Search results for "ASP"
showing 10 items of 4932 documents
Value Co-creation for Smart Villages: The Institutionalization of Regional Service Ecosystems
2020
Building a versatile portfolio of public and private digital-enabled services is vital in rural and sparsely populated regions, where traditional market mechanisms alone cannot guarantee the availability of essential services. However, contemporary services tend to build on prevalent institutions, often governed by decisions based on market mechanisms, such as economies of scale – service-by-service and village-by-village. A shift is suggested towards networks of smart villages co-creating value as regional service ecosystems. We draw from institutional theory and employ the Service-dominant logic (SDL) framework in investigating value co-creation in rural villages in Sweden. Analyzing 53 l…
Valeria Tatano e AA. VV. Oltre la trasparenza.
2012
Recensione del testo di VALERIA TATANO (CURATORE), Oltre la trasparenza. Riflessioni sull’impiego del vetro in architettura, Officina, Roma 2008. La storia del vetro in edilizia coincide con la ricerca della trasparenza: grazie al vetro la luce può entrare negli ambienti che, al tempo stesso, sono protetti dagli agenti atmosferici. Negli ultimi anni, con l’evoluzione tecnologica, abbiamo assistito a una rivoluzione delle possibilità di impiego di tale materiale. Il testo Oltre la trasparenza offre uno scenario completo sui possibili usi innovativi del vetro nell’architettura contemporanea; obiettivo dell’articolo è quello di evidenziare i caratteri essenziali di tale evoluzione.
Vettori polimerici della poliaspartammide coniugati a bisfosfonati per il direzionamento di farmaci alle ossa.
2011
Impegno motivato. Esercizio di decision making "Facciamo la valigia"
2009
Perfektiivisen aspektin esiintyminen suomalaisessa viittomakielessä
2012
Tarkastelen pro gradu -tutkielmassani perfektiivisen aspektin esiintymistä suomalaisessa viittomakielessä. Perfektiivisellä aspektilla tarkoitetaan rajattua tapahtumaa, jossa jokin toiminta on päättynyt tai loppuun suoritettu. Keskityn tutkielmassani kolmeen viittomaan: JO, VALMIS ja LOPPU. Rissanen on esittänyt näillä viittomilla voitavan ilmaista perfektiivistä aspektia suomalaisessa viittomakielessä. Suomalaisessa viittomakielessä esiintyvän perfektiivisen aspektin syvällisemmän tarkastelun puutteen vuoksi tutkielmani keskeisenä tavoitteena on selvittää, että ilmaistaanko viittomilla JO, VALMIS ja LOPPU perfektiivistä aspektia ja millaisissa tilanteissa ja viittomajärjestyksissä se voi t…
Human Papillomavirus Types 16, 18, and 31 Share Similar Endocytic Requirements for Entry
2013
ABSTRACT Human papillomavirus type 18 (HPV18), one of the HPVs with malignant potential, enters cells by an unknown endocytic mechanism. The key cellular requirements for HPV18 endocytosis were tested in comparison to those for HPV16 and -31 endocytoses. HPV18 (like HPV16 and -31) entry was independent of clathrin, caveolin, dynamin, and lipid rafts but required actin polymerization and tetraspanin CD151, and the viruses were routed to the same LAMP-1-positive compartment. Hence, the viruses shared similar cellular requirements for endocytic entry.
The Extracellular δ-Domain is Essential for the Formation of CD81 Tetraspanin Webs
2014
AbstractCD81 is a ubiquitously expressed member of the tetraspanin family. It forms large molecular platforms, so-called tetraspanin webs that play physiological roles in a variety of cellular functions and are involved in viral and parasite infections. We have investigated which part of the CD81 molecule is required for the formation of domains in the cell membranes of T-cells and hepatocytes. Surprisingly, we find that large CD81 platforms assemble via the short extracellular δ-domain, independent from a strong primary partner binding and from weak interactions mediated by palmitoylation. The δ-domain is also essential for the platforms to function during viral entry. We propose that, ins…
Clathrin- and Caveolin-Independent Entry of Human Papillomavirus Type 16—Involvement of Tetraspanin-Enriched Microdomains (TEMs)
2008
BACKGROUND: Infectious entry of human papillomaviruses into their host cells is an important step in the viral life cycle. For cell binding these viruses use proteoglycans as initial attachment sites. Subsequent transfer to a secondary receptor molecule seems to be involved in virus uptake. Depending on the papillomavirus subtype, it has been reported that entry occurs by clathrin- or caveolin-mediated mechanisms. Regarding human papillomavirus type 16 (HPV16), the primary etiologic agent for development of cervical cancer, clathrin-mediated endocytosis was described as infectious entry pathway. METHODOLOGY/PRINCIPAL FINDINGS: Using immunofluorescence and infection studies we show in contra…
Kokapstrādes uzņēmumu vizuālās identitātes vizuāli stilistiskie aspekti
2015
Diplomdarba temats ir „Kokapstrādes uzņēmumu vizuālās identitātes vizuāli stilistiskie aspekti”. Bakalaura darba mērķis ir izpētīt, kādas ir kokapstrādes uzņēmumu vizuālās identitātes un izstrādāt SIA „Ozoli AZ“ vizuālo identitāti. Šī bakalaura darba teorētiskajā daļā autore apkopo dažādu autoru atziņas par vizuālo identitāti un zīmola jēdzienu, identitātes uzbūvi un nozīmi. Bakalaura darba empīriskajā daļa ir apkopoti dati, kā arī analizēti pētījumā iegūtie rezultāti un veikti secinājumi. Diplomdarba radošajā daļā tiek izstrādāts projekts un aprakstīta tā tapšanas gaita un rezultāti. Darba autores izvirzītais pētījuma jautājums ir: kādas ir kokapstrādes uzņēmumu vizuālas identitātes kopīgā…
Learning across contexts: How can vocational teachers facilitate boundary learning for students in work-based placements?
2022
A well-known challenge in vocational education and training (VET) programmes is the lack of coherence between school-based and workplace learning. The Norwegian VET model consists of two years of upper secondary education followed by two years of apprenticeship at work. This small-scale study of vocational teacher’s vocational didactics aims to investigate boundary learning at the VET Programme for Sales and Service at the Norwegian upper secondary level. The research question explored is: How can vocational teachers improve boundary learning for students in work-based placements in the subject vocational in-depth study (YFF)? The methodological approach is qualitative interviews with vocat…