectors. The network performs sequential learning through sliding data window reflecting system dynamic changes, and dynamic growing-and-pruning structure of FNN. The salient characteristics of the AVS-FNN are as follows: (1) Structure-learning and parameters estimation are performed automatically and simultaneously without partitioning input space and selecting initial parameters a priori. The structure-learning approach relies on the contribution of the size of the output. (2) A set of fuzzy r…

Regulatory cytokine gene polymorphisms and risk of colorectal carcinoma.

2006

It is well established that cancer arises in chronically inflamed tissue, and this is particularly notable in the gastrointestinal tract. Classic examples include Helicobacter pylori-associated gastric cancer, hepatocellular carcinoma, and inflammatory bowel disease-associated colorectal cancer. Growing evidence suggests that these associations might be not casual findings. Focusing on individual cytokines has generated evidence that anti-inflammatory cytokine interleukin (IL)-10 and transforming growth factor-beta1 (TGF-beta1) may have a complex role in gastrointestinal carcinogenesis. As an example, IL-10-deficient mice develop severe atrophic gastritis and a chronic enterocolitis, develo…

24S-hydroxycholesterol and cholesterol-24S-hydroxylase (CYP46A1) in the retina: from cholesterol homeostasis to pathophysiology of glaucoma.

2011

http://www.sciencedirect.com/; International audience; Free cholesterol is the predominant form of cholesterol in the neural retina. The vertebrate neural retina exhibits its own capacity to synthesize cholesterol and meets its demand also by taking it from the circulation. Defects in cholesterol synthesis and trafficking in the neural retina has detrimental consequences on its structure and function, highlighting the crucial importance of maintaining cholesterol homeostasis in the retina. Our purpose was to give a review on the functioning of the retina, the role of cholesterol and cholesterol metabolism therein, with special emphasis on cholesterol-24S-hydroxylase (CYP46A1). Similar to th…

In vivo consequences of cholesterol-24s-hydroxylase (CYP46A1) inhibition by voriconazole on cholesterol homeostasis and function in the rat retina

2011

Cholesterol 24S-hydroxylase (CYP46A1) converts cholesterol into 24S-hydroxycholesterol in neurons and participates in cholesterol homeostasis in the central nervous system, including the retina. We aimed to evaluate the consequences of CYP46A1 inhibition by voriconazole on cholesterol homeostasis and function in the retina. Rats received daily intraperitoneal injections of voriconazole (60mg/kg), minocycline (22mg/kg), voriconazole plus minocycline, or vehicle during five consecutive days. The rats were submitted to electroretinography to monitor retinal functionality. Cholesterol and 24S-hydroxycholesterol were measured in plasma, brain and retina by gas chromatography-mass spectrometry. T…