Search results for "ATF"
showing 10 items of 565 documents
Is Autophagy Altered in the Leukocytes of Type 2 Diabetic Patients?
2015
It is unknown whether autophagy is altered in the leukocytes of type 2 diabetes (T2D) patients and whether oxidative and endoplasmic reticulum (ER) stresses regulate this mechanism. We studied anthropometric and metabolic parameters and evaluated oxidative stress, chromatin condensation, ER stress, and autophagy parameters in leukocytes of 103 T2D patients versus 109 sex- and age-matched controls. Patients showed increases in glucose, insulin, homeostasis model assessment of insulin resistance, and glycated hemoglobin (HbA1c) compared with controls (p < 0.001). Leukocytes displayed enhanced total and mitochondrial reactive oxygen species (ROS), reduced mitochondrial mass, and increased chro…
Older adults who have previously fallen due to a trip walk differently than those who have fallen due to a slip
2014
Studying the relationships between centre of mass (COM) and centre of pressure (COP) during walking has been shown to be useful in determining movement stability. The aim of the current study was to compare COM-COP separation measures during walking between groups of older adults with no history of falling, and a history of falling due to tripping or slipping. Any differences between individuals who have fallen due to a slip and those who have fallen due to a trip in measures of dynamic balance could potentially indicate differences in the mechanisms responsible for falls. Forty older adults were allocated into groups based on their self-reported fall history during walking. The non-faller …
Acute neuromuscular responses to short and long roundhouse kick striking paces in professional Muay Thai fighters.
2019
International audience; BACKGROUND: Muay Thai fighters strongly rely on the use of the roundhouse kick due to its effectiveness (i.e. power) and implications on the final score. Therefore, different striking tempos at full power are used during training as a method to enhance kicking power. However, the neuromuscular responses are unknown. Thus, the goal of this study was to investigate neuromuscular responses to a single bout of shorter (every second = H1) and longer (every 3s = H3) kick striking time intervals, measured with the countermovement jump (CMJ).METHODS: Nine professional Muay Thai fighters participated in this randomized, cross-over trial. CMJs were measured on force plates bef…
Relationship between body composition and vertical ground reaction forces in obese children when walking.
2016
Abstract Background Obesity is now a serious worldwide challenge, especially in children. This condition can cause a number of different health problems, including musculoskeletal disorders, some of which are due to mechanical stress caused by excess body weight. The aim of this study was to determine the association between body composition and the vertical ground reaction force produced during walking in obese children. Methods Sixteen children participated in the study, six females and ten males [11.5 (1.2) years old, 69.8 (15.5) kg, 1.56 (0.09) m, and 28.36 (3.74) kg/m 2 of body mass index (BMI)]. Total weight, lean mass and fat mass were measured by dual-energy X-ray absorptiometry and…
Static postural control in children with developmental dyslexia
2006
Correspondence to: Service d’Ophtalmologie, CHU de Dijon, 3 rue du Faubourg Raines, F-21000 Dijon, France. Tel.: +33 3 80 24 68 74; fax: +33 3 80 24 11 39.; International audience; The present investigation tries to better understand potential association and causal relationship between phonological and postural impairment due to developmental dyslexia. The study included 50 boys with developmental dyslexia and selected on the basis of their overall reading difficulties, and 42 control boys. Body sway during a quite standing posture eye open and eye closed on a force platform were tested in the two groups of subjects that were between 10 and 13 years of age. Analysis of classical parameters…
Purchasing natural personal care products in the era of fake news? The moderation effect of brand trust
2021
Natural personal care products are gaining popularity due to their benefits in terms of health and well-being. However, consumers are wary of these products and are guided by the fake news circulating about them. Since natural product consumption offers several personal and environmental benefits, it would be worthwhile to understand consumers’ tendency to let fake news influence their consumption decisions. Accordingly, the current study examined the association of fake news and purchasing behaviour towards natural personal care products, utilising Stimulus-Organism-Behaviour-Consequence (SOBC) as the theoretical framework. The study proposed openness to change as the stimulus, perceived b…
Why do people purchase from food delivery apps? A consumer value perspective
2021
Consumers are increasingly using food delivery apps (FDAs) to facilitate convenient and quick food delivery. Yet, the existing research offers a limited understanding of consumers’ behavioral responses to the visibility and values derived from FDAs. Our study utilized the theory of consumption values (TCV) to examine associations between FDA visibility, consumption values, and purchase intentions. The mediating role of consumption values and the moderating role of attitude was also studied. A qualitative study was conducted with 15 FDA consumers to derive context-specific consumption values. Responses from 355 FDA consumers from the United States of America (USA) were obtained through Proli…
Versatile preparation of silica nanocapsules for biomedical applications
2020
Core–shell nanocapsules are receiving increasing interest for drug delivery applications. Silica nanocapsules have been the focus of intensive studies due to their biocompatibility, versatile silica chemistry, and tunable porosity. However, a versatile one-step preparation of silica nanocapsules with well-defined core–shell structure, tunable size, flexible interior loading, and tailored shell composition, permeability, and surface functionalization for site-specific drug release and therapeutic tracking remains a challenge. Herein, an interfacially confined sol–gel process in miniemulsion for the one-step versatile preparation of functional silica nanocapsules is developed. Uniform nanocap…
Development of a three-dimensional cell culture system based on microfluidics for nuclear magnetic resonance and optical monitoring
2014
A new microfluidic cell culture device compatible with real-time nuclear magnetic resonance (NMR) is presented here. The intended application is the long-term monitoring of 3D cell cultures by several techniques. The system has been designed to fit inside commercially available NMR equipment to obtain maximum readout resolution when working with small samples. Moreover, the microfluidic device integrates a fibre-optic-based sensor to monitor parameters such as oxygen, pH, or temperature during NMR monitoring, and it also allows the use of optical microscopy techniques such as confocal fluorescence microscopy. This manuscript reports the initial trials culturing neurospheres inside the micro…
Tulkošanas kvalitātes vērtēšanas platforma
2022
Mašīntulkošanas modeļa izstrādē ir svarīgi noteikt, vai jaunizstrādātais modelis ir labāks par iepriekšējo versiju. Visprecīzākais veids, kā to noteikt, ir ļaut cilvēkvērtētājiem vērtēt katra modeļa tulkošanas kvalitāti, bet cilvēkvērtēšana ir dārgs un laikietilpīgs process, tāpēc šī novērtēšana ir jāveic pēc iespējas efektīvi. Kvalifikācijas darba mērķis ir izstrādāt māšīntulkošanas kvalitātes vērtēšanas platformu, kas ļautu efektīvi un ātri cilvēkvērtētājiem novērtēt mašīntulka tulkotos teikumus un ar šīs informācijas palīdzību uzlabot mašīntulkošanas kvalitāti. Izstrādātā platforma ļauj pārvaldīt novērtēšanas kopas, veikt tiešo cilvēkvērtēšanu, analizēt, un eksportēt rezultātus. Izstrādā…