Search results for "ASIS"

showing 10 items of 4190 documents

Infrastructures et oasis relais migratoires au Sahara algérien

2005

International audience

Algérie[SHS.GEO] Humanities and Social Sciences/GeographyOasis[SHS.GEO]Humanities and Social Sciences/GeographyComputingMilieux_MISCELLANEOUSMigrationSahara[ SHS.GEO ] Humanities and Social Sciences/Geography
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Caracterización de barita cubana y su reducción carbotérmica en horno de microondas

2007

The Cuban Barite (BaSO4) is characterized by X ray diffraction, chemical analysis and scanning electron microscopy. The principal components are identified and its characteristic morphology is shown. Its carbothermic reduction under microwave irradiation is carried out with the purpose of to improve the yield of this stage during the mineral transformation process in reagent of barium of diverse applications. La barita cubana (BaSO4) se ha caracterizado por difracción de rayos X, análisis químico y microscopía electrónica de barrido. Se han identificado sus componentes mayoritarios y así mismo se muestra su morfología característica. Se ha realizado su reducción carbotérmica en horno de mic…

Alkaline earth metalChemistryScanning electron microscopeMetals and AlloysBarium sulfidechemistry.chemical_elementMineralogyBariumMicrowave assisted reductionCondensed Matter PhysicsBaritachemistry.chemical_compoundBariteReducción asistida por microondasReagentMicroscopyX-ray crystallographyMicrowave irradiationMaterials ChemistryBarium sulfideReducción carbotérmicaSulfuro de barioCarbothermic reductionPhysical and Theoretical ChemistryNuclear chemistry
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Allogeneic stem cell transplantation for renal cell carcinoma

2011

Allogeneic hematopoietic stem cell transplantation from a compatible donor has been utilized as adoptive immunotherapy in metastatic, cytokine-refractory renal cell carcinoma (RCC). Since the year 2000, several investigators have established that RCC is susceptible to a graft-versus-tumor effect: they reported that patients with renal cancer may have partial or complete disease responses, in the 20-40% range, after allogeneic transplantation following a reduced-intensity regimen. However, transplant-related mortality is still high in the 10-20% range, and responses are rarely durable. Experimental evidence suggests that donor-derived T cells and natural killer cells are the main mediators o…

Allogeneic transplantationT-Lymphocytesmedicine.medical_treatmentAntineoplastic AgentsHematopoietic stem cell transplantationurologic and male genital diseasesMinor histocompatibility antigenHumansTransplantation HomologousMedicineCytotoxic T cellPharmacology (medical)Molecular Targeted TherapyNeoplasm MetastasisCarcinoma Renal Cellbusiness.industryHematopoietic Stem Cell TransplantationImmunotherapyCombined Modality TherapyKidney NeoplasmsTissue DonorsKiller Cells NaturalTransplantationOncologyImmunologyStem cellbusinessCD8Expert Review of Anticancer Therapy
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Synthesis of polyfluoroalkyl sp2-iminosugar glycolipids and evaluation of their immunomodulatory properties towards anti-tumor, anti-leishmanial and …

2019

Immunomodulatory glycolipids, among which α-galactosylceramide (KRN7000) is an iconic example, have shown strong therapeutic potential in a variety of conditions ranging from cancer and infection to autoimmune or neurodegenerative diseases. A main difficulty for those channels is that they often provoke a cytokine storm comprising both pro- and anti-inflammatory mediators that antagonize each other and negatively affect the immune response. The synthesis of analogues with narrower cytokine secretion-inducing capabilities is hampered by the intrinsic difficulty at controlling the stereochemical outcome in glycosidation reactions, particularly if targeting the α-anomer, which seriously hamper…

Allosteric regulationIminosugar01 natural sciencesImmunomodulation03 medical and health sciencesGlycolipidGlycomimeticDrug DiscoverymedicineLeishmaniasisp38α MAPKCancer030304 developmental biologyInflammationPharmacology0303 health sciences010405 organic chemistryChemistryOrganic ChemistryAutophosphorylationBiological activityGeneral Medicinemedicine.disease0104 chemical sciencessp2-Iminosugar glycolipidsBiochemistryMechanism of actionPolyfluoroalkyl compoundsmedicine.symptomCytokine stormEuropean Journal of Medicinal Chemistry
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Studi greci e latini nell?antica Università di Altamura (1748-1821)

2019

The article tries to highlight, despite the scarse of available documentation, the Greek and Latin studies (language and texts) in the ancient Apulian University in Altamura (1748-1821). Furthermore, on the basis of unpublished archival materials (school registers and student workbooks) it is possible to shed light on the ancient authors explained at school, the teaching methods, and the study practices.

Altamura ? Apulia ? University ? Greek and Latin studies 23 45 https://pages.uv.es/SPhV/cas/numero21.wikiNunzio The article tries to highlightdespite the scarse of available documentationUNESCO::CIENCIAS DE LAS ARTES Y LAS LETRASthe Greek and Latin studies (language and texts) in the ancient Apulian University in Altamura (1748-1821). Furthermoreon the basis of unpublished archival materials (school registers and student workbooks) it is possible to shed light on the ancient authors explained at school//pages.uv.es/SPhV/cas/numero21.wiki [Altamura ? Apulia ? University ? Greek and Latin studies 23 45 https]:CIENCIAS DE LAS ARTES Y LAS LETRAS [UNESCO]and the study practices. Altamura ? Puglia ? Università ? Studi greci e latini1135-9560 8276 Studia philologica valentina 536436 2019 21 7225811 Studi greci e latini nell?antica Università di Altamura (1748-1821) Bianchithe teaching methods
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Identification of a specific type of PD from acoustic emission frequency spectra

2001

The paper presents an attempt to apply spectral analysis tools in processing acoustic emission (AE) pulses generated by partial discharge (FD). The experimental part of the paper describes spark gaps generating four types of PD and specifies parameters of measured acoustic signals and recalls the system used for measurement and analysis of the frequency spectra. Also, a spectral analysis procedure is presented, and frequency-domain descriptors characterizing AE pulses are defined. The results of the analysis are given both as time plots and amplitude and energy density spectra, related to values of the associated descriptors. The spectral analysis results cover AE pulses generated in system…

AmplitudeBasis (linear algebra)Acoustic emissionChemistryFrequency domainAcousticsPartial dischargeSpark gapElectrical and Electronic EngineeringType (model theory)Spectral lineIEEE Transactions on Dielectrics and Electrical Insulation
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The Anabasis of Patrick: Travelling an allegorical narrative map of illness and disability

2018

Abstract Objectives This paper examines the stories of Patrick, a man living with cancer and a spinal cord injury. Design An intrinsic case study was used to address Patrick's experiences. The design of the study is underpinned by narrative dialogism. Method Photo-elicitation interviews were conducted. Visual and verbal data were analysed using a dialogical narrative analysis. Results Patrick aligned his experiences with a story titled Anabasis to organize and express them. Although Anabasis is not a story about illness, it provides Patrick with an allegorical narrative map of how to live with disability and survive illness. Within ‘The Anabasis of Patrick’, the analysis identified three st…

Anabasis030505 public healthPsychoanalysisbiologyDialogical self030229 sport sciencesbiology.organism_classificationNarrative inquiryDevelopmental psychology03 medical and health sciences0302 clinical medicineEmbodied cognitionNarrativeHealth behavior0305 other medical sciencePsychologyPractical implicationsApplied PsychologyStorytellingPsychology of Sport and Exercise
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Systemic schistosomiasis and large bowel perforation: An unexpected surgical urgency. Report of a case and literature review

2019

Key Clinical Message In the presence of suggestive clinical picture (high eosinophil count and multiple CT scan granuloma‐like lesions), schistosomiasis should be taken into account in case of suspected bowel perforation even if common risk factors are not identified through anamnesis.

Anamnesismedicine.medical_specialtyHigh eosinophil countmedicine.diagnostic_testbusiness.industryCase ReportSchistosomiasisComputed tomographyCase ReportsGeneral MedicineBowel perforation030204 cardiovascular system & hematologymedicine.disease03 medical and health sciences0302 clinical medicineEmergency surgery030220 oncology & carcinogenesiscolonic perforationMedicineRadiologyemergency surgerysystemic schistosomiasisbusinessClinical Case Reports
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Receptor Activator of NF-kB (RANK) Expression in Primary Tumors Associates with Bone Metastasis Occurrence in Breast Cancer Patients

2011

Background\ud Receptor activator of NFkB (RANK), its ligand (RANKL) and the decoy receptor of RANKL (osteoprotegerin, OPG) play a pivotal role in bone remodeling by regulating osteoclasts formation and activity. RANKL stimulates migration of RANK-expressing tumor cells in vitro, conversely inhibited by OPG.\ud \ud Materials and Methods\ud We examined mRNA expression levels of RANKL/RANK/OPG in a publicly available microarray dataset of 295 primary breast cancer patients. We next analyzed RANK expression by immunohistochemistry in an independent series of 93 primary breast cancer specimens and investigated a possible association with clinicopathological parameters, bone recurrence and surviv…

Anatomy and PhysiologyMicroarraysSettore MED/06 - Oncologia MedicaCancer TreatmentLigandsMetastasisBone remodelingMetastasisBasic Cancer ResearchBreast TumorsBone and Soft Tissue SarcomasNeoplasm MetastasisMusculoskeletal SystemOligonucleotide Array Sequence AnalysisMultidisciplinaryPredictive markerReceptor Activator of Nuclear Factor-kappa BQRBone metastasisMiddle AgedImmunohistochemistryGene Expression Regulation NeoplasticOncologyRANKLMedicineFemaleResearch Articlemusculoskeletal diseasesmedicine.medical_specialtyHistologyScienceBone NeoplasmsBreast NeoplasmsBiologyBreast cancerAntibody TherapySDG 3 - Good Health and Well-beingOsteoprotegerinInternal medicinemedicineHumansRNA MessengerBoneBiologyAgedBreast cancer bone metastasis RANK-RANKLRANK LigandOsteoprotegerinComputational BiologyCancers and NeoplasmsRANK Ligandmedicine.diseaseEndocrinologyCancer researchbiology.protein
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The Active Human Gut Microbiota Differs from the Total Microbiota

2011

The human gut microbiota is considered one of the most fascinating reservoirs of microbial diversity hosting between 400 to 1000 bacterial species distributed among nine phyla with Firmicutes, Bacteroidetes and Actinobacteria representing around of the diversity. One of the most intriguing issues relates to understanding which microbial groups are active players in the maintenance of the microbiota homeostasis. Here, we describe the diversity of active microbial fractions compared with the whole community from raw human fecal samples. We studied four healthy volunteers by 16S rDNA gene pyrosequencing. The fractions were obtained by cell sorting based on bacterial RNA concentration. Bacteria…

Anatomy and PhysiologyPolymerase Chain ReactionFecesRNA Ribosomal 16SMolecular Cell BiologyHomeostasisCommunity AssemblyIn Situ Hybridization FluorescenceMultidisciplinaryEcologybiologyQRBiodiversityGenomicsFlow CytometryBacterial Typing TechniquesRNA BacterialCommunity EcologyMedical MicrobiologyMedicineResearch ArticleAdultFirmicutesScienceSensitivity and SpecificityMicrobiologyMicrobial EcologyMicrobiologyActinobacteriaHumansMicrobiomeBiologyCommunity StructureBacteriaClostridialesBacteroidetesBacteriologySequence Analysis DNAComparative Genomicsbiology.organism_classificationGastrointestinal TractSpecies InteractionsMetagenomicsMetagenomePyrosequencingMetagenomicsPhysiological ProcessesCytometryBacteriaPLoS ONE
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