Search results for "ATF"

Impact of polymer-modified gold nanoparticles on brain endothelial cells: exclusion of endoplasmic reticulum stress as a potential risk factor

2016

A library of polymer-coated gold nanoparticles (AuNPs) differing in size and surface modifications was examined for uptake and induction of cellular stress responses in the endoplasmic reticulum (ER stress) in human brain endothelial cells (hCMEC/D3). ER stress is known to affect the physiology of endothelial cells (ECs) and may lead to inflammation or apoptosis. Thus, even if applied at non-cytotoxic concentrations ER stress caused by nanoparticles should be prevented to reduce the risk of vascular diseases and negative effects on the integrity of barriers (e.g. blood-brain barrier). We exposed hCMEC/D3 to twelve different AuNPs (three sizes: 18, 35, and 65 nm, each with four surface-modif…

Potencialidades de Google Maps en la investigación social aplicada

2019

In recent years, Google has devoted resources to build a complete map of the world. They constantly scan the territory, collecting a large amount of data that provides updated and complete geographic information. This allows us to have an interoperable map that provides the end user with a search tool, not only of routes but also of shops, equipment and any type of geo-referenced information. In addition, Google Maps provides a series of Application Programming Interface (API), which provides a library of set of subroutines, functions and procedures (in object-oriented programming) that can be used by other software to automate the extraction of information of the Google platform. These fre…

Effects of ibuprofen and carbamazepine on the ion transport system and fatty acid metabolism of temperature conditioned juveniles of Solea senegalens…

2018

The increasing presence of pharmaceuticals in aquatic environments in the last decades, derived from human and veterinary use, has become an important environmental problem. Previous studies have shown that ibuprofen (IB) and carbamazepine (CBZ) modify physiological and biochemical processes in Senegalese sole (Solea senegalensis) in a temperature-dependent manner. In other vertebrates, there is evidence that both of these pharmaceuticals interfere with the ‘arachidonic acid (AA) cascade’, which is responsible for the biosynthesis of numerous enzymes that are involved in the osmoregulatory process. The present work aims to study the temperature-dependent effects of these two pharmaceuticals…

Implant Abutment Cleaning by Plasma of Argon: 5-Year Follow-Up of a Randomized Controlled Trial.

2015

Contamination of implant abutments could potentially influence the peri-implant tissue inflammatory response. The aim of the present study is to assess the radiographic bone changes around customized, platform-switched abutments placed according to the "one-abutment-one-time" protocol, with and without plasma of argon cleaning treatment.Thirty healthy patients with thin gingival biotype (1 mm) and history of periodontal disease received one maxillary implant each. Immediately before abutment connection, patients were randomly assigned to control group (cleaning protocol by steaming) or test group (plasma of argon treatment). Outcome measures were: 1) success rate of implants and prostheses;…

Nutrient Assimilation by First-Feeding African Catfish, Clarias gariepinus , Assessed Using Stable Isotope Analysis

2013

Knowledge of ingredients assimilation and biomass contribution to recipient fish is important in feed formulation. The stable isotopes of 13C and 15N were used to investigate the assimilation and biomass contribution of bambaranut, Voandzeia subterranea, meal (BNM), corn, Zea mays, meal (CM) and fish meal (FM), in FM substituted diets of first feeding African catfish, Clarias gariepinus, during a 30-d experiment. The catfish larvae were stocked at 40 fish/15 L three replicate glass aquaria. Larvae were fed with experimental diets varying FM, BNM, and CM. Proportions of FM : BNM : CM in the experimental diets were: feed 1 (F1) 60:20:20; feed 2 (F2) 40:40:20; feed 3 (F3) 20:60:20; and feed 4 …

Towards the definitive evaluation framework for cross-platform app development approaches

2019

Abstract Mobile app development is hindered by device fragmentation and vendor-specific modifications. Boundaries between devices blur with PC-tablet hybrids on the one side and wearables on the other. Future apps need to support a host of app-enabled devices with differing capabilities, along with their software ecosystems. Prior work on cross-platform app development concerned concepts and prototypes, and compared approaches that target smartphones. To aid choosing an appropriate framework and to support the scientific assessment of approaches, an up-to-date comparison framework is needed. Extending work on a holistic, weighted set of assessment criteria, we propose what could become the …

Dizaina un struktūrskices izstrāde virtuālās realitātes platformai

2021

Projektā “VR SafeScaff” tiek risināta problēma par atbilstošu lietotāja pieredzes un lietotāja saskarnes izstrādi, kas nodrošina pēc iespējas ērtāku un uztveramāku lietojamību un dizainu, balstoties uz vairāku pētījumu rezultātiem. Darba mērķis ir izstrādāt struktūrskici un dizainu virtuālās realitātes projektam “VR SafeScaff”. Darba rezultātā tika izveidota dizaina struktūrskice virtuālās realitātes platformai “VR SafeScaff”, kura arī tika veiksmīgi implementēta pirmajā programmatūras versijā. Apmācības platformas pirmo versiju arī aplūkoja neatkarīgi lietotāji un būvniecības nozares lietotāji, kuri deva savus ieteikumus tā turpmākai projekta attīstībai un uzlabojumiem. Darba apjoms – 68. …

Design, synthesis and characterization of a theranostic nanoplatform for tumor site-specific delivery of doxorubicin

2022

Fatigue effects of marathon running on neuromuscular performance

2007

Nine experienced endurance runners performed individual marathon runs that involved several tests of neuromuscular performance before, during and after the marathon. The tests were performed with special force platform and dynamometer techniques. The results showed an overall decrease in performance from the marathon. The maximal sprint velocity decreased parabolically during the marathon, reaching the final value of 84% of the pre-marathon one. Similarly, the other test results after marathon indicated that maximal isometric knee extension torque was 78%, the performance in a special rebound test (drop jump) 84% and the 5-jump performance 92% of the pre-marathon values. These reductions we…

Paleoclimate and extensional tectonics of short-lived lacustrine environments. Lower Cretaceous of the Panormide Southern Tethyan carbonate platform …

2017

Abstract Subaerial erosion and continental sedimentation interbedded with shallow-water carbonates are unequivocal stratigraphic records to evaluate paleoenvironmental and paleoclimate evolution of emerged landmass. Stratigraphic analysis of the Cretaceous Monte Gallo section of the Mesozoic Panormide carbonate platform, in the northern side of the Palermo Mountains (NW Sicily) records a peculiar continental-derived clays that interrupted the shallow-water carbonate sedimentation. These clays rest, with lenticular geometries, above the tectonically-enhanced subaerial erosional unconformity of the Barremian-Lower Aptian Requienid limestones and are covered by the Upper Cretaceous Rudistid li…